Monocyte M1 / M2 profile is altered in paediatric burn patients with hypertrophic scarring

Author(s):  
Helen Williams ◽  
Sasithorn Suda ◽  
Suat Dervish ◽  
Yen Tien Yap ◽  
Andrew J. A. Holland ◽  
...  
1984 ◽  
Vol 5 (3) ◽  
pp. 221-224 ◽  
Author(s):  
Janice C. Judge ◽  
S Randolph May ◽  
Frederick A DeClement

Author(s):  
Derek A. Affonce ◽  
Erik S. Sojka ◽  
Livingston Van De Water ◽  
Robert Sheridan ◽  
Alex J. Fowler

Approximately 100,000 burn patients require hospital admissions each year in the United States. About 90% of those patients survive to face the long term consequences of burn injury [1]. The primary cause of long term disability in burn survivors is hypertrophic scarring. These thick, deforming scars physically impair movement and cause major psychological morbidity. Hypertrophic scarring is particularly severe in young children [2].


2019 ◽  
Author(s):  
V. Borisov ◽  
E. Klychnikova ◽  
E. Tazina ◽  
A. Bogdanova ◽  
M. Kaplunova ◽  
...  

2019 ◽  
Author(s):  
V. Borisov ◽  
M. Platunova ◽  
V. Abramov ◽  
M. Kaplunova

2007 ◽  
Vol 20 (2) ◽  
pp. 158 ◽  
Author(s):  
Hyeong Seok Kim ◽  
Hyun Mook Chang ◽  
Do Young Choi ◽  
Chul Ho Woo ◽  
Sung Ha Mun ◽  
...  

Author(s):  
Elham Abbasi ◽  
Hossein Goudarzi ◽  
Ali Hashemi ◽  
Alireza Salimi Chirani ◽  
Abdollah Ardebili ◽  
...  

AbstractA major challenge in the treatment of infections has been the rise of extensively drug resistance (XDR) and multidrug resistance (MDR) in Acinetobacter baumannii. The goals of this study were to determine the pattern of antimicrobial susceptibility, blaOXA and carO genes among burn-isolated A. baumannii strains. In this study, 100 A. baumannii strains were isolated from burn patients and their susceptibilities to different antibiotics were determined using disc diffusion testing and broth microdilution. Presence of carO gene and OXA-type carbapenemase genes was tested by PCR and sequencing. SDS-PAGE was done to survey CarO porin and the expression level of carO gene was evaluated by Real-Time PCR. A high rate of resistance to meropenem (98%), imipenem (98%) and doripenem (98%) was detected. All tested A. baumannii strains were susceptible to colistin. The results indicated that 84.9% were XDR and 97.9% of strains were MDR. In addition, all strains bore blaOXA-51 like and blaOXA-23 like and carO genes. Nonetheless, blaOXA-58 like and blaOXA-24 like genes were harbored by 0 percent and 76 percent of strains, respectively. The relative expression levels of the carO gene ranged from 0.06 to 35.01 fold lower than that of carbapenem-susceptible A. baumannii ATCC19606 and SDS – PAGE analysis of the outer membrane protein showed that all 100 isolates produced CarO. The results of current study revealed prevalence of blaOXA genes and changes in carO gene expression in carbapenem resistant A.baumannii.


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