scholarly journals Resistance exercise training and circulatory responses to feeding and skeletal muscle protein anabolism in older men

2015 ◽  
Vol 593 (17) ◽  
pp. 3771-3772
Author(s):  
Sara Y. Oikawa ◽  
Kirsten E. Bell ◽  
Amy J. Hector
Keyword(s):  
Skeletal Muscle ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Muscle Protein ◽  
Older Men ◽  
Skeletal Muscle Protein ◽  
Resistance Exercise Training

scholarly journals The effects of resistance exercise training on macro- and micro-circulatory responses to feeding and skeletal muscle protein anabolism in older men

2015 ◽  
Vol 593 (12) ◽  
pp. 2721-2734 ◽  
Author(s):  
Bethan E. Phillips ◽  
Philip J. Atherton ◽  
Krishna Varadhan ◽  
Marie C. Limb ◽  
Daniel J. Wilkinson ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Muscle Protein ◽  
Older Men ◽  
Skeletal Muscle Protein ◽  
Resistance Exercise Training

Heavy resistance exercise training and skeletal muscle androgen receptor expression in younger and older men

Steroids ◽  
2011 ◽  
Vol 76 (1-2) ◽  
pp. 183-192 ◽  
Author(s):  
Juha P. Ahtiainen ◽  
Juha J. Hulmi ◽  
William J. Kraemer ◽  
Maarit Lehti ◽  
Kai Nyman ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Androgen Receptor ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Older Men ◽  
Receptor Expression ◽  
Androgen Receptor Expression ◽  
Resistance Exercise Training ◽  
Heavy Resistance Exercise

Effect of growth hormone and resistance exercise on muscle growth and strength in older men

1995 ◽  
Vol 268 (2) ◽  
pp. E268-E276 ◽  
Author(s):  
K. E. Yarasheski ◽  
J. J. Zachwieja ◽  
J. A. Campbell ◽  
D. M. Bier
Keyword(s):  
Growth Hormone ◽  
Protein Synthesis ◽  
Muscle Strength ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Muscle Protein ◽  
Older Men ◽  
Whole Body ◽  
Synthesis Rate ◽  
Resistance Exercise Training

The purpose of this study was to determine whether growth hormone (GH) administration enhances the muscle protein anabolism associated with heavy-resistance exercise training in older men. Twenty-three healthy, sedentary men (67 +/- 1 yr) with low serum insulin-like growth factor I levels followed a 16-wk progressive resistance exercise program (75-90% max strength, 4 days/wk) after random assignment to either a GH (12.5-24 micrograms.kg-1.day-1; n = 8) or placebo (n = 15) group. Fat-free mass (FFM) and total body water increased more in the GH group. Whole body protein synthesis and breakdown rates increased in the GH group after treatment. However, increments in vastus lateralis muscle protein synthesis rate, urinary creatinine excretion, and training-specific isotonic and isokinetic muscle strength were similar in both groups, while 24-h urinary 3-methylhistidine excretion was unchanged after treatment. These observations suggest that resistance exercise training improved muscle strength and anabolism in older men, but these improvements were not enhanced when exercise was combined with daily GH administration. The greater increase in FFM with GH treatment may have been due to an increase in noncontractile protein and fluid retention.

scholarly journals Resistance exercise maintains skeletal muscle protein synthesis during bed rest

1997 ◽  
Vol 82 (3) ◽  
pp. 807-810 ◽  
Author(s):  
Arny A. Ferrando ◽  
Kevin D. Tipton ◽  
Marcas M. Bamman ◽  
Robert R. Wolfe
Keyword(s):  
Skeletal Muscle ◽  
Protein Synthesis ◽  
Resistance Training ◽  
Resistance Exercise ◽  
Lean Body Mass ◽  
Muscle Protein ◽  
Muscle Protein Synthesis ◽  
Bed Rest ◽  
Skeletal Muscle Protein ◽  
Skeletal Muscle Protein Synthesis

Ferrando, Arny A., Kevin D. Tipton, Marcas M. Bamman, and Robert R. Wolfe. Resistance exercise maintains skeletal muscle protein synthesis during bed rest. J. Appl. Physiol. 82(3): 807–810, 1997.—Spaceflight results in a loss of lean body mass and muscular strength. A ground-based model for microgravity, bed rest, results in a loss of lean body mass due to a decrease in muscle protein synthesis (MPS). Resistance training is suggested as a proposed countermeasure for spaceflight-induced atrophy because it is known to increase both MPS and skeletal muscle strength. We therefore hypothesized that scheduled resistance training throughout bed rest would ameliorate the decrease in MPS. Two groups of healthy volunteers were studied during 14 days of simulated microgravity. One group adhered to strict bed rest (BR; n = 5), whereas a second group engaged in leg resistance exercise every other day throughout bed rest (BREx; n = 6). MPS was determined directly by the incorporation of infusedl-[ ring-13C6]phenylalanine into vastus lateralis protein. After 14 days of bed rest, MPS in the BREx group did not change and was significantly greater than in the BR group. Thus moderate-resistance exercise can counteract the decrease in MPS during bed rest.

scholarly journals Aerobic and resistance exercise training reverses age‐dependent decline in NAD + salvage capacity in human skeletal muscle

2019 ◽  
Vol 7 (12) ◽  
Author(s):  
Roldan M. de Guia ◽  
Marianne Agerholm ◽  
Thomas S. Nielsen ◽  
Leslie A. Consitt ◽  
Ditte Søgaard ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Human Skeletal Muscle ◽  
Resistance Exercise Training ◽  
Age Dependent

Protein Metabolism and Age: Influence of Insulin and Resistance Exercise

2001 ◽  
Vol 11 (s1) ◽  
pp. S150-S163 ◽  
Author(s):  
Peter A. Farrell
Keyword(s):  
Skeletal Muscle ◽  
Protein Synthesis ◽  
Resistance Exercise ◽  
Muscle Protein ◽  
Muscle Protein Synthesis ◽  
Mrna Translation ◽  
Bed Rest ◽  
Skeletal Muscle Protein ◽  
Amino Acid Availability ◽  
Effects Of Aging

Skeletal muscle proteins are constantly being synthesized and degraded, and the net balance between synthesis and degradation determines the resultant muscle mass. Biochemical pathways that control protein synthesis are complex, and the following must be considered: gene transcription, mRNA splicing, and transport to the cytoplasm; specific amino acyl-tRNA, messenger (mRNA), ribosomal (rRNA) availability; amino acid availability within the cell; the hormonal milieu; rates of mRNA translation; packaging in vesicles for some types of proteins; and post-translational processing such as glycation and phosphorylation/dephosphorylation. Each of these processes is responsive to the need for greater or lesser production of new proteins, and many states such as sepsis, uncontrolled diabetes, prolonged bed-rest, aging, chronic alcohol treatment, and starvation cause marked reductions in rates of skeletal muscle protein synthesis. In contrast, acute and chronic resistance exercise cause elevations in rates of muscle protein synthesis above rates found in nondiseased rested organisms, which are normally fed. Resistance exercise may be unique in this capacity. This chapter focuses on studies that have used exercise to elucidate mechanisms that explain elevations in rates of protein synthesis. Very few studies have investigated the effects of aging on these mechanisms; however, the literature that is available is reviewed.

Sign in / Sign up

Export Citation Format

Share Document