scholarly journals The carbon dioxide balance-sheets of the body: their determination in normal subjects and in cases of congenital heart disease*

1955 ◽  
Vol 129 (1) ◽  
pp. 142-158 ◽  
Author(s):  
R. J. Shephard
Keyword(s):  
Carbon Dioxide ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Normal Subjects ◽  
The Body ◽  
Balance Sheets ◽  
Carbon Dioxide Balance

scholarly journals Being parent of a child with congenital heart disease, what does it mean? A qualitative research

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Nahid Dehghan Nayeri ◽  
Zahra Roddehghan ◽  
Farzad Mahmoodi ◽  
Parvin Mahmoodi
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Healthcare Professionals ◽  
Life Experience ◽  
The Body ◽  
Spiritual Needs ◽  
Structured Interviews ◽  
Financial Condition ◽  
Data Saturation

Abstract Background Childbirth is one of the invaluable human experiences and is associated with parental happiness. However, when a child is born with congenital heart disease, it creates emotional and mental distress. As a result, it changes the parents’ response to their child birth. Exploring parenthood experiences add to the body of knowledge and reveal new perspectives. In order to make healthcare professionals able to support these children and their families, they should first understand the meaning of this phenomenon. This study aimed to explore the meaning of parenting a child with Congenital Heart Disease in Iran. Methods A qualitative study was adopted with a conventional content analysis approach and constant comparative analysis. Participants in this study were 17 parents, including parents of children with congenital heart disease who were selected by purposeful sampling method. Semi-structured interviews were used for data collection and continued to data saturation. Data were analyzed via MAXQDA 10 software. Results Four categories and twenty three subcategories emerged as meaning of parenting a child with Congenital Heart Disease. Categories include “Emotional breakdown”, “The catastrophic burden of care”, “Spiritual beliefs of parents” and “The hard road” Conclusions Fully understanding the life experience of these families will allow the implementation of targeted health interventions. Hence, by understanding the meaning of parenting a child with Congenital Heart Disease, healthcare professionals can asses parents emotional statues, information and spiritual needs, financial condition, insurance and marital status using CHD standards so that support is individualized, sensitive and time appropriate.

Effect of Variation in Arterial Carbon Dioxide Levels on Cerebral-Somatic Oxygenation in Children with Cyanotic Congenital Heart Disease

2018 ◽  
pp. 1-6
Keyword(s):  
Carbon Dioxide ◽  
Congenital Heart Disease ◽  
Blood Flow ◽  
Heart Disease ◽  
Infrared Spectroscopy ◽  
Congenital Heart ◽  
Near Infrared ◽  
Cyanotic Congenital Heart Disease ◽  
Anesthesia Induction ◽  
Arterial Blood

Background: Hypocapnia is suggested in decreasing pulmonary vascular resistance in cyanotic congenital heart disease patients undergoing definitive repair. But its effects on cerebral and renal circulation are unclear. Hence the effect of changes in arterial blood carbon dioxide tensions (PaCo2 ) on cerebral (ScO2 %) and renal (SsO2 %) oxygenation indices using Near Infrared spectroscopy (NIRS) is examined. Methods: We did a prospective observational study in sixty-eight children who underwent elective cardiac surgery for various cyanotic congenital heart diseases. PaCo2 , ScO2 % and SsO2 % were obtained before induction of anesthesia, after anesthesia induction at normocapnic or mild hypercapnic ventilation (EtCo2 =40 mmHg) and again at hypocapnic ventilation (EtCo2 =30 mmHg). Regression analysis was done between PaCo2 and NIRS-C/ScO2 % and PaCo2 and NIRS-R/SsO2 % at both EtCo2 40 and 30 mmHg. Repeated measure analysis performed to evaluate the significance of change in NIRS-C and NIRS-R from pre-anesthesia induction to when EtCo2 was 40 and then 30 mmHg post anesthesia induction. Results: With decrease in EtCo2 , PaCo2 (p=0.0001), NIRS-C (p=0.0001) and NIRS-R (p=0.0001) decreased significantly. At EtCo2 of 40 and 30 mmHg, PaCo2 had significant positive correlation with NIRS-C (R2 =0.77, p=0.0001 and R2 =0.92, p=0.0001 respectively) and had insignificant correlation with NIRS-R (R2 =0.03, p=0.12 and R2 =0.008, p=0.46 respectively). Significant changes in NIRS-C {p=0.0001} and NIRS-R {p=0.0001} occurred from pre-induction to when EtCo2 was 40 and then to 30 mmHg. Conclusion: A decrease in NIRS-C and NIRS-R is probably from decreased cerebral and splanchnic blood flow during hypocapnic ventilation, leading to demand supply mismatch. Hypocapnic ventilation in cyanotic children has potential to cause cerebral hypoxia. Abbreviations: CCHD: Cyanotic Congenital Heart Disease; QP: Pulmonary blood flow; Do2 : Oxygen delivery; SpO2 : peripheral pulse oximetry; NIRS: Near Infrared Spectroscopy; NIRS-C/ScO2 %: Regional Cerebral Oxygen saturation; NIRS-R/SsO2 %: Regional Somatic/renal Oxygen saturation; HCT: Hematocrit; ECG: Electrocardiography; CPB: cardiopulmonary bypass; TOF: Tetralogy of fallot; BDG: Bidirectional Glenn Shunt; BT shunt: Blalock Taussig shunt; DORV: Double outlet right ventricle; FiO2 : Inspired oxygen concentration; ABG: Arterial blood gas; PaO2 : Arterial oxygen partial pressure; PaCo2 : Arterial carbon dioxide partial pressure; HR: Heart rate; MAP: Mean Arterial Pressure; CVP: Central Venous Pressure

First Case of Human Infection Caused by Pasteurella gallinarum Causing Infective Endocarditis in an Adolescent 10 Years After Surgical Correction for Truncus Arteriosus

PEDIATRICS ◽  
1995 ◽  
Vol 95 (6) ◽  
pp. 944-948
Author(s):  
Mohammad Al Fadel Saleh ◽  
Mohammad S. Al-Madan ◽  
Hashim H. Erwa ◽  
Ivy Defonseka ◽  
Saira Z. Sohel ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Infective Endocarditis ◽  
Congenital Heart ◽  
Human Infection ◽  
The Body ◽  
Surgical Correction ◽  
Truncus Arteriosus ◽  
Causative Organism ◽  
First Case

Objective. To report the first case of human infection (infective endocarditis [IEI]) caused by Pasteurella gallinarum and to review the literature regarding IE caused by the genus Pasteurella. Setting. University hospital based. Patient. An adolescent boy who underwent successful correction for truncus arteriosus 10 years before the present illness. Results. Persistent fever, pallor, and a palpable spleen suggested IE clinically. Echocardiography documented vegetation in the conduit that was used for surgical correction. Blood cultures grew P. gallinarum and confirmed its role as the causative organism for IE in the patient. Conclusion. This case illustrates that IE may develop in a child with congenital heart disease several years after surgical intervention using material that is foreign to the body (conduit), and that such a complication may involve unusual pathogens. These observations emphasize the need for careful long-term follow-up of children with congenital heart disease even after successful surgical correction.

The postoperative pathology of congenital heart disease

1993 ◽  
Vol 3 (2) ◽  
pp. 147-157 ◽  
Author(s):  
Robert H. Anderson ◽  
Siew Yen Ho
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Operative Procedure ◽  
Late Phase ◽  
Careful Analysis ◽  
The Body ◽  
Pulmonary Vasculature ◽  
Long Term Effects ◽  
Foreign Materials

AbstractThe role of the pathologist is changing with regard to the assessment of postoperative congenital heart disease. Whereas, in the past, the access to autopsied hearts provided the opportunity for detailed description and classification, nosologic details of cardiac malformations are now largely agreed. While a detailed analysis of the lesion remains an integral part of the pathologist's task, future advances will now largely be dictated by careful analysis of the effects of cardiac surgery. Such analysis can be divided into early and late phases. When assessing the specimen from a death occurring in the operating room or in the immediate postoperative period, the pathologist must examine carefully the operative incisions, and the correctness of the surgical procedure. Proper assessment of the procedure will necessitate removal of patches and pathways constructed by the surgeon, having documented carefully the location of sutures used to secure the foreign materials. The autopsy must also include assessment of the organs in the rest of the body, particularly the lungs, and must not ignore the immediate effect of the operative procedure on myocardial status. In the late phase, while again assessing in detail the access to the heart and the procedures employed during surgical correction, the pathologist will take care to evaluate the long-term effects of the procedure on the valves of the heart, the myocardium, the pulmonary vasculature and the other organs. At this stage, care should also be taken to ensure that late scarring does not involve the conduction tissues. Particular care will be needed when assessing the efficacy and durability of prosthetic materials inserted into the heart. Most of these steps will be undertaken intuitively by the pathologist, but interest in cardiac pathology as a specialty seems to be waning. The clinician can combat this trend by ensuring that all cases dying after operative procedures are obtained for autopsy, and by encouraging the pathologist to become involved in this fascinating area.

Application of Cardiovascular Angiography in Diagnosis of Heart Disease Based on Adaptive Tracking Circular Template Technique

2020 ◽  
Vol 10 (12) ◽  
pp. 2944-2951
Author(s):  
Duqiu Liu ◽  
Zheng Jia ◽  
Qian Liu ◽  
Xuting Wu ◽  
Zhenbo Wang ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Congenital Heart ◽  
Venous Malformation ◽  
Quantitative Description ◽  
Pulmonary Atresia ◽  
The Body ◽  
Adaptive Tracking ◽  
Circular Template

Objective: To explore the application value of cardiovascular extraction technique in the complex and/or complex malformation of congenital heart disease (CHD) and the application of deep learning to the diagnosis of medical imaging. Methods: Quantitative description of cardiovascular lesions and reconstruction of three-dimensional cardiovascular using angiographic images, the cardiovascular representation of the contrast image as a single pixel wide cardiovascular skeleton, using a rotating Gaussian function to enhance the image, using adaptive tracking circular template pair Enhanced cardiovascular images for cardiovascular extraction. The 360 cases of complex and/or complex malformation were analyzed and their association with clinical examinations such as echocardiography. Results: This group of 360 patients (including 75 cases of pulmonary atresia with ventricular septal defect, 62 cases of right ventricular double exit, 60 cases of tetralogy of Fallot, 52 cases of single ventricle, 42 cases of aortic dislocation, 15 cases of tricuspid atresia, 6 cases of coronary artery Abnormalities, 5 cases of complete pulmonary venous malformation, 5 cases of complete endocardial pad defect, 4 cases of common arterial trunk, 3 cases of interventricular complete pulmonary atresia, 7 cases of other cases and 24 cases of postoperative examination) angiography. Compared with ultrasound, the latter was corrected in 34 cases, missed diagnosis in 30 cases, and misdiagnosis in 16 cases of combined malformation. The detection and diagnosis of collateral vessels, coronary artery malformations and branches of pulmonary arteries and their abnormalities in complex and/or complex malformations are superior to echocardiography, and can measure pulmonary arterial and venous pressures and collateral vessel pressure It is superior to other imaging methods. Conclusions: Cardiac angiography (DSA) is still important for the diagnosis and differential diagnosis of difficult cases of congenital heart disease complex and/or complex malformation, especially showing the whole appearance and related lesions of the body, lung and coronary branches, as well as measuring pulmonary artery and ventricular pressure.

Sign in / Sign up

Export Citation Format

Share Document