scholarly journals Studies on the mechanism of action of angiotensin on ion transport by kidney cortex slices

1972 ◽  
Vol 224 (1) ◽  
pp. 195-206 ◽  
Author(s):  
K. A. Munday ◽  
B. J. Parsons ◽  
Judith A. Poat
Keyword(s):  
Ion Transport ◽  
Mechanism Of Action ◽  
Kidney Cortex ◽  
Cortex Slices ◽  
Kidney Cortex Slices

Ion Transport and Oxygen Consumption in Kidney Cortex Slices from Young and Old Rats

Gerontology ◽  
1985 ◽  
Vol 31 (3) ◽  
pp. 166-173 ◽  
Author(s):  
Fulgencio Proverbio ◽  
Teresa Proverbio ◽  
Reinaldo Marín
Keyword(s):  
Oxygen Consumption ◽  
Ion Transport ◽  
Kidney Cortex ◽  
Old Rats ◽  
Cortex Slices ◽  
Kidney Cortex Slices

Effect of Pentobarbital Sodium on Uptake of PAH by Rat Kidney Cortex Slices in Vitro

1958 ◽  
Vol 195 (2) ◽  
pp. 343-346 ◽  
Author(s):  
E. J. Støren
Keyword(s):  
Oxygen Consumption ◽  
Renal Cortex ◽  
Rat Kidney ◽  
Kidney Cortex ◽  
Tissue Respiration ◽  
Rat Kidney Cortex ◽  
Pentobarbital Sodium ◽  
Cortex Slices ◽  
Kidney Cortex Slices

Active uptake of PAH by rat renal cortex slices was studied by the method of Cross and Taggart. Uptake was determined at low and at high medium concentrations of PAH. Pentobarbital sodium in concentrations comparable to those found in plasma during anesthesia, significantly depressed the uptake of PAH on all occasions. Simultaneously oxygen consumption was reduced. Acetate failed to stimulate PAH uptake in the presence of pentobarbital, although tissue respiration was restored to normal.

Effect of osmotic shocks on rabbit kidney cortex slices

1983 ◽  
Vol 244 (6) ◽  
pp. F696-F705
Author(s):  
R. Gilles ◽  
C. Duchene ◽  
I. Lambert
Keyword(s):  
Cell Volume ◽  
Volume Regulation ◽  
Rabbit Kidney ◽  
Kidney Cortex ◽  
Regulation Mechanism ◽  
Kidney Slices ◽  
Regulation Process ◽  
Maximum Cell ◽  
Cortex Slices ◽  
Kidney Cortex Slices

Rabbit kidney cortex slices behave an osmometers when withstanding hyperosmotic or hyposmotic shocks of amplitude up to pi 1/pi 2 = 1.25. For hyposmotic shocks of amplitude larger than or equal to pi 1/pi 2 = 1.50, the maximum swelling achieved is less than what can be expected on the basis of the van't Hoff relation, thereby indicating that a volume regulation process is taking place. Volume regulation in kidney slices can be dissociated into two distinct phases. The first one, of swelling limitation, is very rapid and keeps maximum cell volume at values lower than expected when the tissue is considered as an osmometer. This phase is followed by a slow volume readjustment process during which volume progressively decreases towards control values. The major intracellular osmotic effector loss during both swelling limitation and volume readjustment is Na+. The overall volume regulation process is insensitive to furosemide, vanadate, and bumetanide. Swelling limitation is blocked by addition of ouabain. Contrary to what has been believed previously, there is, however, no need to implicate control of the activity of a ouabain-sensitive, Na+/K+ pump in the Na-dependent volume regulation mechanism.

Sign in / Sign up

Export Citation Format

Share Document