scholarly journals Carotid stiffness, intima media thickness, and aortic augmentation index among adults with SARS‐CoV‐2

2021 ◽  
Author(s):  
Rachel E. Szeghy ◽  
Valesha M. Province ◽  
Nina L. Stute ◽  
Marc A. Augenreich ◽  
Laurel K. Koontz ◽  
...  
Keyword(s):  
Augmentation Index ◽  
Intima Media Thickness ◽  
Media Thickness ◽  
Carotid Stiffness

Arterial stiffness and carotid distensibility following acute formaldehyde exposure in female adults

2021 ◽  
pp. 074823372110316
Author(s):  
Nina L Stute ◽  
Jonathon L Stickford ◽  
Marc A Augenreich ◽  
Kyle C Kimball ◽  
Janet M Cope ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Vascular Function ◽  
Intima Media Thickness ◽  
Human Cadaver ◽  
Media Thickness ◽  
Carotid Stiffness ◽  
Short Term Exposure ◽  
Increased Risk ◽  
Carotid Distensibility ◽  
The Impact

Formaldehyde (FA) is a ubiquitous organic preservative used in several industries and represents an occupational health hazard. Short-term exposure to FA can increase oxidative stress and cause a decrease in conduit vessel function. These decrements in vascular function may extend to the arterial architecture, predisposing individuals to increased risk of cardiovascular disease. The purpose of this study was to investigate the impact of an acute 90-minute FA exposure period (259 ± 95 ppb) on indices of arterial architecture. Arterial stiffness and carotid distensibility as determined by central pressures, augmentation index (AIx), and carotid-femoral pulse wave velocity (cfPWV) ( n=13F, 24 ± 1 year) as well as carotid stiffness and intima media thickness (IMT) ( n = 9F, 23 ± 1 year) were assessed prior to (Pre-FA) and immediately following (Post-FA) exposure to FA in human cadaver dissection laboratories. Central pressures and cfPWV (Pre-FA: 5.2 ± 0.8 m.s−1, Post-FA: 5.2 ± 1.1 m s−1) were unchanged by acute FA exposure ( p > 0.05). Carotid stiffness parameters and distension were unchanged by acute FA exposure ( p > 0.05), although distensibility (Pre-FA: 33.9 ± 10.5[10–3*kPa−1], Post-FA: 25.9 ± 5.5[10–3*kPa-1], p < 0.05), and IMT (Pre-FA: 0.42 ± 0.05 mm, Post-FA: 0.51 ± 0.11 mm, p < 0.05) decreased and increased, respectively. Individual Pre- to Post-FA changes in these markers of arterial architecture did not correlate with levels of FA exposure ([FA]: 20–473 ppb) ( p > 0.05). Our group previously found vascular function decrements following acute FA exposure in human cadaver laboratories; here we found that carotid distensibility and intima media thickness are altered following FA exposure.

P2.18 IMPACT OF CARDIOVASCULAR RISK FACTORS ON CAROTID STIFFNESS AND CAROTID INTIMA MEDIA THICKNESS – GENDER DIFFERENCES

2015 ◽  
Vol 12 (C) ◽  
pp. 10
Author(s):  
Maria Loboz-Rudnicka* ◽  
Joanna Jaroch ◽  
Zbigniew Bociaga ◽  
Barbara Rzyczkowska ◽  
Ewa Kruszynska ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gender Differences ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness ◽  
Carotid Stiffness

scholarly journals Relationship of arterial wall parameters to cardiovascular risk factors and cardiovascular risk assessed by SCORE system

Medicina ◽  
2007 ◽  
Vol 43 (7) ◽  
pp. 529 ◽  
Author(s):  
Milda Kovaitė ◽  
Žaneta Petrulionienė ◽  
Ligita Ryliškytė ◽  
Jolita Badarienė ◽  
Alma Čypienė ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Arterial Wall ◽  
Pulse Wave ◽  
Augmentation Index ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness ◽  
Flow Mediated Dilatation

Objective. To investigate the relationship of arterial wall parameters (flow-mediated dilatation of the brachial artery, augmentation index, pulse wave velocity, stiffness index, carotid intima-media thickness) to conventional cardiovascular risk factors and cardiovascular risk assessed by SCORE system. Material and methods. A total of 209 subjects aged 40–65 years without clinically overt cardiovascular disease were examined. Parameters of arterial stiffness were obtained by two methods: augmentation index and carotid-radial pulse wave velocity by applanation tonometry and stiffness index by the means of finger photoplethysmography. Flow-mediated dilatation of the brachial artery, reflecting endothelial function, and carotid intima-media thickness was determined using a high-resolution B-mode ultrasonography. Results. Age and the presence of diabetes strongly influenced all parameters of the arterial wall (diabetes was not independent predictor when evaluating augmentation index). Mean arterial pressure and gender were independent predictors for arterial stiffness parameters – carotid-radial pulse wave velocity and augmentation index. Flow-mediated dilatation was strongly dependent on the diameter of the brachial artery, age, and body mass index. Using logistic regression, it was found that pulse wave velocity (P=0.014), intima-media thickness (P=0.004), and flow-mediated dilatation (P=0.020) were important parameters dividing subjects to the groups of increased (³5%) and low (<5%) cardiovascular risk assessed by SCORE system. The cutoff values for intima-media thickness and pulse wave velocity were 0.078 cm and 8.95 m/s, respectively. Conclusions. Arterial wall parameters are closely associated with conventional risk factors; they are influenced by age and the presence of diabetes. Arterial stiffness parameters are also influenced by mean arterial pressure; high-density lipoprotein cholesterol has influence on carotid intima-media thickness. Cutoff values for carotid intima-media thickness and carotid-radial pulse wave velocity could help to discriminate patients with increased cardiovascular risk.

Local carotid stiffness and intima-media thickness assessment by a novel ultrasound-based system in essential hypertension

2012 ◽  
Vol 223 (2) ◽  
pp. 372-377 ◽  
Author(s):  
Chiara Giannarelli ◽  
Elisabetta Bianchini ◽  
Rosa Maria Bruno ◽  
Armando Magagna ◽  
Linda Landini ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Intima Media Thickness ◽  
Media Thickness ◽  
Carotid Stiffness

Assessment of Carotid Stiffness and Intima-Media Thickness From Ultrasound Data

2010 ◽  
Vol 29 (8) ◽  
pp. 1169-1175 ◽  
Author(s):  
Elisabetta Bianchini ◽  
Erwan Bozec ◽  
Vincenzo Gemignani ◽  
Francesco Faita ◽  
Chiara Giannarelli ◽  
...  
Keyword(s):  
Intima Media Thickness ◽  
Media Thickness ◽  
Carotid Stiffness

scholarly journals Anemia in Patients with Axial Spondyloarthritis is Not Associated with an Increase of Arterial Stiffness and Intima-Media Thickness (Results of a Single-Center Cross-Sectional Study)

2021 ◽  
Vol 11 (4) ◽  
pp. 284-291
Author(s):  
K. N. Safarova ◽  
V. I. Makhina ◽  
K. D. Dorogoykina ◽  
A. P. Rebrov
Keyword(s):  
Arterial Stiffness ◽  
Pulse Wave ◽  
Axial Spondyloarthritis ◽  
Augmentation Index ◽  
Subclinical Atherosclerosis ◽  
Intima Media Thickness ◽  
Vascular Wall ◽  
Stiffness Index ◽  
Media Thickness ◽  
Wall Stiffness

Aim: to study parameters of arterial stiffness and subclinical atherosclerosis in patients with axial spondyloarthritis (axSpA) without clinically manifest cardiovascular pathology depending on the presence of anemia.Material and methods. 102 patients with axSpA (mean age – 37.7±9.8 years, axSpA duration – 13.5±8.7 years, 66 (64.7%) men) were included. The BASDAI index and C-reactive protein (CRP)-based ASDAS score were measured, the hemogram, the erythrocyte sedimentation rate (ESR), and the level of CRP were studied. Parameters of arterial stiffness were studied by oscillography and photoplethysmography, intima-media thickness (IMT) was evaluated by B-mode ultrasound according to standard protocols.Results. During analysis of pulse wave properties, no statistically significant differences in parameters of vascular wall stiffness were found in axSpA patients with and without anemia. Aortic pulse wave velocity (PWVao) in patients with anemia was 7.4±1.5 m/sec, aortic augmentation index (Aix-ao) was 19.1±13.7%, stiffness index (SI) was 8.2±1.7 m/sec; in patients without anemia – 7.4±1.4 m/sec, 17.3±10.6% and 8.8±2.0 m/sec, respectively (p >0.05 for all). IMT in patients with anemia was 0.70±0.13 cm, in patients without anemia – 0.73±0.16 cm (p >0.05). Correlation analysis was performed and significant correlations were noted between Aix-ao, PWVao, SI, IMT and age (r=0.488, r=0.516, r=0.289, r=0.461, respectively, p <0.05); Aix-ao, PWVao and the BASDAI index (r=0.243, r=0.253, respectively, p <0.05). Significant correlations between PWVao and Aix-ao (r=0.442, p <0.001), SI (r=0.273, p=0.011) and IMT (r=0.236, p=0.034) were found.Conclusion. The present study did not confirm the negative effect of anemia on vascular wall stiffness parameters and IMT in patients with axSpA. We consider that potential protective effect of anemia, due to well-known pathophysiological patterns — a decrease in blood viscosity and the induction of nitric oxide synthesis, plays an important role. Further studies are required to assess relationship between hemoglobin levels and markers of endothelial dysfunction in patients with axSpA.

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