scholarly journals Sodium nitroprusside dilates cerebral vessels and enhances internal carotid artery flow in young men

2018 ◽  
Vol 596 (17) ◽  
pp. 3967-3976 ◽  
Author(s):  
Niels D. Olesen ◽  
Mads Fischer ◽  
Niels H. Secher
1988 ◽  
Vol 16 (5-6) ◽  
pp. 405-409 ◽  
Author(s):  
Shimon Degani ◽  
Joav Paltiely ◽  
Reuven Lewinsky ◽  
Israel Shapiro ◽  
Mordechai Sharf

2004 ◽  
Vol 40 (1) ◽  
pp. 92-97 ◽  
Author(s):  
Enrique Criado ◽  
Manuel Doblas ◽  
Juan Fontcuberta ◽  
Antonio Orgaz ◽  
Angel Flores ◽  
...  

2009 ◽  
Vol 37 (12) ◽  
pp. 2428-2435 ◽  
Author(s):  
Afshin A. Divani ◽  
Tamara L. Berezina ◽  
Gabriela Vazquez ◽  
Sergey B. Zaets ◽  
Ramachandra Tummala ◽  
...  

2014 ◽  
Vol 35 (2) ◽  
pp. 312-318 ◽  
Author(s):  
Sepideh Amin-Hanjani ◽  
Xinjian Du ◽  
Dilip K Pandey ◽  
Keith R Thulborn ◽  
Fady T Charbel

Measurement of volume flow rates in major cerebral vessels can be used to evaluate the hemodynamic effects of cerebrovascular disease. However, both age and vascular anatomy can affect flow rates independent of disease. We prospectively evaluated 325 healthy adult volunteers using phase contrast quantitative magnetic resonance angiography to characterize these effects on cerebral vessel flow rates and establish clinically useful normative reference values. Flows were measured in the major intracranial and extracranial vessels. The cohort ranged from 18 to 84 years old, with 157 (48%) females. All individual vessel flows and total cerebral blood flow (TCBF) declined with age, at 2.6 mL/minute per year for TCBF. Basilar artery (BA) flow was significantly decreased in individuals with one or both fetal posterior cerebral arteries (PCAs). Internal carotid artery flows were significantly higher with a fetal PCA and decreased with a hypoplastic anterior cerebral artery. Indexing vessel flows to TCBF neutralized the age effect, but anatomic variations continued to impact indexed flow in the BA and internal carotid artery. Variability in normative flow ranges were reduced in distal vessels and by examining regional flows. Cerebral vessel flows are affected by age and cerebrovascular anatomy, which has important implications for interpretation of flows in the disease state.


Neurosurgery ◽  
2001 ◽  
Vol 48 (2) ◽  
pp. 328-333 ◽  
Author(s):  
Shoichiro Kawaguchi ◽  
Shuzo Okuno ◽  
Toshisuke Sakaki ◽  
Norikiyo Nishikawa

Abstract OBJECTIVE We evaluated the effect of carotid endarterectomy on chronic ocular ischemic syndrome due to internal carotid artery stenosis by use of data obtained from ophthalmic artery color Doppler flow imaging. METHODS We examined 11 patients with ocular ischemic syndrome due to internal carotid artery stenosis (>70% stenosis) who were being treated by carotid endarterectomy. Ophthalmic artery color Doppler flow imaging indicated ophthalmic artery flow direction and peak systolic flow velocity and was performed before and at 1 week, 1 month, and 3 months after surgery. RESULTS We assessed the ophthalmic arteries of 11 patients via color Doppler flow imaging. Before undergoing carotid endarterectomy, five patients showed reversed ophthalmic artery flow. In the other six patients who experienced antegrade ophthalmic artery flow, the average peak systolic flow velocity was 0.09 ± 0.05 m/s (mean ± standard deviation). Preoperative reversed flow resolved in each patient 1 week after undergoing surgery. All patients showed antegrade ophthalmic artery flow. The average peak systolic flow velocity in the patients who had preoperative antegrade flow rose significantly, to 0.21 ± 0.14 m/s (P < 0.05). There was no significant change as compared with findings at 1 week after surgery. During the follow-up period (mean, 32.4 mo), no patients complained of recurrent visual symptoms. At the end of the study period, visual acuity had improved in five patients and had not worsened in the other six patients. CONCLUSION Carotid endarterectomy was effective for improving or preventing the progress of chronic ocular ischemia caused by internal carotid artery stenosis.


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