scholarly journals Effect of formate and oxalate on fluid reabsorption from the proximal convoluted tubule of the anaesthetized rat.

1994 ◽  
Vol 477 (2) ◽  
pp. 347-354 ◽  
Author(s):  
M Wareing ◽  
R Green
Keyword(s):  
Proximal Convoluted Tubule ◽  
Fluid Reabsorption ◽  
Anaesthetized Rat

Recovery of proximal tubular function from ischemic injury

1984 ◽  
Vol 246 (2) ◽  
pp. F159-F166 ◽  
Author(s):  
P. A. Johnston ◽  
H. Rennke ◽  
N. G. Levinsky
Keyword(s):  
Angiotensin Ii ◽  
Brush Border ◽  
Proximal Convoluted Tubule ◽  
Sodium Reabsorption ◽  
Electron Microscopic ◽  
Early Recovery ◽  
Fluid Reabsorption ◽  
Microscopic Evaluation ◽  
Proximal Tubular ◽  
Total Glucose

Fluid (sodium) reabsorption, total glucose efflux, and reabsorption of angiotensin II and insulin from the proximal convoluted tubule were studied in rats by in vivo microperfusion. After 35 min of total renal artery occlusion, function was assessed at two intervals, 0-1 h (early recovery, ER) and 2-4 h (late recovery, LR). Light and electron microscopic evaluation showed 60-75% loss of proximal convoluted tubule brush border membrane in ER and nearly complete restoration of brush border in LR. No other structural abnormalities were evident. Renal blood flow was unchanged from control during both ER and LR. During ER, fluid reabsorption was reduced to 29.8 +/- 5.2%, and total glucose efflux, at normal tubule loads, to 73.9 +/- 5.5% of control. However, angiotensin II and insulin reabsorption were unchanged. In LR, fluid reabsorption remained significantly reduced at 54.3 +/- 8.1% of control. Total glucose efflux from the proximal tubule was normal in LR at glucose loads of up to 400 pmol X min-1, but was significantly reduced at higher loads. Passive glucose efflux, measured in the presence of 10(-4)M phloridzin, was not altered by ischemia. Brief ischemia results in significant alterations in proximal tubular reabsorption of sodium and glucose, which correlate with a substantial loss of brush border during ER. However, despite restoration of cell morphology to normal in LR, transport defects for both sodium and glucose persist.

Evidence for Angiotensin-Stimulated Proximal Tubular Fluid Reabsorption in Normotensive and Hypertensive Rats: Effect of Acute Administration of Captopril

1984 ◽  
Vol 66 (5) ◽  
pp. 541-544 ◽  
Author(s):  
P. J. Harris ◽  
L. G. Navar ◽  
D. W. Ploth
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Acute Administration ◽  
Fluid Absorption ◽  
Hypertensive Rats ◽  
Fluid Reabsorption ◽  
Arterial Blood ◽  
Proximal Tubular ◽  
Tubular Fluid Reabsorption ◽  
Anaesthetized Rat

1. The effects of captopril on mean arterial blood pressure and proximal tubular fluid re-absorption (Jv) were examined in anaesthetized normotensive rats and in the non-clipped kidneys of two-kidney, one-clip Goldblatt hypertensive rats. 2. In the normotensive animals, captopril reduced arterial blood pressure from 121 ± sd 9 to 106 ± 10 mmHg and Jv decreased from 3.78 ± 0.45 to 2.57 ± 0.58 × 10−4mm3mm−2s−1. Captopril had a greater effect on blood pressure in the hypertensive animals (172 ± 17 reduced to 133 ± 23 mmHg) although the decrease in Jv from 3.62 ± 0.12 to 2.40 ± 0.40 was similar to that observed in normotensive animals. 3. These results provide evidence that, in the anaesthetized rat, angiotensin II contributes to the maintenance of the rate of proximal fluid re-absorption. The magnitude of the angiotensin-stimulated component of proximal fluid absorption is similar in normotensive and two-kidney, one-clip Goldblatt hypertensive rats.

scholarly journals Hypocapnic but Not Metabolic Alkalosis Impairs Alveolar Fluid Reabsorption

2005 ◽  
Vol 171 (11) ◽  
pp. 1267-1271 ◽  
Author(s):  
Pavlos M. Myrianthefs ◽  
Arturo Briva ◽  
Emilia Lecuona ◽  
Vidas Dumasius ◽  
David H. Rutschman ◽  
...  
Keyword(s):  
Metabolic Alkalosis ◽  
Fluid Reabsorption

scholarly journals Nerve-Evoked Secretion of Immunoglobulin a in Relation to other Proteins by Parotid Glands in Anaesthetized Rat

2000 ◽  
Vol 85 (5) ◽  
pp. 511-518 ◽  
Author(s):  
G. B. Proctor ◽  
G. H. Carpenter ◽  
L. C. Anderson ◽  
J. R. Garrett
Keyword(s):  
Immunoglobulin A ◽  
Parotid Glands ◽  
Anaesthetized Rat
Sign in / Sign up

Export Citation Format

Share Document