scholarly journals Calcium entry through nicotinic receptor channels and calcium channels in cultured rat superior cervical ganglion cells.

1993 ◽  
Vol 468 (1) ◽  
pp. 53-71 ◽  
Author(s):  
J Trouslard ◽  
S J Marsh ◽  
D A Brown
Keyword(s):  
Calcium Channels ◽  
Superior Cervical Ganglion ◽  
Nicotinic Receptor ◽  
Ganglion Cells ◽  
Calcium Entry ◽  
Cervical Ganglion ◽  
Nicotinic Receptor Channels

scholarly journals Advancing age alters rapid and spontaneous refilling of caffeine-sensitive calcium stores in sympathetic superior cervical ganglion cells

2005 ◽  
Vol 99 (3) ◽  
pp. 963-971 ◽  
Author(s):  
Conwin K. Vanterpool ◽  
William J. Pearce ◽  
John N. Buchholz
Keyword(s):  
Calcium Channels ◽  
Superior Cervical Ganglion ◽  
Ganglion Cells ◽  
Smooth Endoplasmic Reticulum ◽  
Conditioning Stimulus ◽  
Calcium Stores ◽  
Fischer 344 ◽  
Sustain Release ◽  
Cervical Ganglion ◽  
Age Range

Intracellular calcium concentration ([Ca2+]i) release from smooth endoplasmic reticulum (SER) stores plays an important role in cell signaling. These stores are rapidly refilled via influx through voltage-gated calcium channels or spontaneously via store-operated calcium channels and subsequent pumping by SER Ca2+-ATPases. We measured [Ca2+]i transients in isolated fura 2-loaded superior cervical ganglion cells from 6-, 12-, 20-, and 24-mo-old Fischer 344 rats. For rapid refilling, [Ca2+]i transients were elicited by a 1) 5-s exposure to K+, 2) caffeine to release Ca2+ from SER stores, 3) K+ to refill SER Ca2+ stores, and 4) caffeine. The percent difference between the peak and rate of rise of the first and second caffeine-evoked [Ca2+]i transient significantly declined over the age range of 12–24 mo. To estimate spontaneous refilling, cells were depolarized for 5 s with 68 mM K+ (control), followed by a 10-s exposure to 10 mM caffeine “conditioning stimulus” to deplete [Ca2+]i stores. Caffeine was then rapidly applied for 5 s at defined intervals from 60 to 300 s. Integrated caffeine-evoked [Ca2+]i transients were measured and plotted as a percentage of the K+ response vs. time. The derivative of the refilling time curves significantly declined over the age range from 12–24 mo. Overall, these data suggest that the ability of superior cervical ganglion cells to sustain release of [Ca2+]i following rapid or spontaneous refilling declines with advancing age. Compromised ability to sustain calcium signaling may possibly alter the overall function of adrenergic neurons innervating the cerebrovasculature.

Effects of acetylcholine and adrenaline on axoplasmic transport at different regions of mouse superior cervical ganglion cells in culture

1995 ◽  
Vol 683 (1) ◽  
pp. 88-92 ◽  
Author(s):  
Tadashi Kawakami ◽  
Toshifumi Takenaka ◽  
Hideaki Hori ◽  
Yoko Hashimoto ◽  
Tatsumi Kusakabe
Keyword(s):  
Superior Cervical Ganglion ◽  
Ganglion Cells ◽  
Axoplasmic Transport ◽  
Cells In Culture ◽  
Cervical Ganglion

Effects of glucagon on axoplasmic transport in mouse superior cervical ganglion cells

Neuroreport ◽  
1999 ◽  
Vol 10 (11) ◽  
pp. 2401-2404
Author(s):  
Yang Tao ◽  
Hideaki Hori ◽  
Tadashi Kawakami ◽  
Yoko Hashimoto ◽  
Toshifumi Takenaka ◽  
...  
Keyword(s):  
Superior Cervical Ganglion ◽  
Ganglion Cells ◽  
Axoplasmic Transport ◽  
Cervical Ganglion
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