scholarly journals The variability of muscle nerve sympathetic activity in resting recumbent man

1977 ◽  
Vol 272 (2) ◽  
pp. 383-397 ◽  
Author(s):  
Göran Sundlöf ◽  
B. Gunnar Wallin
Keyword(s):  
Sympathetic Activity ◽  
Muscle Nerve

scholarly journals Possible genetic influence on the strength of human muscle nerve sympathetic activity at rest.

Hypertension ◽  
1993 ◽  
Vol 22 (3) ◽  
pp. 282-284 ◽  
Author(s):  
B G Wallin ◽  
M M Kunimoto ◽  
J Sellgren
Keyword(s):  
Sympathetic Activity ◽  
Human Muscle ◽  
Genetic Influence ◽  
Muscle Nerve

The increase in sympathetic nerve activity after glucose ingestion is reduced in type I diabetes

2000 ◽  
Vol 98 (5) ◽  
pp. 627-632 ◽  
Author(s):  
Jan FAGIUS ◽  
Christian BERNE
Keyword(s):  
Sympathetic Activity ◽  
Type I Diabetes ◽  
Diabetic Patients ◽  
Type I ◽  
Sympathetic Outflow ◽  
Control Subjects ◽  
Glucose Ingestion ◽  
Muscle Nerve ◽  
Normal Strength ◽  
Diabetes Patients

Food intake is followed by an increase in baroreflex-governed sympathetic outflow to muscle vessels. It is established that insulin contributes to this stimulation; however, the increase occurs (to a lesser degree) even in the absence of enhanced insulin secretion. To further elucidate the role of insulin, muscle nerve sympathetic activity was recorded by microneurography, and the increase after an oral 100-g glucose load in eight C-peptide-negative patients with type I diabetes without any signs of neuropathy was compared with that in 16 healthy control subjects. The level of sympathetic activity at rest was similar in the two groups (type I diabetes patients, 19.5±2.4 bursts/min; controls, 20.4±4.8 bursts/min; means±S.D.). Following glucose intake there was a significant increase in activity in both groups, with maximum values at 30 min of 24.3±3.7 bursts/min for type I diabetes patients and 34.4±9.1 bursts/min for controls. The summarized response (during 90 min) of the diabetic patients was less than half that of the control subjects (P = 0.0003). It is concluded that the response of muscle nerve sympathetic activity to glucose ingestion is reduced to about half of its normal strength in the absence of insulin, and that there is no difference in sympathetic outflow at rest between healthy subjects and diabetic patients without polyneuropathy.

Muscle–Nerve Sympathetic Activity in Man. Relationship to Blood Pressure in Resting Normo- and Hyper-Tensive Subjects

1978 ◽  
Vol 55 (s4) ◽  
pp. 387s-389s ◽  
Author(s):  
G. Sundlöf ◽  
B. G. Wallin
Keyword(s):  
Blood Pressure ◽  
Negative Correlation ◽  
Sympathetic Activity ◽  
Diastolic Pressure ◽  
Pressure Fluctuations ◽  
Blood Pressure Level ◽  
Heart Beat ◽  
Arterial Blood ◽  
Muscle Nerve ◽  
Pressure Changes

1. Simultaneous recordings of multi-unit muscle nerve sympathetic activity and arterial blood pressure were made in 29 subjects, 17 healthy and 12 hypertensive. The neural activity, quantified by counting the number of pulse-synchronous sympathetic bursts in the mean voltage neurogram (burst incidence), was plotted against blood pressure. The effect of spontaneous temporary blood pressure fluctuations was studied by correlating different pressure parameters of individual heart beats to the occurrence of a sympathetic burst. 2. Between subjects there were marked differences in burst incidence but no correlation was found to interindividual differences in blood pressure level. 3. When for each heart beat the occurrence of a burst was correlated to different pressure parameters there was a close negative correlation to diastolic, a low correlation to systolic, and an intermediate negative correlation to mean blood pressure. 4. In a given subject, when comparing heart beats with the same diastolic pressure, the occurrence and the amplitudes of the sympathetic bursts were higher during falling than during rising pressure. This directional dependence of the muscle—nerve sympathetic activity was slightly more pronounced in the hypertensive group, but this was considered secondary to the hypertension. 5. The findings of an intimate correlation with dynamic variations in blood pressure and the absence of correlation to the static blood pressure suggest that the sympathetic outflow to skeletal muscle is of importance for buffering acute blood pressure changes but has little influence on the long-term blood pressure.

scholarly journals Muscle nerve sympathetic activity during sleep and its change with arousal response

1992 ◽  
Vol 1 (3) ◽  
pp. 178-185 ◽  
Author(s):  
TETSUO SHIMIZU ◽  
YUJI TAKAHASHI ◽  
KAZUMASA SUZUKI ◽  
SUSUMU KOGAWA ◽  
TETSUO TASHIRO ◽  
...  
Keyword(s):  
Sympathetic Activity ◽  
Muscle Nerve ◽  
Arousal Response
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