scholarly journals APPLICATION OF GREEN SYNTHESIS OF GOLD NANOPARTICLES: A REVIEW

2018 ◽  
Vol 81 (1) ◽  
Author(s):  
Adamu Ibrahim Usman ◽  
Azlan Abdul Aziz ◽  
Osama Abu Noqta

The field of nanotechnology is advancing rapidly due to its extensive applications in distinct fields of science and technology. Several methods have been used for the production of nanoparticles due to their immense functions in various fields. The limitations of the traditional methods and their toxic nature of the chemicals used during the synthesis or in their application hinder their usage in the biomedical field. This led to the development of the green synthesis of nanoparticles. Researchers have focused on developing simple, cost-effective, clean, non-toxic and eco-friendly procedures for synthesis of nanoparticles. Various biological agents like bacteria, fungi, plant extracts, etc. are used for the green synthesis of metal nanoparticles due to their biocompatibility. The dissolved metals ions are reduced into nano-metals by bio-agent in the green process. The manners and protocols of the green synthesis of gold nanoparticles are presented in this review. Recent literature on green synthesis of noble gold nanoparticles with their various applications in biomedical, antifungal/antibacterial, drug delivery, sensors and photocatalytic have also been discussed.

2021 ◽  
Vol 22 (21) ◽  
pp. 11993
Author(s):  
Ashvi Sanjay Jain ◽  
Pranita Subhash Pawar ◽  
Aira Sarkar ◽  
Vijayabhaskarreddy Junnuthula ◽  
Sathish Dyawanapelly

Among the various types of nanoparticles and their strategy for synthesis, the green synthesis of silver nanoparticles has gained much attention in the biomedical, cellular imaging, cosmetics, drug delivery, food, and agrochemical industries due to their unique physicochemical and biological properties. The green synthesis strategies incorporate the use of plant extracts, living organisms, or biomolecules as bioreducing and biocapping agents, also known as bionanofactories for the synthesis of nanoparticles. The use of green chemistry is ecofriendly, biocompatible, nontoxic, and cost-effective. We shed light on the recent advances in green synthesis and physicochemical properties of green silver nanoparticles by considering the outcomes from recent studies applying SEM, TEM, AFM, UV/Vis spectrophotometry, FTIR, and XRD techniques. Furthermore, we cover the antibacterial, antifungal, and antiparasitic activities of silver nanoparticles.


2016 ◽  
Vol 2016 ◽  
pp. 1-14 ◽  
Author(s):  
Muhammad Imran Din ◽  
Aneela Rani

Green protocols for the synthesis of nanoparticles have been attracting a lot of attention because they are eco-friendly, rapid, and cost-effective. Nickel and nickel oxide nanoparticles have been synthesized by green routes and characterized for impact of green chemistry on the properties and biological effects of nanoparticles in the last five years. Green synthesis, properties, and applications of nickel and nickel oxide nanoparticles have been reported in the literature. This review summarizes the synthesis of nickel and nickel oxide nanoparticles using different biological systems. This review also provides comparative overview of influence of chemical synthesis and green synthesis on structural properties of nickel and nickel oxide nanoparticles and their biological behavior. It concludes that green methods for synthesis of nickel and nickel oxide nanoparticles are better than chemical synthetic methods.


Biomolecules ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 1498
Author(s):  
Rimsha Chaudhary ◽  
Khadija Nawaz ◽  
Amna Komal Khan ◽  
Christophe Hano ◽  
Bilal Haider Abbasi ◽  
...  

Algae have long been exploited commercially and industrially as food, feed, additives, cosmetics, pharmaceuticals, and fertilizer, but now the trend is shifting towards the algae-mediated green synthesis of nanoparticles (NPs). This trend is increasing day by day, as algae are a rich source of secondary metabolites, easy to cultivate, have fast growth, and are scalable. In recent era, green synthesis of NPs has gained widespread attention as a safe, simple, sustainable, cost-effective, and eco-friendly protocol. The secondary metabolites from algae reduce, cap, and stabilize the metal precursors to form metal, metal oxide, or bimetallic NPs. The NPs synthesis could either be intracellular or extracellular depending on the location of NPs synthesis and reducing agents. Among the diverse range of algae, the most widely investigated algae for the biosynthesis of NPs documented are brown, red, blue-green, micro and macro green algae. Due to the biocompatibility, safety and unique physico-chemical properties of NPs, the algal biosynthesized NPs have also been studied for their biomedical applications, which include anti-bacterial, anti-fungal, anti-cancerous, anti-fouling, bioremediation, and biosensing activities. In this review, the rationale behind the algal-mediated biosynthesis of metallic, metallic oxide, and bimetallic NPs from various algae have been reviewed. Furthermore, an insight into the mechanism of biosynthesis of NPs from algae and their biomedical applications has been reviewed critically.


Author(s):  
Moorthy Ganeshkumar ◽  
Thangavel Ponrasu ◽  
Modhugoor Devendiran Raja ◽  
Muthaiya Kannappan Subamekala ◽  
Lonchin Suguna

2018 ◽  
Vol 6 (11) ◽  
pp. 1720
Author(s):  
Shiva Shirotiya ◽  
Bhanumati Singh ◽  
Chauhan V.S.

Nanobiotechnology is a growing field due to its wide variety of applications in many fields of science and technology. Use of Nanoparticles in biomedical and biotechnology is due to its great surface area, improved permeability, retention effect etc. Green synthesized gold nanoparticles are very much useful for different applications in nanobiotechnology because of its properties and ecofriendly nature. Because of its chemical and physical properties, Colloidal gold has different uses in biotechnology. There are many ways to synthesize gold nanoparticles but green synthesis method is more appropriate as compared to others. This review addressed basically on the different methods of synthesis of gold nanoparticles but is also focused on its green synthesis, different shapes, sizes and various applications in each and every field of life. To be concise, AuNPs are potent tool in targeting drug delivery and biomedical application.


Author(s):  
Lavanya Krishnadhas ◽  
Santhi R. ◽  
Annapurani S.

Nanoparticles are gaining interest in biomedical applications due to its importance such as anti-bacterial, anti-fungal and anti-cancer agents. Conventional methods for the synthesis of metal nanoparticles involves toxic reagents which produce harmful by-products and are hazardous to the environment. To overcome these limitations, green synthesis of nanoparticles was established. Eco-friendly methods using plant extracts are gaining popularity due to the abundance of raw materials and the production of non-toxic by-products threatening to the environment. Moreover, the nanoparticles synthesized from the plant extract are cost-effective. In addition, nanoparticles produced by green synthesis methods produces synergetic effect where both the nanoparticles as well as the natural bioactive constituents of the plant influence the biocidal properties. Different methods namely heating in water bath, microwave oven and exposure to bright sunlight were adopted for the synthesis of silver nanoparticles. Plant extract based synthesis of silver nanoparticles was eco-friendly and shows an alternative promise in bio-medical applications and it undertakes the negative effects of synthetic drugs.


Author(s):  
Mani Abirami ◽  
Krishnan Kannabiran

Microbial green synthesis of nanoparticles and exploiting them for biological applications has received considerable attention in the recent past. Gold (Au) nanoparticles were synthesised using Streptomyces ghanaensis sp. VITHM1 (MTCC #12465) biomass and evaluated for its cytotoxic activity. Au NPs were synthesised after 56 h of incubation of cell free supernatant with 1 mM HAuCl4 at room temperature. The synthesized NPs were characterized by UV-visible spectrum, X-ray diffraction (XRD), atomic force microscopy, scanning electron microscopy equipped with energy dispersive spectroscopy, transmission electron microscopy, fourier transform infrared spectroscopy, dynamic light scattering (DLS) and zeta potential. The synthesised gold nanoparticles were highly stable, spherical in shape and the average size was 30-50 nm. The secondary metabolites present in the biomass were identified by gas chromatography-mass spectrometry (GC-MS). The mechanism of formation of gold nanoparticles with the two major secondary metabolites present in the extracted biomass was proposed. The 3D structure of the unit cell in the synthesized nanoparticles was determined by XRD data base. The synthesized gold nanoparticles  (200 µg/mL) exhibited admirable cytotoxic activity by inducing apoptosis in Hep-2 cells after 48 h of incubation. Gold nanoparticles (250 µg/mL) did not cause any haemolysis on human red blood cells. These results of this study suggest that Streptomyces biomass- mediated gold nanoparticles can be explored for cytotoxic activity


2021 ◽  
Vol 7 (2) ◽  
pp. 139 ◽  
Author(s):  
Mahendra Rai ◽  
Shital Bonde ◽  
Patrycja Golinska ◽  
Joanna Trzcińska-Wencel ◽  
Aniket Gade ◽  
...  

Nanotechnology is a new and developing branch that has revolutionized the world by its applications in various fields including medicine and agriculture. In nanotechnology, nanoparticles play an important role in diagnostics, drug delivery, and therapy. The synthesis of nanoparticles by fungi is a novel, cost-effective and eco-friendly approach. Among fungi, Fusarium spp. play an important role in the synthesis of nanoparticles and can be considered as a nanofactory for the fabrication of nanoparticles. The synthesis of silver nanoparticles (AgNPs) from Fusarium, its mechanism and applications are discussed in this review. The synthesis of nanoparticles from Fusarium is the biogenic and green approach. Fusaria are found to be a versatile biological system with the ability to synthesize nanoparticles extracellularly. Different species of Fusaria have the potential to synthesise nanoparticles. Among these, F. oxysporum has demonstrated a high potential for the synthesis of AgNPs. It is hypothesised that NADH-dependent nitrate reductase enzyme secreted by F. oxysporum is responsible for the reduction of aqueous silver ions into AgNPs. The toxicity of nanoparticles depends upon the shape, size, surface charge, and the concentration used. The nanoparticles synthesised by different species of Fusaria can be used in medicine and agriculture.


2021 ◽  
Author(s):  
Gulzar Ahmed Rather ◽  
Anima Nanda ◽  
Arghya Chakravorty ◽  
Saima Hamid ◽  
Johra Khan ◽  
...  

Abstract Nanobiotechnology has been achieved great significance in terms of nanomedicine & many others. But the first challenge in nanobiotechnology science is the preparation of stable nanoparticles. Presently, many preparation methods have been developed like different chemical & physical processes, but the main drawbacks of these processes are required hazardous chemicals, environmental impact, and ultimately expenses a lot. To overcome these challenges another advanced technology has been developed, which is termed green or biogenic synthesis. This review is discussing the modern approaches of the eco-friendly and cost-effective methodology of green synthesis of nanoparticles by using different eukaryotic & prokaryotic agents like plants, human cell lines, diatoms, algae, fungi, bacteria, viruses, and other organisms. Also, this review gives a clear idea of the different applications of those nanoparticles in drug delivery, dentistry, labeling, diagnostics & sensors.


Nativa ◽  
2019 ◽  
Vol 7 (3) ◽  
pp. 268
Author(s):  
Pedro Henrique da Conceição Silva ◽  
Anselmo Fortunato Ruiz Rodriguez

Tradicionalmente as técnicas de síntese de nanopartículas utilizam solventes tóxicos, o que gera resíduos potencialmente nocivos tanto à saúde quanto ao meio ambiente. Buscando metodologias mais sustentáveis na síntese de nanopartículas várias pesquisas têm proposto a utilização de agentes biológicos ou parte deles, em substituição aos reagentes químicos tóxicos. Assim, este trabalho propôs sintetizar nanopartículas de ouro, utilizando síntese verde, ou seja, o látex da planta Sangue de Dragão (Croton lechleri Müll. Arg.) como agente redutor. A planta Sangue de Dragão é nativa dos países Peru e Bolívia, no Brasil ela é encontrada na região Norte, nos estados Rondônia, Acre e Amazonas. Para realizar a síntese de nanopartículas, em busca de condições de síntese e de aperfeiçoamento de parâmetros, utilizou-se a técnica de visão de nanopartículas em suspensão coloidal e estabilidade, com monodispersividade. Obtendo-se monodispersidade das nanopartículas de ouro, sendo formadas nanopartículas que se encontram no diâmetro entre 10 nm e 40 nm. O potencial zeta esteve na faixa de da região de +/- 30 mV, também foi observado que as partículas se agregam com uma dispersão instável, no decorrer do tempo. A síntese verde utilizando o látex da planta Sangue de Dragão apresentou-se resultados compatíveis com as técnicas que utilizam os agentes tóxicos, porem sustentável e com baixo custo para a realização.Palavras-chave: Croton lechleri, nanopartículas de ouro, ressonância plasmônica superficial. SYNTHESIS AND CHARACTERIZATION OF COLOIDAL GOLD NANOPARTICLES WITH LATEX AS A REDUCING AGENT ABSTRACT: Traditionally the techniques of synthesis of nanoparticles use toxic solvents, which generate residues potentially harmful to health and the environment. Looking for more sustainable methodologies in the synthesis of nanoparticles several researches has proposed the use of biological agents or part of them, replacing the toxic chemical reagents. Thus, this work proposed to synthesize gold nanoparticles, using green synthesis, that is, the latex of the Dragon Blood plant (Croton lechleri Müll. Arg.) As a reducing agent. The Dragon Blood plant is native to Peru and Bolivia, in Brazil it is found in the North region, in the states of Rondônia, Acre and Amazonas. To perform the synthesis of nanoparticles, searching for conditions of synthesis and improvement of parameters, the technique of nanoparticle vision in colloidal suspension and stability, with monodispersivity, was used. Obtaining monodispersity of the gold nanoparticles, being formed nanoparticles that are in the diameter between 10 nm and 40 nm. The zeta potential was within the range of +/- 30 mV, it was also observed that the particles aggregate with an unstable dispersion over time. The green synthesis using the latex of the Dragon Blood plant presented results compatible with the techniques that use the toxic agents, but sustainable and with low cost to the realization.Keywords: Croton lechleri, gold nanoparticles, superficial plasmon resonance.


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