scholarly journals Intracellular calcium dynamics in response to action potentials in bullfrog sympathetic ganglion cells.

1992 ◽  
Vol 458 (1) ◽  
pp. 171-190 ◽  
Author(s):  
M Nohmi ◽  
S Y Hua ◽  
K Kuba
Keyword(s):  
Intracellular Calcium ◽  
Action Potentials ◽  
Sympathetic Ganglion ◽  
Ganglion Cells ◽  
Calcium Dynamics ◽  
Intracellular Calcium Dynamics

scholarly journals Action Potential–Induced Dendritic Calcium Dynamics Correlated With Synaptic Plasticity in Developing Hippocampal Pyramidal Cells

1999 ◽  
Vol 82 (4) ◽  
pp. 1993-1999 ◽  
Author(s):  
Yoshikazu Isomura ◽  
Nobuo Kato
Keyword(s):  
Synaptic Plasticity ◽  
Developmental Stage ◽  
Intracellular Calcium ◽  
Action Potentials ◽  
Pyramidal Cells ◽  
High Threshold ◽  
Calcium Dynamics ◽  
Ca1 Pyramidal Cells ◽  
Late Developmental Stage ◽  
Intracellular Calcium Dynamics

In hippocampal CA1 pyramidal cells, intracellular calcium increases are required for induction of long-term potentiation (LTP), an activity-dependent synaptic plasticity. LTP is known to develop in magnitude during the second and third postnatal weeks in the rats. Little is known, however, about development of intracellular calcium dynamics during the same postnatal weeks. We investigated postnatal development of intracellular calcium dynamics in the proximal apical dendrites of CA1 pyramidal cells by whole cell patch-clamp recordings and calcium imaging with the Ca2+ indicator fura-2. Dendritic calcium increases induced by intrasomatically evoked action potentials were slight during the first postnatal week but gradually became robust 3 to 6-fold during the second and third postnatal weeks. These calcium increases were blocked by application of 250 μM CdCl2, a nonspecific blocker for high-threshold voltage-dependent calcium channels (VDCCs). Under the voltage-clamp condition, both calcium currents and dendritic calcium accumulations induced by depolarization were larger at the late developmental stage (P15–18) than the early stage (P4–7), indicating developmental enhancement of calcium influx mediated by high-threshold VDCCs. Moreover, theta-burst stimulation (TBS), a protocol for LTP induction, induced large intracellular calcium increases at the late developmental stage, in synchrony with maturation of TBS-induced LTP. These results suggest that developmental enhancement of intracellular calcium increases induced by action potentials may underlie maturation of calcium-dependent functions such as synaptic plasticity in hippocampal neurons.

Intracellular calcium dynamics and cerebral injury: modeling various insults in vitro

1993 ◽  
Vol 613 (1) ◽  
pp. 156-159 ◽  
Author(s):  
Myung H. Kim-Lee ◽  
Bradford T. Stokes ◽  
Douglas K. Anderson
Keyword(s):  
Intracellular Calcium ◽  
Cerebral Injury ◽  
Calcium Dynamics ◽  
Intracellular Calcium Dynamics

scholarly journals Understanding anomalous delays in a model of intracellular calcium dynamics

2010 ◽  
Vol 20 (4) ◽  
pp. 045104 ◽  
Author(s):  
Emily Harvey ◽  
Vivien Kirk ◽  
Hinke M. Osinga ◽  
James Sneyd ◽  
Martin Wechselberger
Keyword(s):  
Intracellular Calcium ◽  
Calcium Dynamics ◽  
Intracellular Calcium Dynamics

scholarly journals Intracellular Calcium Dynamics and Anisotropic Reentry in Isolated Canine Pulmonary Veins and Left Atrium

Circulation ◽  
2005 ◽  
Vol 111 (22) ◽  
pp. 2889-2897 ◽  
Author(s):  
Chung-Chuan Chou ◽  
Motoki Nihei ◽  
Shengmei Zhou ◽  
Alex Tan ◽  
Ayaka Kawase ◽  
...  
Keyword(s):  
Intracellular Calcium ◽  
Left Atrium ◽  
Pulmonary Veins ◽  
Calcium Dynamics ◽  
Intracellular Calcium Dynamics
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