scholarly journals Changes in systemic and subcutaneous adipose tissue inflammation and oxidative stress in response to exercise training in obese black African women

2020 ◽  
Vol 598 (3) ◽  
pp. 503-515 ◽  
Author(s):  
Pamela A. Nono Nankam ◽  
Amy E. Mendham ◽  
Melony F. De Smidt ◽  
Dheshnie Keswell ◽  
Tommy Olsson ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Adipose Tissue ◽  
Exercise Training ◽  
Subcutaneous Adipose Tissue ◽  
African Women ◽  
Adipose Tissue Inflammation ◽  
Black African ◽  
Subcutaneous Adipose ◽  
Response To Exercise ◽  
And Oxidative Stress

scholarly journals Visceral and Subcutaneous Adipose Tissue Volumes Are Cross-Sectionally Related to Markers of Inflammation and Oxidative Stress

Circulation ◽  
2007 ◽  
Vol 116 (11) ◽  
pp. 1234-1241 ◽  
Author(s):  
Karla M. Pou ◽  
Joseph M. Massaro ◽  
Udo Hoffmann ◽  
Ramachandran S. Vasan ◽  
Pal Maurovich-Horvat ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Markers Of Inflammation ◽  
Subcutaneous Adipose ◽  
And Oxidative Stress

scholarly journals miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity

Diabetes ◽  
2018 ◽  
Vol 67 (12) ◽  
pp. 2541-2553 ◽  
Author(s):  
Eun-Hee Koh ◽  
Natasha Chernis ◽  
Pradip K. Saha ◽  
Liuling Xiao ◽  
David A. Bader ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Insulin Sensitivity ◽  
Subcutaneous Adipose Tissue ◽  
Adipose Tissue Inflammation ◽  
Improve Insulin Sensitivity ◽  
Tissue Inflammation ◽  
Subcutaneous Adipose

Increased global arterial and subcutaneous adipose tissue inflammation in patients with moderate-to-severe psoriasis

2016 ◽  
Vol 176 (3) ◽  
pp. 732-740 ◽  
Author(s):  
K.F. Hjuler ◽  
L.C. Gormsen ◽  
M.H. Vendelbo ◽  
A. Egeberg ◽  
J. Nielsen ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Severe Psoriasis ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation ◽  
Subcutaneous Adipose

scholarly journals Exercise Training Attenuates the Dysregulated Expression of Adipokines and Oxidative Stress in White Adipose Tissue

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Takuya Sakurai ◽  
Junetsu Ogasawara ◽  
Ken Shirato ◽  
Tetsuya Izawa ◽  
Shuji Oh-ishi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Adipose Tissue ◽  
Exercise Training ◽  
White Adipose Tissue ◽  
Monocyte Chemoattractant Protein 1 ◽  
Enhanced Production ◽  
Lifestyle Related Diseases ◽  
Inflammatory Changes ◽  
The Impact ◽  
And Oxidative Stress

Obesity-induced inflammatory changes in white adipose tissue (WAT), which caused dysregulated expression of inflammation-related adipokines involving tumor necrosis factor-αand monocyte chemoattractant protein-1, contribute to the development of insulin resistance. Moreover, current literature reports state that WAT generates reactive oxygen species (ROS), and the enhanced production of ROS in obese WAT has been closely associated with the dysregulated expression of adipokines in WAT. Therefore, the reduction in excess WAT and oxidative stress that results from obesity is thought to be one of the important strategies in preventing and improving lifestyle-related diseases. Exercise training (TR) not only brings about a decrease in WAT mass but also attenuates obesity-induced dysregulated expression of the adipokines in WAT. Furthermore, some reports indicate that TR affects the generation of oxidative stress in WAT. This review outlines the impact of TR on the expression of inflammation-related adipokines and oxidative stress in WAT.

721-P: Exercise Training Alters Subcutaneous Adipose Tissue Morphology in Obese Adults Even without Weight Loss

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 721-P
Author(s):  
CHIWOON AHN ◽  
BENJAMIN J. RYAN ◽  
JENNA B. GILLEN ◽  
ALISON LUDZKI ◽  
MICHAEL W. SCHLEH ◽  
...  
Keyword(s):  
Weight Loss ◽  
Adipose Tissue ◽  
Exercise Training ◽  
Subcutaneous Adipose Tissue ◽  
Obese Adults ◽  
Tissue Morphology ◽  
Subcutaneous Adipose

scholarly journals Exercise training-induced effects on the abdominal subcutaneous adipose tissue phenotype in humans with obesity

2018 ◽  
Vol 125 (5) ◽  
pp. 1585-1593 ◽  
Author(s):  
Rudi Stinkens ◽  
Bram Brouwers ◽  
Johan W. Jocken ◽  
Ellen E. Blaak ◽  
Karianna F. Teunissen-Beekman ◽  
...  
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
Exercise Training ◽  
Protein Expression ◽  
Training Program ◽  
Mitochondrial Biogenesis ◽  
Subcutaneous Adipose Tissue ◽  
Exercise Training Program ◽  
Progressive Exercise ◽  
Subcutaneous Adipose

Rodent studies have indicated that physical exercise may improve adipose tissue function. We investigated the effects of a 12-wk supervised, progressive exercise training program on adipocyte morphology and abdominal subcutaneous adipose tissue function in metabolically well-phenotyped subjects with obesity. Men with obesity ( n = 21) participated in a 12-wk supervised, progressive, combined exercise training program consisting of aerobic exercise (30 min at 70% of maximal power output 2 times/wk) and resistance exercise (3 × 10 repetitions at 60% of 1 repeated maximum 1 time/wk), with adjustment of exercise intensity every 4 wk. At baseline and after intervention, abdominal subcutaneous adipose tissue biopsies were collected to determine 1) adipocyte morphology, 2) gene expression of markers for lipolysis, inflammation, browning, adipokines, and mitochondrial biogenesis/function, 3) protein expression of mitochondrial oxidative phosphorylation (OXPHOS) complexes, and 4) ex vivo basal and β2-adrenergic stimulated lipolysis. The exercise training program, which increased maximal aerobic capacity ( P < 0.001) and muscle strength ( P < 0.001), slightly reduced adipose tissue mass (~0.7 kg, P = 0.021) but did not affect abdominal subcutaneous adipocyte size ( P = 0.744), adipose tissue gene expression of markers for mitochondrial biogenesis and function, browning, lipolysis, inflammation and adipokines, total OXPHOS protein content ( P = 0.789), or β2-adrenergic sensitivity of lipolysis ( P = 0.555). A 12-wk supervised, progressive exercise training program did not alter abdominal subcutaneous adipocyte morphology and adipose tissue gene/protein expression of markers related to adipose tissue function or β2-adrenergic sensitivity of lipolysis in male subjects with obesity.NEW & NOTEWORTHY Studies that investigated the effects of exercise training on adipose tissue function in well-phenotyped humans are scarce. We demonstrate that 12 wk of supervised exercise training improved physical fitness and peripheral insulin sensitivity but did not alter abdominal subcutaneous adipocyte morphology, adipose tissue gene and protein expression of markers related to adipose tissue function, or β2-adrenergic receptor-mediated lipolysis in men with obesity. A prolonged and/or more intense training program may be required to improve human adipose tissue function.

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