scholarly journals Maternal programming by hypoxia alters the molecular composition of the oviduct of her offspring, the first pathway her grandchildren will transit: a potential novel pathway for intergenerational programming?

2019 ◽  
Vol 597 (9) ◽  
pp. 2325-2326
Author(s):  
Peter W. Nathanielsz
Keyword(s):  
Molecular Composition ◽  
Maternal Programming ◽  
Intergenerational Programming

Alterations in Molecular Composition of Humic Substances from Eucalypt Plantation Soils Assessed by 13 C-NMR Spectroscopy

2012 ◽  
Vol 77 (1) ◽  
pp. 293-306 ◽  
Author(s):  
Emanuelle Mercês Barros Soares ◽  
Ivo Ribeiro Silva ◽  
Roberto Ferreira de Novais ◽  
Yan-Yan Hu ◽  
Klaus Schmidt-Rohr
Keyword(s):  
Nmr Spectroscopy ◽  
Humic Substances ◽  
Molecular Composition ◽  
Eucalypt Plantation ◽  
C Nmr

scholarly journals Effects of Platelet-Rich Plasma on Cellular Populations of the Central Nervous System: The Influence of Donor Age

2021 ◽  
Vol 22 (4) ◽  
pp. 1725
Author(s):  
Diego Delgado ◽  
Ane Miren Bilbao ◽  
Maider Beitia ◽  
Ane Garate ◽  
Pello Sánchez ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cellular Response ◽  
Platelet Rich Plasma ◽  
Biological Response ◽  
In Vitro Models ◽  
Molecular Composition ◽  
Cellular Models ◽  
The Central Nervous System

Platelet-rich plasma (PRP) is a biologic therapy that promotes healing responses across multiple medical fields, including the central nervous system (CNS). The efficacy of this therapy depends on several factors such as the donor’s health status and age. This work aims to prove the effect of PRP on cellular models of the CNS, considering the differences between PRP from young and elderly donors. Two different PRP pools were prepared from donors 65–85 and 20–25 years old. The cellular and molecular composition of both PRPs were analyzed. Subsequently, the cellular response was evaluated in CNS in vitro models, studying proliferation, neurogenesis, synaptogenesis, and inflammation. While no differences in the cellular composition of PRPs were found, the molecular composition of the Young PRP showed lower levels of inflammatory molecules such as CCL-11, as well as the presence of other factors not found in Aged PRP (GDF-11). Although both PRPs had effects in terms of reducing neural progenitor cell apoptosis, stabilizing neuronal synapses, and decreasing inflammation in the microglia, the effect of the Young PRP was more pronounced. In conclusion, the molecular composition of the PRP, conditioned by the age of the donors, affects the magnitude of the biological response.

scholarly journals Molecular composition distribution of polycarbonate/polystyrene blends in cylindrical nanopores

2011 ◽  
Vol 43 (7) ◽  
pp. 600-605 ◽  
Author(s):  
Hui Wu ◽  
Zhaohui Su ◽  
Atsushi Takahara
Keyword(s):  
Molecular Composition ◽  
Composition Distribution
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