scholarly journals Quantification of testosterone‐dependent erythropoiesis during male puberty

2021 ◽  
Author(s):  
Erica Mancera‐Soto ◽  
Diana Marcela Ramos‐Caballero ◽  
Jose Magalhaes ◽  
Sandra Chaves Gomez ◽  
Walter F.J. Schmidt ◽  
...  
Keyword(s):  
Male Puberty

Induction of male puberty in patients with hypogonadism hypogonadotrope with subcutaneous gonadotropin

2017 ◽  
Author(s):  
Paloma Moreno-Moreno ◽  
Concepcion Munoz-Jimenez ◽  
Maria Rosa Alhambra-Exposito ◽  
Maria Angeles Galvez-Moreno
Keyword(s):  
Male Puberty

scholarly journals Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

2014 ◽  
Vol 23 (16) ◽  
pp. 4452-4464 ◽  
Author(s):  
Diana L. Cousminer ◽  
Evangelia Stergiakouli ◽  
Diane J. Berry ◽  
Wei Ang ◽  
Maria M. Groen-Blokhuis ◽  
...  
Keyword(s):  
Association Study ◽  
Body Mass ◽  
Sexual Maturation ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Male Puberty ◽  
Genome Wide ◽  
Males And Females

scholarly journals Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Ben Hollis ◽  
◽  
Felix R. Day ◽  
Alexander S. Busch ◽  
Deborah J. Thompson ◽  
...  
Keyword(s):  
Genetic Basis ◽  
Genomic Analysis ◽  
Hair Colour ◽  
Male Puberty ◽  
Shared Genetic

In vitro biological-to-immunological ratio of serum gonadotropins throughout male puberty in children with insulin-dependent diabetes mellitus

Endocrine ◽  
2007 ◽  
Vol 31 (1) ◽  
pp. 18-26 ◽  
Author(s):  
Elisa Nishimura ◽  
Daniela Söderlund ◽  
Cecilia Castro-Fernández ◽  
Teresa Zariñán ◽  
Juan Pablo Méndez ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Dependent Diabetes Mellitus ◽  
Insulin Dependent Diabetes ◽  
Dependent Diabetes Mellitus ◽  
Male Puberty ◽  
Insulin Dependent

scholarly journals Changes in Serum Insulin-Like Factor 3 during Normal Male Puberty

2006 ◽  
Vol 91 (9) ◽  
pp. 3426-3431 ◽  
Author(s):  
Alberto Ferlin ◽  
Andrea Garolla ◽  
Franco Rigon ◽  
Lucia Rasi Caldogno ◽  
Andrea Lenzi ◽  
...  
Keyword(s):  
Leydig Cells ◽  
Prolonged Exposure ◽  
Serum Insulin ◽  
Plasma Concentrations ◽  
Tanner Stage ◽  
Normal Male ◽  
Pubertal Stage ◽  
Cross Sectional ◽  
Male Puberty ◽  
Pubertal Stages

Abstract Context: Insulin-like factor 3 (INSL3) is produced by the Leydig cells, and in adults, its secretion is dependent on the state of differentiation of these cells, which, in turn, is dependent on LH. However, the secretion and regulation of INSL3 during puberty is unknown. Objective: Our objective was to evaluate INSL3 concentrations during normal male puberty and the relation of INSL3 to LH, FSH, and testosterone. Design and Setting: We conducted a cross-sectional study from January to December 2005 at academic clinics. Patients: Participating in the study were 75 healthy male subjects aged 9.5–17.5 yr, homogeneously distributed into five pubertal groups of 15 according to Tanner stages. Main Outcome Measures: We assessed mean testicular volume and LH, FSH, testosterone, and INSL3 concentrations in relation to age and pubertal stage. Results: We observed an increase of INSL3 and LH levels from Tanner stage 2 to 4, and an increase of FSH from stage 2 to 3. Testosterone levels increased from stage 3 to 4. No differences were seen for all measured hormones between stages 4 and 5. The increase in INSL3 seemed therefore to anticipate the increase in testosterone. However, INSL3 plasma concentrations at pubertal stages 4 and 5 are about one fourth of adult levels, whereas FSH, LH, and testosterone reached adult levels by stage 4. Positive significant correlations were found between INSL3 and LH for all pubertal stages. Conclusions: This study provides information on the physiological dynamics of INSL3, showing that the serum concentrations of this hormone increased progressively throughout puberty under the differentiating action of LH on Leydig cells. INSL3 is therefore confirmed to represent a marker of Leydig cell differentiation and function. However, a prolonged exposure to LH seems to be necessary to reach INSL3 concentrations of adults. A possible use of INSL3 in puberty disorders is promising.

Ethanol-induced delayed male puberty in mice is not due to impaired leydig cell function

1989 ◽  
Vol 3 (2) ◽  
pp. 101-113 ◽  
Author(s):  
Robert A. Anderson ◽  
Jack F. Phillips ◽  
Sally H. Berryman ◽  
Lourens J.D. Zaneveld
Keyword(s):  
Leydig Cell ◽  
Cell Function ◽  
Male Puberty ◽  
Leydig Cell Function
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