scholarly journals Nutritional approaches to counter performance constraints in high level sports competition

2021 ◽  
Author(s):  
Louise M Burke
Keyword(s):  
Performance Constraints ◽  
High Level

An Interactive Multimedia Framework for Education on Vehicle Electrification

2013 ◽  
Author(s):  
Michael J. Rothenberger ◽  
Hosam K. Fathy
Keyword(s):  
Electric Vehicles ◽  
Interactive Multimedia ◽  
Hybrid Electric Vehicles ◽  
Vehicle Design ◽  
Societal Factors ◽  
Performance Constraints ◽  
Educational Videos ◽  
High Level ◽  
Pedagogy Literature ◽  
Level Performance

This paper presents an interactive multimedia framework for introducing students to vehicle electrification/hybridization. The framework familiarizes its target audience with: (i) the societal factors driving the development of hybrid and plug-in hybrid electric vehicles (HEVs/PHEVs); (ii) the differences between conventional vehicles, HEVs, and PHEVs; and (iii) the high-level performance constraints and tradeoffs inherent in hybrid vehicle design. The framework consists of two coupled components: (i) a set of educational videos on vehicle electrification; and (ii) a 3D videogame built around physics-based models of conventional and series hybrid ambulances. The paper presents both the above education framework and the specific principles from the pedagogy literature guiding its design.

DEMOCRAT: A DEsign MethOdology for the Conception of Robots with parallel ArchiTecture

Robotica ◽  
1997 ◽  
Vol 15 (4) ◽  
pp. 367-373 ◽  
Author(s):  
J-P. Merlet
Keyword(s):  
Design Methodology ◽  
Parallel Architecture ◽  
Parallel Robots ◽  
Design Solution ◽  
Closed Region ◽  
High Level Language ◽  
Performance Constraints ◽  
High Level

This paper presents a design methodology for parallel robots having to satisfy a set of performance constraints. Some of these constraints are used to compute a closed region in the parameters space (in which a point define an unique robot geometry) which define all the robot geometries fulfilling these constraints. Then a grid is created over this region and for each node of this grid the requirements, expressed in a high level language, are evaluated. The node leading to the robot best fulfilling the constraints is the design solution.

scholarly journals Energy Minimization Under Area and Performance Constraints for Multimedia Applications Realized on Embedded Cores

VLSI Design ◽  
2002 ◽  
Vol 14 (3) ◽  
pp. 273-286
Author(s):  
N. D. Zervas ◽  
K. Masselos ◽  
Y. A. Karayiannis ◽  
C. E. Goutis
Keyword(s):  
Real Life ◽  
Original Description ◽  
Multimedia Applications ◽  
Major Step ◽  
Performance Constraints ◽  
Data Memory ◽  
Embedded Cores ◽  
And Performance ◽  
High Level ◽  
The Impact

A systematic methodology for energy dissipation reduction of multimedia applications realized on architectures based on embedded cores and application specific data memory organization is proposed. Performance and area are explicitly taken into account. The proposed methodology includes two major steps: A high-level code transformation step that reorganizes the original description of the target application. The second major step includes the determination of the processor, memory and bus organization of the system and is briefly described. Experimental results from several real-life demonstrators prove the impact of the high level step of the proposed methodology.

scholarly journals High-Level Design Space and Flexibility Exploration for Adaptive, Energy-Efficient WCDMA Channel Estimation Architectures

2012 ◽  
Vol 2012 ◽  
pp. 1-20 ◽  
Author(s):  
Zoltán Endre Rákossy ◽  
Zheng Wang ◽  
Anupam Chattopadhyay
Keyword(s):  
Channel Estimation ◽  
Software Defined Radio ◽  
High Performance ◽  
Design Guidelines ◽  
Complexity Classes ◽  
Power Performance ◽  
Performance Constraints ◽  
Estimation Algorithms ◽  
Wide Range ◽  
High Level

Due to the fast changing wireless communication standards coupled with strict performance constraints, the demand for flexible yet high-performance architectures is increasing. To tackle the flexibility requirement, software-defined radio (SDR) is emerging as an obvious solution, where the underlying hardware implementation is tuned via software layers to the varied standards depending on power-performance and quality requirements leading to adaptable, cognitive radio. In this paper, we conduct a case study for representatives of two complexity classes of WCDMA channel estimation algorithms and explore the effect of flexibility on energy efficiency using different implementation options. Furthermore, we propose new design guidelines for both highly specialized architectures and highly flexible architectures using high-level synthesis, to enable the required performance and flexibility to support multiple applications. Our experiments with various design points show that the resulting architectures meet the performance constraints of WCDMA and a wide range of options are offered for tuning such architectures depending on power/performance/area constraints of SDR.

Transcription factor/DNA interactions visualized by electron spectroscopic imaging

1992 ◽  
Vol 50 (1) ◽  
pp. 450-451
Author(s):  
David P. Bazett-Jones ◽  
Mark L. Brown
Keyword(s):  
Transcription Factor ◽  
Dna Sequences ◽  
Transcription Initiation ◽  
Molecular Mechanisms ◽  
Phosphorus Content ◽  
Spectroscopic Imaging ◽  
Electron Spectroscopic Imaging ◽  
Dna Backbone ◽  
Two Parameters ◽  
High Level

A multisubunit RNA polymerase enzyme is ultimately responsible for transcription initiation and elongation of RNA, but recognition of the proper start site by the enzyme is regulated by general, temporal and gene-specific trans-factors interacting at promoter and enhancer DNA sequences. To understand the molecular mechanisms which precisely regulate the transcription initiation event, it is crucial to elucidate the structure of the transcription factor/DNA complexes involved. Electron spectroscopic imaging (ESI) provides the opportunity to visualize individual DNA molecules. Enhancement of DNA contrast with ESI is accomplished by imaging with electrons that have interacted with inner shell electrons of phosphorus in the DNA backbone. Phosphorus detection at this intermediately high level of resolution (≈lnm) permits selective imaging of the DNA, to determine whether the protein factors compact, bend or wrap the DNA. Simultaneously, mass analysis and phosphorus content can be measured quantitatively, using adjacent DNA or tobacco mosaic virus (TMV) as mass and phosphorus standards. These two parameters provide stoichiometric information relating the ratios of protein:DNA content.

Advances in Stem Instrumentation for Biology

1990 ◽  
Vol 48 (1) ◽  
pp. 362-363
Author(s):  
J. S. Wall
Keyword(s):  
Scanning Transmission Electron Microscope ◽  
Carbon Films ◽  
Specimen Preparation ◽  
Material Deposition ◽  
Active User ◽  
Percent Improvement ◽  
Scanning Transmission ◽  
The Moment ◽  
Film Substrate ◽  
High Level

The forte of the Scanning transmission Electron Microscope (STEM) is high resolution imaging with high contrast on thin specimens, as demonstrated by visualization of single heavy atoms. of equal importance for biology is the efficient utilization of all available signals, permitting low dose imaging of unstained single molecules such as DNA.Our work at Brookhaven has concentrated on: 1) design and construction of instruments optimized for a narrow range of biological applications and 2) use of such instruments in a very active user/collaborator program. Therefore our program is highly interactive with a strong emphasis on producing results which are interpretable with a high level of confidence.The major challenge we face at the moment is specimen preparation. The resolution of the STEM is better than 2.5 A, but measurements of resolution vs. dose level off at a resolution of 20 A at a dose of 10 el/A2 on a well-behaved biological specimen such as TMV (tobacco mosaic virus). To track down this problem we are examining all aspects of specimen preparation: purification of biological material, deposition on the thin film substrate, washing, fast freezing and freeze drying. As we attempt to improve our equipment/technique, we use image analysis of TMV internal controls included in all STEM samples as a monitor sensitive enough to detect even a few percent improvement. For delicate specimens, carbon films can be very harsh-leading to disruption of the sample. Therefore we are developing conducting polymer films as alternative substrates, as described elsewhere in these Proceedings. For specimen preparation studies, we have identified (from our user/collaborator program ) a variety of “canary” specimens, each uniquely sensitive to one particular aspect of sample preparation, so we can attempt to separate the variables involved.

A Questionnaire Survey of Current Rehabilitation Practices for Adults With Normal Hearing Sensitivity Who Experience Auditory Difficulties

2020 ◽  
Vol 29 (4) ◽  
pp. 738-761
Author(s):  
Tess K. Koerner ◽  
Melissa A. Papesh ◽  
Frederick J. Gallun
Keyword(s):  
Hearing Aids ◽  
Questionnaire Survey ◽  
Patient Population ◽  
Clinical Care ◽  
Normal Hearing ◽  
Auditory Training ◽  
Training Methods ◽  
Hearing Sensitivity ◽  
Considerable Benefit ◽  
High Level

Purpose A questionnaire survey was conducted to collect information from clinical audiologists about rehabilitation options for adult patients who report significant auditory difficulties despite having normal or near-normal hearing sensitivity. This work aimed to provide more information about what audiologists are currently doing in the clinic to manage auditory difficulties in this patient population and their views on the efficacy of recommended rehabilitation methods. Method A questionnaire survey containing multiple-choice and open-ended questions was developed and disseminated online. Invitations to participate were delivered via e-mail listservs and through business cards provided at annual audiology conferences. All responses were anonymous at the time of data collection. Results Responses were collected from 209 participants. The majority of participants reported seeing at least one normal-hearing patient per month who reported significant communication difficulties. However, few respondents indicated that their location had specific protocols for the treatment of these patients. Counseling was reported as the most frequent rehabilitation method, but results revealed that audiologists across various work settings are also successfully starting to fit patients with mild-gain hearing aids. Responses indicated that patient compliance with computer-based auditory training methods was regarded as low, with patients generally preferring device-based rehabilitation options. Conclusions Results from this questionnaire survey strongly suggest that audiologists frequently see normal-hearing patients who report auditory difficulties, but that few clinicians are equipped with established protocols for diagnosis and management. While many feel that mild-gain hearing aids provide considerable benefit for these patients, very little research has been conducted to date to support the use of hearing aids or other rehabilitation options for this unique patient population. This study reveals the critical need for additional research to establish evidence-based practice guidelines that will empower clinicians to provide a high level of clinical care and effective rehabilitation strategies to these patients.

805: High-Level Cyclin D1 is Associated with High Gleason Grade and Predicts Worse Biochemical-Free Survival in Prostate Cancer

2006 ◽  
Vol 175 (4S) ◽  
pp. 260-260
Author(s):  
Rile Li ◽  
Hong Dai ◽  
Thomas M. Wheeler ◽  
Anna Frolov ◽  
Gustavo Ayala
Keyword(s):  
Prostate Cancer ◽  
Cyclin D1 ◽  
Gleason Grade ◽  
Free Survival ◽  
High Level
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