scholarly journals Subcutaneous maternal resveratrol treatment increases uterine artery blood flow in the pregnant ewe and increases fetal but not cardiac growth

2019 ◽  
Vol 597 (20) ◽  
pp. 5063-5077 ◽  
Author(s):  
Jack R. T. Darby ◽  
Brahmdeep S. Saini ◽  
Jia Yin Soo ◽  
Mitchell C. Lock ◽  
Stacey L. Holman ◽  
...  
Keyword(s):  
Blood Flow ◽  
Uterine Artery ◽  
Artery Blood Flow ◽  
Cardiac Growth ◽  
Resveratrol Treatment ◽  
Pregnant Ewe

scholarly journals P07.04: Uterine artery blood flow volume is reduced in human pregnancies with increase utero-placental downstream impedance

2006 ◽  
Vol 28 (4) ◽  
pp. 569-569
Author(s):  
S. Boito ◽  
S. Rigano ◽  
G. Pennati ◽  
L. Mandia ◽  
A. Padoan ◽  
...  
Keyword(s):  
Blood Flow ◽  
Uterine Artery ◽  
Flow Volume ◽  
Artery Blood Flow ◽  
Blood Flow Volume

scholarly journals Activation of angiotensin type 2 receptor attenuates testosterone-induced hypertension and uterine vascular resistance in pregnant rats

2021 ◽  
Author(s):  
Jay S Mishra ◽  
Sathish Kumar
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Vascular Function ◽  
Uterine Artery ◽  
Artery Blood Flow ◽  
Protein Levels ◽  
Angiotensin Type 2 Receptor ◽  
Enos Protein ◽  
Angiotensin Type

Abstract Preeclampsia is a pregnancy-related hypertensive disorder with unclear mechanisms. While hypersensitivity to angiotensin II via vasoconstrictive angiotensin type-1 receptor (AT1R) is observed in preeclampsia, the importance of vasodilatory angiotensin type-2 receptor (AT2R) in the control of vascular dysfunction is less clear. We assessed whether AT1R, AT2R and eNOS expression is altered in placental vessels of preeclamptic women and tested if ex vivo incubation with AT2R agonist Compound 21 (C21; 1 μM) could restore AT1R, AT2R and eNOS balance. Further, using a rat model of gestational hypertension induced by elevated testosterone, we examined whether C21 (1 μg·kg−1·day−1, oral) could preserve AT1R and AT2R balance and improve blood pressure, uterine artery blood flow, and vascular function. Western blots revealed that AT1R protein level was higher while AT2R and eNOS protein were reduced in preeclamptic placental vessels, and AT2R agonist C21 decreased AT1R and increased AT2R and eNOS protein levels in preeclamptic vessels. In testosterone-dams, blood pressure was higher, and uterine artery blood flow was reduced, and C21 treatment reversed these levels similar to those in controls dams. C21 attenuated the exaggerated Ang II contraction and improved endothelium-dependent vasorelaxation in uterine arteries of testosterone-dams. These C21-mediated vascular effects were associated with decreased AT1R and increased AT2R and eNOS protein levels. C21 also increased serum nitrate/nitrite and bradykinin production in testosterone-dams and attenuated the feto-placental growth restriction. Thus, AT1R upregulation and AT2R downregulation is observed in preeclampsia and testosterone-model, and increasing AT2R activity could help restore AT1R and AT2R balance and improve gestational vascular function.

Comparison of uterine artery blood flow with levonorgestrel intrauterine system and copper intrauterine device

Contraception ◽  
2011 ◽  
Vol 83 (6) ◽  
pp. 578-581 ◽  
Author(s):  
Berna Haliloglu ◽  
Aygen Celik ◽  
Erdin Ilter ◽  
Serpil Bozkurt ◽  
Umit Ozekici
Keyword(s):  
Blood Flow ◽  
Uterine Artery ◽  
Intrauterine Device ◽  
Artery Blood Flow ◽  
Copper Intrauterine Device

Effect of the copper-intrauterine device (TCu 380A) on subendometrial microvascularization and uterine artery blood flow

2006 ◽  
Vol 86 (6) ◽  
pp. 1780-1782 ◽  
Author(s):  
Mirela F. Jiménez ◽  
Eduardo P. Passos ◽  
Paulo A.P. Fagundes ◽  
Fernando M. de Freitas ◽  
Elisangela Arbo ◽  
...  
Keyword(s):  
Blood Flow ◽  
Uterine Artery ◽  
Intrauterine Device ◽  
Artery Blood Flow ◽  
Copper Intrauterine Device

Use of ultrasonic Doppler waveforms to estimate changes in uterine artery blood flow and vessel compliance.

1990 ◽  
Vol 68 (8) ◽  
pp. 2450 ◽  
Author(s):  
L R Waite ◽  
S P Ford ◽  
D F Young ◽  
A J Conley
Keyword(s):  
Blood Flow ◽  
Uterine Artery ◽  
Artery Blood Flow
Sign in / Sign up

Export Citation Format

Share Document