NO synthesis stimulated by arachidonic acid accumulation via PPARα in acetylcholine‐stimulated gastric mucous cells

2021 ◽  
Author(s):  
Saori Tanaka ◽  
Shigenori Ito ◽  
Chikao Shimamoto ◽  
Hitoshi Matsumura ◽  
Toshio Inui ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Mucous Cells ◽  
Acid Accumulation ◽  
Gastric Mucous

Enhancement of Ca2+-regulated exocytosis by indomethacin in guinea-pig antral mucous cells: arachidonic acid accumulation

2005 ◽  
Vol 91 (1) ◽  
pp. 249-259 ◽  
Author(s):  
Shoko Fujiwara ◽  
Chikao Shimamoto ◽  
Yoshihiko Nakanishi ◽  
Ken-ichi Katsu ◽  
Masumi Kato ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Guinea Pig ◽  
Mucous Cells ◽  
Regulated Exocytosis ◽  
Acid Accumulation

Helicobacter pylori infection produces expression of secretory component in gastric mucous cells

2001 ◽  
Vol 120 (5) ◽  
pp. A708-A709
Author(s):  
T KANEKO ◽  
H OTA ◽  
M HAYAMA ◽  
K NAKAJIMA ◽  
A YOSHIZAWA ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Secretory Component ◽  
Helicobacter Pylori Infection ◽  
Mucous Cells ◽  
Gastric Mucous

Characterization of mucous cell synthetic functions in a new primary canine gastric mucous cell culture system

1990 ◽  
Vol 258 (5) ◽  
pp. G774-G787 ◽  
Author(s):  
C. R. Boland ◽  
E. R. Kraus ◽  
J. M. Scheiman ◽  
C. Black ◽  
G. D. Deshmukh ◽  
...  
Keyword(s):  
Culture System ◽  
Mucous Cell ◽  
Gastric Mucin ◽  
Enzyme Linked Immunosorbent Assay ◽  
Metabolic Labeling ◽  
Mucous Cells ◽  
Gastric Mucus ◽  
Adequate Model ◽  
Gastric Mucous Cell ◽  
Gastric Mucous

Mucin is a critical component of the protective layer secreted by gastrointestinal mucous cells. A detailed understanding of the molecular processing of gastric mucin and the physiology of its secretion has been limited by the lack of an adequate model for their study. We have developed a primary culture system of canine gastric mucous cells that has permitted us to study their synthetic and secretory functions. It was found that [3H]glucosamine used for metabolic labeling studies was incorporated into both mucin and lipid components of gastric mucus. To measure mucin with this model, a new immunoassay was developed to quantitate canine gastric mucin. Mucin was purified from the canine stomach, a polyclonal antibody was generated, and an enzyme-linked immunosorbent assay for gastric mucin was established. Mast cells were frequent contaminants of the gastric mucous cell preparation, and two methods were developed to limit their contamination. A new culture system has been developed for the study of gastric mucous cells. These cells synthesize and secrete both mucin and phospholipids. This system will permit us to study the molecular processing of mucin and the physiology of its production and release.

Oxytocin and vasopressin stimulate inositol phosphate production in human gestational myometrium and decidua cells

1986 ◽  
Vol 6 (7) ◽  
pp. 613-619 ◽  
Author(s):  
Michael P. Schrey ◽  
Alison M. Read ◽  
Philip J. Steer
Keyword(s):  
Arachidonic Acid ◽  
Inositol Phosphates ◽  
Inositol Phosphate ◽  
Diacylglycerol Lipase ◽  
Inositol 1 ◽  
Inositol Phosphate Production ◽  
Acid Accumulation ◽  
Free Arachidonic Acid ◽  
Hydrolysis Of ◽  
Related Increase

The involvement of phosphoinositide hydrolysis in the action of oxytocin and vasopressin on the uterus was investigated in gestational myometrium and decidua cells by measuring the production of inositol phosphates. Both peptides stimulated a dose related increase in all three inositol phosphates in myometrium. This may be related to the control of sarcoplasmic Ca++ levels in the myometrium. Oxytocin and vasopressin also stimulated inositol 1-phosphate (IP) production in decidua cells. The hydrolysis of phosphatidylinositol by decidua homogenates exhibited a precursor-product relationship for diacylglycerol and arachidonic acid accumulation. Hence both peptides may mobilise free arachidonic acid, for prostaglandin biosynthesis, from decidua cell phosphoinositides by the sequential action of phospholipase C and diacylglycerol lipase.

Renewal of mouse gastric mucous cells following fast neutron irradiation

1977 ◽  
Vol 183 (3) ◽  
pp. 303-318 ◽  
Author(s):  
W. Wattel ◽  
J. J. Geuze ◽  
D. G. de Rooij ◽  
J. A. G. Davids
Keyword(s):  
Fast Neutron ◽  
Neutron Irradiation ◽  
Mucous Cells ◽  
Fast Neutron Irradiation ◽  
Gastric Mucous

Synthesis and prostaglandin E2-induced secretion of surfactant phospholipid by isolated gastric mucous cells

1991 ◽  
Vol 100 (5) ◽  
pp. 1232-1240 ◽  
Author(s):  
James M. Scheiman ◽  
Eugene R. Kraus ◽  
Leslie A. Bonnville ◽  
Paul A. Weinhold ◽  
C.Richard Boland
Keyword(s):  
Prostaglandin E2 ◽  
Mucous Cells ◽  
Gastric Mucous

TNFA regulates c-fos and c-jun expression in isolated canine gastric mucous cells

2000 ◽  
Vol 118 (4) ◽  
pp. A741
Author(s):  
Edward Grand ◽  
Takayoshi Suzuki ◽  
Jung Park ◽  
Meizhi Wang ◽  
John Del Valle
Keyword(s):  
Mucous Cells ◽  
Gastric Mucous

Helicobacter pylori infection produces expression of a secretory component in gastric mucous cells

2000 ◽  
Vol 437 (5) ◽  
pp. 514-520 ◽  
Author(s):  
Taimei Kaneko ◽  
Hiroyoshi Ota ◽  
Masayoshi Hayama ◽  
Taiji Akamatsu ◽  
Tsutomu Katsuyama
Keyword(s):  
Helicobacter Pylori ◽  
Secretory Component ◽  
Helicobacter Pylori Infection ◽  
Mucous Cells ◽  
Gastric Mucous
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