scholarly journals The effect of sleep restriction, with or without high‐intensity interval exercise, on myofibrillar protein synthesis in healthy young men

2020 ◽  
Vol 598 (8) ◽  
pp. 1523-1536 ◽  
Author(s):  
Nicholas J. Saner ◽  
Matthew J.‐C. Lee ◽  
Nathan W. Pitchford ◽  
Jujiao Kuang ◽  
Gregory D. Roach ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
High Intensity ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Sleep Restriction ◽  
Interval Exercise ◽  
High Intensity Interval ◽  
Myofibrillar Protein Synthesis

Effects of L-citrulline supplementation on nitric oxide and antioxidant markers after high-intensity interval exercise in young men: a randomized controlled trial

2021 ◽  
pp. 1-23
Author(s):  
Kosar Valaei ◽  
Javad Mehrabani ◽  
Alexei Wong
Keyword(s):  
Nitric Oxide ◽  
High Intensity ◽  
Controlled Trial ◽  
Young Men ◽  
No Production ◽  
Double Blind ◽  
Interval Exercise ◽  
Damage Indices ◽  
High Intensity Interval ◽  
Antioxidant Markers

Abstract L-citrulline (L-Cit) is a nonessential amino acid that stimulates nitric oxide (NO) production and improves exercise performance by reducing muscle damage indices; however, the direct benefits of L-Cit on antioxidant markers are unclear. The aim of this study was to examine antioxidant responses to high-intensity interval exercise following acute L-Cit supplementation. Nine young men (21 ± 1 years) participated in a double-blind crossover study in which they received 12 g of L-Cit and placebo (PL) an hour prior to high-intensity interval exercise on two occasions, separated by a seven-day washout period. Blood samples were obtained before (PRE), immediately after (IP), 10 (10P), and 30 min after exercise (30P) from the cubital vein using standard procedures. Serum concentrations of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), and NO metabolites (NOx) were measured. The exercise protocol significantly elevated SOD (p = 0.01) and GPx (p = 0.048) from PRE to 10P in the L-Cit group with greater changes than the PL group. CAT concentrations increased IP (p = 0.014) and remained elevated at 10P (p = 0.03) and 30P (p = 0.015) in both the L-Cit and PL conditions. NOx concentrations increased IP (p = 0.05) in the L-Cit group with greater changes than PL group in PRE to IP, PRE to 10P, and PRE to 30P (p < 0.05). Our data indicate that L-Cit supplementation (single 12 g dose pre-exercise) induces improvements in antioxidant markers following a session of high-intensity interval exercise in young men.

Impact of Short-term Sedentariness on Week-to-Week Myofibrillar Protein Synthesis Rates in Physically Active Young Men

2018 ◽  
Vol 50 (5S) ◽  
pp. 370
Author(s):  
Brandon J. Shad ◽  
Andrew M. Holwerda ◽  
Yasir S. Elhassan ◽  
Luc J.C. van Loon ◽  
Janice L. Thompson ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Short Term ◽  
Physically Active ◽  
Myofibrillar Protein Synthesis

scholarly journals Short-term muscle disuse induces a rapid and sustained decline in daily myofibrillar protein synthesis rates

2020 ◽  
Vol 318 (2) ◽  
pp. E117-E130 ◽  
Author(s):  
Sean P. Kilroe ◽  
Jonathan Fulford ◽  
Andrew M. Holwerda ◽  
Sarah R. Jackman ◽  
Benjamin P. Lee ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Deuterated Water ◽  
Short Term ◽  
Muscle Disuse ◽  
Before And After ◽  
Mri Scans ◽  
The Impact ◽  
Myofibrillar Protein Synthesis

Short-term muscle disuse has been reported to lower both postabsorptive and postprandial myofibrillar protein synthesis rates. This study assessed the impact of disuse on daily myofibrillar protein synthesis rates following short-term (2 and 7 days) muscle disuse under free living conditions. Thirteen healthy young men (age: 20 ± 1 yr; BMI: 23 ± 1 kg/m−2) underwent 7 days of unilateral leg immobilization via a knee brace, with the nonimmobilized leg acting as a control. Four days before immobilization participants ingested 400 mL of 70% deuterated water, with 50-mL doses consumed daily thereafter. Upper leg bilateral MRI scans and muscle biopsies were collected before and after 2 and 7 days of immobilization to determine quadriceps volume and daily myofibrillar protein synthesis rates. Immobilization reduced quadriceps volume in the immobilized leg by 1.7 ± 0.3 and 6.7 ± 0.6% after 2 and 7 days, respectively, with no changes in the control leg. Over the 1-wk immobilization period, myofibrillar protein synthesis rates were 36 ± 4% lower in the immobilized (0.81 ± 0.04%/day) compared with the control (1.26 ± 0.04%/day) leg ( P < 0.001). Myofibrillar protein synthesis rates in the control leg did not change over time ( P = 0.775), but in the immobilized leg they were numerically lower during the 0- to 2-day period (16 ± 6%, 1.11 ± 0.09%/day, P = 0.153) and were significantly lower during the 2- to 7-day period (44 ± 5%, 0.70 ± 0.06%/day, P < 0.001) when compared with the control leg. We conclude that 1 wk of muscle disuse induces a rapid and sustained decline in daily myofibrillar protein synthesis rates in healthy young men.

scholarly journals One Week of Step Reduction Lowers Myofibrillar Protein Synthesis Rates in Young Men

2019 ◽  
Vol 51 (10) ◽  
pp. 2125-2134 ◽  
Author(s):  
BRANDON J. SHAD ◽  
JANICE L. THOMPSON ◽  
ANDREW M. HOLWERDA ◽  
BEN STOCKS ◽  
YASIR S. ELHASSAN ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Myofibrillar Protein Synthesis

scholarly journals Day-to-Day Changes in Muscle Protein Synthesis in Recovery From Resistance, Aerobic, and High-Intensity Interval Exercise in Older Men

2015 ◽  
Vol 70 (8) ◽  
pp. 1024-1029 ◽  
Author(s):  
Kirsten E. Bell ◽  
Christopher Séguin ◽  
Gianni Parise ◽  
Steven K. Baker ◽  
Stuart M. Phillips
Keyword(s):  
Protein Synthesis ◽  
High Intensity ◽  
Muscle Protein ◽  
Muscle Protein Synthesis ◽  
Older Men ◽  
Interval Exercise ◽  
High Intensity Interval

scholarly journals Myofibrillar Protein Synthesis to Traditional and Cluster Sets in Trained Young Men and Women

2018 ◽  
Vol 50 (5S) ◽  
pp. 646
Author(s):  
Amadeo F. Salvador ◽  
Sarah K. Skinner ◽  
Joseph W. Beals ◽  
Justin Parel ◽  
Alexander Ulanov ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Men And Women ◽  
Cluster Sets ◽  
Myofibrillar Protein Synthesis
Sign in / Sign up

Export Citation Format

Share Document