scholarly journals Intracoronary veratrine attenuates carotid baroreceptor reflex regulation of blood pressure in conscious dogs.

1992 ◽  
Vol 451 (1) ◽  
pp. 91-107
Author(s):  
A L Denison ◽  
R B Stephenson ◽  
S S Hull ◽  
K G Cornish ◽  
I H Zucker
Keyword(s):  
Blood Pressure ◽  
Baroreceptor Reflex ◽  
Conscious Dogs ◽  
Reflex Regulation ◽  
Carotid Baroreceptor ◽  
Regulation Of Blood Pressure

scholarly journals Role of potassium in the reflex regulation of blood pressure during static exercise in man.

1992 ◽  
Vol 451 (1) ◽  
pp. 643-651 ◽  
Author(s):  
N Fallentin ◽  
B R Jensen ◽  
S Byström ◽  
G Sjøgaard
Keyword(s):  
Blood Pressure ◽  
Static Exercise ◽  
Reflex Regulation ◽  
Regulation Of Blood Pressure

Blood Volume and the Carotid Baroreceptor Reflex in Conscious Rabbits

1981 ◽  
Vol 61 (s7) ◽  
pp. 173s-175s ◽  
Author(s):  
J. Ludbrook ◽  
I. B. Faris ◽  
G. G. Jamieson
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Cardiac Output ◽  
Systemic Vascular Resistance ◽  
Blood Volume ◽  
Vascular Resistance ◽  
Baroreceptor Reflex ◽  
Phase Lag ◽  
Carotid Baroreceptor ◽  
Conscious Rabbits

1. The effects of acute blood volume change in conscious rabbits on a.c. gain of the carotid baroreceptor reflex with respect to heart rate, blood pressure, cardiac output and systemic vascular resistance were studied. 2. With acute, isohaemic increase in blood volume by 20% and 40% the only consistent trend was a decrease in gain for systemic vascular resistance. 3. With acute reduction in blood volume there was a consistent tendency for gain for heart rate to fall. With 20% reduction in blood volume, gain for cardiac output fell but gain for systemic vascular resistance rose and its phase-lag became shorter, so that gain for blood pressure was unaltered. The enhanced gain for systemic vascular resistance was not sustained with 35% reduction in blood volume, so that gain for blood pressure fell. 4. Thus control of blood pressure by the carotid sinus reflex is remarkably unaffected by acute change in blood volume, and is impaired only when there is depression of gain for cardiac output without a concomitant rise in gain for systemic vascular resistance.

Carotid Baroreceptor Reflex in Normotensive and Hypertensive Subjects

1976 ◽  
Vol 51 (s3) ◽  
pp. 343s-345s ◽  
Author(s):  
G. Mancia ◽  
J. Ludbrook ◽  
A. Ferrari ◽  
L. Gregorini ◽  
R. Valentini ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Baroreceptor Reflex ◽  
The Other ◽  
Reflex Response ◽  
Arterial Blood ◽  
Carotid Baroreceptor ◽  
Normotensive Subjects ◽  
Neck Chamber ◽  
Related Increase

1. A graded decrease and increase in carotid baroreceptor activity (induced by a varying pressure in a neck chamber) caused a linearly related increase and decrease in arterial blood pressure. This occurred in both normotensive and hypertensive subjects. 2. Decrease of carotid baroreceptor activity caused a greater increase of blood pressure in normotensive than in hypertensive subjects. Increasing the activity caused changes of similar magnitude in the two groups. 3. Decrease of baroreceptor activity also caused an increase in heart rate although increasing the activity of the reflex had little effect on heart rate, particularly in normotensive subjects. Thus the carotid baroreceptor effect on blood pressure does not always reflect that on heart rate and inference of one reflex response from measurement of the other may be in error.

scholarly journals Carotid Body Baroreceptor Preservation and Control of Arterial Pressure in Eversion Carotid Endarterectomy

2019 ◽  
Vol 29 (01) ◽  
pp. 033-038
Author(s):  
Thomas Kotsis ◽  
Panagitsa Christoforou ◽  
Konstantinos Nastos
Keyword(s):  
Blood Pressure ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Carotid Endarterectomy ◽  
Internal Carotid ◽  
Baroreceptor Reflex ◽  
Carotid Baroreceptor ◽  
Proximal Internal Carotid Artery ◽  
Postoperative Hypertension ◽  
The Mean

AbstractThe technique of the eversion carotid endarterectomy (ECEA), as an alternative to the conventional endarterectomy with primary or patch angioplasty, is an established technique for managing internal carotid artery stenoses and recently its application has been upgraded through the European Society for Vascular Surgery guidelines (Recommendation 55: Class 1, Level A). However, the typical eversion method has been associated with postoperative hypertension due to loss of the baroreceptor reflex; the standard oblique transection at the bulb performed in the eversion endarterectomy interrupts either the baroreceptor sensoring tissue, which is mostly located in the adventitia at the medial portion of the proximal internal carotid artery, or even the proper Hering nerve, a branch of the glossopharyngeal nerve. These actions deregulate the natural negative feedback of the carotid baroreceptor. Guided by the anatomical location of the baroreceptor sensor we have elaborated a slight modification of the classical ECEA to maintain as much as possible of the viable carotid baroreceptor sensoring surface. By extending the oblique incision distal to the carotid bifurcation in the medial part of the internal carotid artery stem, an eyebrow-like part of the proximal internal carotid artery is maintained and the axis from the sensoring tissue to the nerve of Hering is protected and following the endarterectomy, postoperative arterial blood pressure levels are lower than in the classical ECEA due to the maintenance of the efficiency of the baroreceptor reflex. During the period from September 2016 to November 2018, carotid endarterectomy was performed in 57 patients. Twenty-eight of them underwent the typical ECEA and 29 patients had the modified eyebrow eversion carotid endarterectomy (me-ECEA). The changes of blood pressure baseline during the postoperative course in ECEA and me-ECEA group were analyzed and compared. Postoperative hypertension was defined as an elevation of systolic blood pressure (SBP) greater than 140 mm Hg. Patients who underwent typical ECEA had significantly higher postoperative blood pressure values compared with those who underwent me-ECEA. Actually, the mean postoperative SBP was 172.67 ± 24.59 mm Hg in the typical ECEA group compared with 160.86 ± 12.83 mm Hg in the me-ECEA group (p = 0.023). The mean diastolic blood pressure in the ECEA group was 65.42 ± 11.39 mm Hg compared with 58.06 ± 9.06 mm Hg in the me-ECEA group (p = 0.009). Our proposed me-ECEA technique seems to be related to lower rates of postoperative hypertension compared with the typical ECEA, probably due to the sparing of the main mass of the baroreceptor apparatus; this improved modification (me-ECEA) of the typical eversion procedure could represent an alternative ECEA technique with its inherent advantages.

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