scholarly journals Don't stop at the top: plasma volume expansion and pulmonary vasodilatation restore left ventricular function at rest but not during exercise at high altitude

2018 ◽  
Vol 597 (4) ◽  
pp. 995-996
Author(s):  
Elizabeth Karvasarski ◽  
Lucas Azevedo ◽  
David Granton ◽  
Stephen P. Wright
Keyword(s):  
Left Ventricular Function ◽  
High Altitude ◽  
Ventricular Function ◽  
Plasma Volume ◽  
Volume Expansion ◽  
Left Ventricular ◽  
Plasma Volume Expansion ◽  
Pulmonary Vasodilatation

The effect of 18 h of simulated high altitude on left ventricular function

2006 ◽  
Vol 98 (4) ◽  
pp. 411-418 ◽  
Author(s):  
Jesper Kjaergaard ◽  
Eric M. Snyder ◽  
Christian Hassager ◽  
Thomas P. Olson ◽  
Jae K. Oh ◽  
...  
Keyword(s):  
Left Ventricular Function ◽  
High Altitude ◽  
Ventricular Function ◽  
Left Ventricular ◽  
Simulated High Altitude

Effect of Re-Induction to High Altitude on Left Ventricular Function in Normal man

1978 ◽  
Vol 55 (3) ◽  
pp. 21P-21P
Author(s):  
V. Balasubramanian ◽  
O. P. Mathew ◽  
S. C. Tiwari ◽  
A. Behl ◽  
R. S. Hoon
Keyword(s):  
Left Ventricular Function ◽  
High Altitude ◽  
Ventricular Function ◽  
Left Ventricular ◽  
Normal Man

scholarly journals Left Ventricular Function during Acute High-Altitude Exposure in a Large Group of Healthy Young Chinese Men

PLoS ONE ◽  
2015 ◽  
Vol 10 (1) ◽  
pp. e0116936 ◽  
Author(s):  
Mingyue Rao ◽  
Jiabei Li ◽  
Jun Qin ◽  
Jihang Zhang ◽  
Xubin Gao ◽  
...  
Keyword(s):  
Left Ventricular Function ◽  
High Altitude ◽  
Ventricular Function ◽  
Left Ventricular ◽  
Chinese Men ◽  
Large Group ◽  
Altitude Exposure

Operation Everest III: role of plasma volume expansion onV˙o2 max during prolonged high-altitude exposure

2000 ◽  
Vol 89 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Paul Robach ◽  
Michèle Déchaux ◽  
Sébastien Jarrot ◽  
Jenny Vaysse ◽  
Jean-Christophe Schneider ◽  
...  
Keyword(s):  
High Altitude ◽  
Plasma Volume ◽  
Volume Expansion ◽  
Plasma Renin ◽  
Plasma Volume Expansion ◽  
Exercise Induced ◽  
Male Subjects ◽  
Increased Activity ◽  
Volume Decrease

We hypothesize that plasma volume decrease (ΔPV) induced by high-altitude (HA) exposure and intense exercise is involved in the limitation of maximal O2 uptake (V˙o2 max) at HA. Eight male subjects were decompressed for 31 days in a hypobaric chamber to the barometric equivalent of Mt. Everest (8,848 m). Maximal exercise was performed with and without plasma volume expansion (PVX, 219–292 ml) during exercise, at sea level (SL), at HA (370 mmHg, equivalent to 6,000 m after 10–12 days) and after return to SL (RSL, 1–3 days). Plasma volume (PV) was determined at rest at SL, HA, and RSL by Evans blue dilution. PV was decreased by 26% ( P < 0.01) at HA and was 10% higher at RSL than at SL. Exercise-induced ΔPV was reduced both by PVX and HA ( P < 0.05). Compared with SL, V˙o2 max was decreased by 58 and 11% at HA and RSL, respectively.V˙o2 max was enhanced by PVX at HA (+9%, P < 0.05) but not at SL or RSL. The more PV was decreased at HA, the moreV˙o2 max was improved by PVX ( P < 0.05). At exhaustion, plasma renin and aldosterone were not modified at HA compared with SL but were higher at RSL, whereas plasma atrial natriuretic factor was lower at HA. The present results suggest that PV contributes to the limitation ofV˙o2 max during acclimatization to HA. RSL-induced PVX, which may be due to increased activity of the renin-aldosterone system, could also influence the recovery ofV˙o2 max.

scholarly journals Alterations in left ventricular function in normal man on exposure to high altitude (3658 m).

Heart ◽  
1978 ◽  
Vol 40 (3) ◽  
pp. 276-285 ◽  
Author(s):  
V Balasubramanian ◽  
O P Mathew ◽  
S C Tiwari ◽  
A Behl ◽  
S C Sharma ◽  
...  
Keyword(s):  
Left Ventricular Function ◽  
High Altitude ◽  
Ventricular Function ◽  
Left Ventricular ◽  
Normal Man
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