scholarly journals Comparison of operation of spinal locomotor networks activated by supraspinal commands and by epidural stimulation of the spinal cord in cats

2020 ◽  
Vol 598 (16) ◽  
pp. 3459-3483 ◽  
Author(s):  
Pavel E. Musienko ◽  
Vladimir F. Lyalka ◽  
Oleg V. Gorskii ◽  
Natalia Merkulyeva ◽  
Yuri P. Gerasimenko ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Epidural Stimulation ◽  
Stimulation Of

Percutaneous epidural stimulation of the spinal cord for relief of pain

1978 ◽  
Vol 48 (3) ◽  
pp. 323-328 ◽  
Author(s):  
Bruno J. Urban ◽  
Blaine S. Nashold
Keyword(s):  
Spinal Cord ◽  
Dorsal Column ◽  
Long Term Results ◽  
Percutaneous Technique ◽  
Intractable Pain ◽  
Epidural Stimulation ◽  
Content Type ◽  
Major Operation ◽  
Stimulation Of

✓ Percutaneous epidural stimulation of the spinal cord was carried out in 20 patients with intractable pain. The procedure proved simple, and no major complications were encountered. The long-term results were comparable to the results obtained after a dorsal column stimulator implant by laminectomy. The percutaneous technique allowed extended trial stimulation without committing the patient to a major operation. Those patients in whom stimulation did not alleviate pain could be identified during a 2-week observation period, and the system could be removed easily. Seven patients were placed on chronic autostimulation and only one of those failed to experience continuing pain relief throughout the follow-up time of up to 2 years. It is concluded that percutaneous epidural stimulation constitutes a valid alternative to dorsal column stimulator implantation.

The Effect of Percutaneous Epidural Stimulation of the Spinal Cord for Brachial Plexopathy

1993 ◽  
Vol 26 (2) ◽  
pp. 333
Author(s):  
Sang Chul Lee ◽  
Ik Hyun Choe ◽  
Sang Min Lee ◽  
Hae Kyoung Kim ◽  
Yong Lak Kim ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Brachial Plexopathy ◽  
Epidural Stimulation ◽  
Stimulation Of

Formation of locomotor patterns in decerebrate cats in conditions of epidural stimulation of the spinal cord

2005 ◽  
Vol 35 (3) ◽  
pp. 291-298 ◽  
Author(s):  
Yu. P. Gerasimenko ◽  
I. A. Lavrov ◽  
I. N. Bogacheva ◽  
N. A. Shcherbakova ◽  
V. I. Kucher ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Epidural Stimulation ◽  
Locomotor Patterns ◽  
Decerebrate Cats ◽  
Stimulation Of

scholarly journals Sensory restoration by epidural stimulation of dorsal spinal cord in upper-limb amputees

2019 ◽  
Author(s):  
Santosh Chandrasekaran ◽  
Ameya C. Nanivadekar ◽  
Gina P. McKernan ◽  
Eric R. Helm ◽  
Michael L. Boninger ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Upper Limb ◽  
Limb Amputation ◽  
Neural Pathways ◽  
Dorsal Spinal Cord ◽  
Epidural Stimulation ◽  
Epidural Spinal Cord Stimulation ◽  
Dorsal Spinal ◽  
Median Change ◽  
Stimulation Of

Restoring somatosensory feedback to people with limb amputations is crucial for improving prosthesis acceptance and function. Epidural spinal cord stimulation is a commonly used clinical procedure that targets sensory neural pathways in the dorsal spinal cord to treat pain conditions. A similar approach could be developed as a clinically translatable means to restore somatosensation in amputees. We show that epidural stimulation of the dorsal spinal cord evoked sensory percepts, perceived as emanating from the amputated arm and hand, in four people with upper-limb amputation. After an initial caudal movement immediately following the implantation, the leads stabilized, exhibiting a median migration of <5 mm (each electrode contact is 3 mm long) over the remainder of the study in all the subjects. This was reflected in the consistent locations of evoked percepts in the hand across four subjects throughout the period of implantation, which lasted up to 29 days. The median change in the centroid location was 1.2 to 35.3 mm and the median change in percept area was 0 to 40%. While most of the evoked percepts were paresthetic in nature, a subset was described as naturalistic (e.g. touch or pressure) in three subjects. Modulating the stimulus amplitude affected the perceived intensity of the sensation in all subjects. A variety of sensory percepts were evoked in all subjects irrespective of the level of amputation or the time since amputation, suggesting the approach is amenable to a diverse population of amputees.

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