scholarly journals The human element: moving beyond animal models to study the neuronal regulation of intestinal electrolyte transport

2016 ◽  
Vol 594 (2) ◽  
pp. 259-260
Author(s):  
Wallace MacNaughton
Keyword(s):  
Animal Models ◽  
Electrolyte Transport ◽  
Human Element ◽  
Neuronal Regulation ◽  
Intestinal Electrolyte Transport

scholarly journals Effect of Senokot on rat intestinal electrolyte transport

1984 ◽  
Vol 87 (3) ◽  
pp. 503-512 ◽  
Author(s):  
M. Donowitz ◽  
J. Wicks ◽  
L. Battisti ◽  
G. Pike ◽  
R. DeLellis
Keyword(s):  
Electrolyte Transport ◽  
Intestinal Electrolyte Transport

Intestinal Electrolyte Transport and Diarrheal Disease

1989 ◽  
Vol 321 (13) ◽  
pp. 879-883 ◽  
Author(s):  
Franklin H. Epstein ◽  
Michael Field ◽  
Mrinalini C. Rao ◽  
Eugene B. Chang
Keyword(s):  
Diarrheal Disease ◽  
Electrolyte Transport ◽  
Intestinal Electrolyte Transport

Intestinal ion transport and diarrheal disease

1986 ◽  
Vol 250 (1) ◽  
pp. G1-G8 ◽  
Author(s):  
J. D. Fondacaro
Keyword(s):  
Diarrheal Disease ◽  
Second Messengers ◽  
Water Flux ◽  
Electrolyte Transport ◽  
Secretory Diarrhea ◽  
Clinical Investigator ◽  
Body Of Knowledge ◽  
Intestinal Electrolyte Transport ◽  
Intracellular Mediators ◽  
Intestinal Ion Transport

The physiology of intestinal electrolyte transport is currently an area of intense research interest. Also, reports regularly appear that define possible roles of various endocrine, paracrine, and neurohumoral substances in regulating intestinal ion and water flux. A vast body of knowledge has appeared recently that focuses on the action of specific intracellular mediators or second messengers and certain biochemical events that are thought to be involved in this transport process. This area of research has drawn the attention of the clinical investigator as well as the basic scientist because of the implications of these findings to the understanding of secretory disorders of the gastrointestinal tract, in particular diarrheal disease. The purpose of this review is to focus on recent findings reported in three major areas: the physiology of intestinal electrolyte transport and its regulation; the pathophysiology of secretory diarrhea; and current thoughts and practices in the therapeutic approach to the disease.

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