scholarly journals The impact of 2 years of high‐intensity exercise training on a model of integrated cardiovascular regulation

2018 ◽  
Vol 597 (2) ◽  
pp. 419-429 ◽  
Author(s):  
Michinari Hieda ◽  
Erin J. Howden ◽  
Satyam Sarma ◽  
William Cornwell ◽  
Justin S. Lawley ◽  
...  
Keyword(s):  
Exercise Training ◽  
High Intensity ◽  
Cardiovascular Regulation ◽  
High Intensity Exercise ◽  
The Impact

THE IMPACT OF 2-YEARS HIGH INTENSITY EXERCISE TRAINING ON INTEGRATED CARDIOVASCULAR REGULATION

2018 ◽  
Vol 71 (11) ◽  
pp. A1796
Author(s):  
Michinari Hieda ◽  
Erin Howden ◽  
Satyam Sarma ◽  
William Cornwell ◽  
Marcus A. Urey ◽  
...  
Keyword(s):  
Exercise Training ◽  
High Intensity ◽  
Cardiovascular Regulation ◽  
High Intensity Exercise ◽  
The Impact

scholarly journals Intermittent and continuous high-intensity exercise training induce similar acute but different chronic muscle adaptations

2014 ◽  
Vol 99 (5) ◽  
pp. 782-791 ◽  
Author(s):  
Andrew J. R. Cochran ◽  
Michael E. Percival ◽  
Steven Tricarico ◽  
Jonathan P. Little ◽  
Naomi Cermak ◽  
...  
Keyword(s):  
Exercise Training ◽  
High Intensity ◽  
High Intensity Exercise ◽  
Muscle Adaptations

scholarly journals Functional high-intensity exercise training ameliorates insulin resistance and cardiometabolic risk factors in type 2 diabetes

2018 ◽  
Vol 103 (7) ◽  
pp. 985-994 ◽  
Author(s):  
Ciarán E. Fealy ◽  
Stephan Nieuwoudt ◽  
Julie A. Foucher ◽  
Amanda R. Scelsi ◽  
Steven K. Malin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Exercise Training ◽  
High Intensity ◽  
Cardiometabolic Risk ◽  
High Intensity Exercise ◽  
Cardiometabolic Risk Factors

Influence of high-intensity exercise training and anabolic androgenic steroid treatment on rat tissue glycogen content

Life Sciences ◽  
2005 ◽  
Vol 77 (9) ◽  
pp. 1030-1043 ◽  
Author(s):  
Tatiana Sousa Cunha ◽  
Ana Paula Tanno ◽  
Maria José Costa Sampaio Moura ◽  
Fernanda Klein Marcondes
Keyword(s):  
Exercise Training ◽  
High Intensity ◽  
Glycogen Content ◽  
Steroid Treatment ◽  
High Intensity Exercise ◽  
Anabolic Androgenic Steroid ◽  
Androgenic Steroid ◽  
Rat Tissue

Effects of high-amount–high-intensity exercise on in vivo platelet activation: Modulation by lipid peroxidation and AGE/RAGE axis

2013 ◽  
Vol 110 (12) ◽  
pp. 1232-1240 ◽  
Author(s):  
Francesca Santilli ◽  
Natale Vazzana ◽  
Pierpaolo Iodice ◽  
Stefano Lattanzio ◽  
Rossella Liani ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Exercise Training ◽  
Platelet Activation ◽  
High Intensity ◽  
Plasma Levels ◽  
High Intensity Exercise ◽  
Similar Amount ◽  
Activation Markers

SummaryPhysical activity is associated with cardiovascular risk reduction, but the effects of exercise on platelet activation remain controversial. We investigated the effects of regular high-amount, high intensity aerobic exercise on in vivo thromboxane (TX)-dependent platelet activation and plasma levels of platelet-derived proteins, CD40L and P-selectin, and whether platelet variables changes may be related to changes in high-density lipoprotein (HDL) and in the extent of oxidative stress and oxidative stress-related inflammation, as reflected by urinary isoprostane excretion and endogenous soluble receptor for advanced glycation end-products (esRAGE), respectively. Urinary excretion of 11-dehydro-TXB2 and 8-iso-prostaglandin (PG)F2α and plasma levels of P-selectin, CD40L and esRAGE were measured before and after a eight-week standardised aerobic high-amount–high-intensity training program in 22 sedentary subjects with low-to-intermediate risk. Exercise training had a clear beneficial effect on HDL cholesterol (+10%, p=0.027) and triglyceride (-27%, p=0.008) concentration. In addition, a significant (p<0.0001) decrease in urinary 11-dehydro-TXB2 (26%), 8-iso-PGF2α (21 %), plasma P-selectin (27%), CD40L (35%) and a 61% increase in esRAGE were observed. Multiple regression analysis revealed that urinary 8-iso-PGF2α [beta=0.33, SEM=0.116, p=0.027] and esRAGE (beta=-0.30, SEM=31.3, p=0.046) were the only significant predictors of urinary 11-dehydro-TXB2 excretion rate over the training period. In conclusion, regular high-amount–high-intensity exercise training has broad beneficial effects on platelet activation markers, paralleled and possibly associated with changes in the lipoprotein profile and in markers of lipid peroxidation and AGE/RAGE axis. Our findings may help explaining why a similar amount of exercise exerts significant benefits in preventing cardiovascular events.

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