Comparison of 2% mepivacaine and a solution of 2% lidocaine/epinephrine administered for median and ulnar nerve blocks in horses with naturally occurring forelimb lameness

2021 ◽  
Author(s):  
Sophie Boorman ◽  
Fred DeGraves ◽  
John Schumacher ◽  
Russel Reid Hanson ◽  
Lindsey H. Boone
Keyword(s):  
Ulnar Nerve ◽  
Nerve Blocks ◽  
Naturally Occurring

Comparison of the effectiveness of circumferential versus non-circumferential spread in median and ulnar nerve blocks. A double-blind randomized clinical trial

2020 ◽  
Vol 45 (5) ◽  
pp. 362-366
Author(s):  
Paula Dieguez-Garcia ◽  
Servando Lopez-Alvarez ◽  
Jorge Juncal ◽  
Ana M Lopez ◽  
Xavier Sala-Blanch
Keyword(s):  
Median Nerve ◽  
Ulnar Nerve ◽  
Motor Block ◽  
Primary Outcome ◽  
Sensory Block ◽  
Nerve Blocks ◽  
Double Blind ◽  
Registration Number ◽  
Tunnel Syndrome ◽  
To Receive

Background and objectivesCircumferential (C) spread of local anesthetic around the nerve is recommended for a successful nerve block. We tested the hypothesis that C spread produces a more complete block than non-circumferential (NC) spread.MethodsWe randomized 124 patients undergoing open carpal tunnel syndrome surgery to receive C or NC spread ultrasound-guided median and ulnar nerve blocks. The primary outcome was the proportion of patients who developed complete sensory block measured at 5, 15 and 30 min. The loss of cold sensation was graded as: 0 (complete block), 1 (incomplete block), or 2 (no block). Secondary outcomes included motor block, nerve swelling and adverse events.ResultsIn group C, complete sensory block at 5 min was 2.4 (95% CI 1.0 to 5.7; p=0.04) times more frequent in the median nerve and 3.0 (95% CI 1.2 to 7.2; p=0.01) times more frequent in the ulnar nerve compared with group C. However, at 15 and 30 min, it was similar between groups. Complete motor block was more frequent in group C than in group NC for both the median nerve: 1.5 (95% CI 1.1 to 2.2; p<0.01) at 15 min, 1.1 (95% CI 1.0 to 1.2; p=0.02) at 30 min, and the ulnar nerve: 1.7 (95% CI 1.2 to 2.6; p<0.01) at 15 min, 1.2 (95% CI 1.0 to 1.4; p<0.01) at 30 min. The incidence of nerve swelling and adverse effects was similar between groups.ConclusionsC spread around the median and ulnar nerves at the level of the antecubital fossa generates more complete sensory and motor blocks compared with NC spread.Trial registration numberEudraCT 2011-002608-34 and NCT01603680

BILATERAL ULNAR NERVE BLOCKS FOR THE EVALUATION OF LOCAL ANAESTHETIC AGENTS

1966 ◽  
Vol 10 (3) ◽  
pp. 278
Author(s):  
J. ALB??RT ◽  
B. L??STR??M ◽  
ROBERT W. VIRTUE
Keyword(s):  
Ulnar Nerve ◽  
Local Anaesthetic ◽  
Nerve Blocks ◽  
Anaesthetic Agents

Buffering mepivacaine with sodium bicarbonate speeds and potentiates analgesia of median and ulnar nerve blocks performed on horses

2019 ◽  
Vol 184 (5) ◽  
pp. 155-155 ◽  
Author(s):  
Lindsey Boone ◽  
John Schumacher ◽  
Fred DeGraves ◽  
Robert Cole
Keyword(s):  
Sodium Bicarbonate ◽  
Ulnar Nerve ◽  
Nerve Block ◽  
Inertial Sensor ◽  
Motion Analysis System ◽  
Separate Study ◽  
Nerve Blocks ◽  
Regional Nerve Block ◽  
Analysis System ◽  
Time To Onset

The objective of this study was to determine if buffering mepivacaine HCL (mepHCl) with sodium bicarbonate (NaHCO3) would significantly decrease the time to onset of analgesia when performing median and ulnar nerve blocks in naturally lame horses. Median and ulnar nerve blocks were performed on the naturally lame limb of nine horses during two separate study periods, with a minimum washout period of three days between study periods. Nerve blocks were performed by administering mepHCl alone or mepHCl mixed with NaHCO3 (nine parts 2 per cent mepHCl to one part 8.4 per cent NaHCO3). Lameness was evaluated objectively using a wireless, inertial, sensor-based, motion analysis system (Lameness Locator) prior to the high regional nerve block and every five minutes following administration of the nerve block for 75 min. Resolution of lameness occurred earlier and was more profound for horses administered median and ulnar nerve blocks performed with mepHCl and NaHCO3 than when these nerve blocks were performed using only mepHCl.

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