scholarly journals The effect of stimulation of the atrial receptors on plasma cortisol level in the dog.

1989 ◽  
Vol 413 (1) ◽  
pp. 299-313 ◽  
Author(s):  
M J Drinkhill ◽  
D A Mary
Keyword(s):  
Cortisol Level ◽  
Plasma Cortisol ◽  
Plasma Cortisol Level ◽  
Atrial Receptors ◽  
Stimulation Of

Changes in circadian rhythm and suppression of the plasma cortisol level after prolonged stress in the sheep

1985 ◽  
Vol 110 (4) ◽  
pp. 540-545 ◽  
Author(s):  
F. Przekop ◽  
E. Stupnicka ◽  
E. Wolińska-Witort ◽  
K. Mateusiak ◽  
B. Sadowski ◽  
...  
Keyword(s):  
Circadian Rhythm ◽  
Cortisol Level ◽  
Plasma Cortisol ◽  
Plasma Cortisol Level ◽  
Diurnal Variations ◽  
Cortisol Response ◽  
Time Of Application ◽  
Prolonged Stress ◽  
Similar Decrease ◽  
Stimulation Of

Abstract. Diurnal variations in the plasma cortisol level were studied in anoestrous, pro-oestrous and pregnant ewes subjected to weak electric stimulation of the forelimbs 9 h daily for 3 consecutive days. In non-pregnant ewes the cortisol level rose on each of the 3 days when the stimulation was applied and then decreased on the day following the stimulation. A similar decrease in plasma cortisol concentrations in pregnant ewes appeared on the second day of footshocking. The acrophase of the circadian rhythm on electrostimulation days was synchronous with the time of application of footshocks; therefore, in stimulated ewes it was significantly accelerated compared to the prestimulatory day. A decrease in the plasma cortisol level in pro-oestrous and pregnant ewes was accompanied by disappearance of its normal rhythmicity. Since a normal plasma cortisol response to exogenous corticotrophin was noted after 3 days of foot-shocking it seems unlikely that the decrease in the cortisol level after prolonged stress was caused by exhaustion of the adrenal cortex. Some central mechanisms which could account for the biphasic changes in the plasma cortisol level and for disturbances of the hormone diurnal rhythmicity under conditions of prolonged stress are discussed.

STIMULATION OF CARP INTERRENAL FUNCTION BY ADRENOCORTICOTROPHIN

1976 ◽  
Vol 68 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Z. ILAN ◽  
Z. YARON
Keyword(s):  
Protein Binding ◽  
Cortisol Level ◽  
Plasma Cortisol ◽  
Plasma Cortisol Level ◽  
Cortisol Concentration ◽  
Transient Rise ◽  
Competitive Protein Binding ◽  
Cortisol Release ◽  
Stimulation Of

SUMMARY The effect of ACTH on cortisol concentration in the plasma of the carp has been studied; cortisol was determined using a competitive protein-binding radioassay. Blood was sampled at 12.00 h (the diurnal minimum) by cardiac puncture. The plasma cortisol level of undisturbed carp (blood obtained 1–3 min after netting) was 46 ± 14 (s.e.m.) ng/ml. One hour after injection of ACTH (1·0 i.u./100 g body wt., i.m.) the level of cortisol increased to 415 ± 62 ng/ml and reached a maximum of 656 ± 62 ng/ml after 2 h. The level of cortisol in saline-injected control carp after 2 h was 72 ± 33 ng/ml. A transient rise of cortisol was noted in both groups 30 min after injection (315 ± 51, 315 ± 62 ng/ml). This was attributed to a surge of endogenous ACTH, presumably due to handling. Carp head kidneys were superfused in vitro. They released cortisol spontaneously, but the releasing rate declined exponentially and reached a minimum after 135 min. Addition of ACTH to the medium was followed by a prompt increase in cortisol release. The rate of cortisol release was maximal 30–45 min after addition of ACTH and was identical to the rate at the beginning of the superfusion.

Plasma Cortisol Levels in Depression

1966 ◽  
Vol 112 (493) ◽  
pp. 1263-1267 ◽  
Author(s):  
R. J. Doig ◽  
R. V. Mummery ◽  
M. R. Wills ◽  
A. Elkes
Keyword(s):  
Diurnal Variation ◽  
Sleep Disturbance ◽  
Cortisol Level ◽  
Plasma Cortisol ◽  
Normal Subjects ◽  
Plasma Cortisol Level ◽  
Fundamental Characteristic ◽  
Sleep Period ◽  
Cortisol Levels ◽  
Abrupt Rise

Sleep disturbance is commonly found in depression. Plasma cortisol levels in non-hospitalized normal subjects show a rise prior to waking, with peak values at between 5 and 8 a.m. (9, 10). In a group of eight normal subjects, Perkoff (10) changed the sleep rhythm to sleeping during the day, using darkened rooms, and found that the plasma cortisol level followed suit, rising sharply in the two-hour period before waking. He stated: “A fundamental characteristic of the diurnal variation of plasma 17 OHCS concentration is the abrupt rise which occurs during the sleep period.”

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