Determination of the lateral extent of the subcutaneous wound bed in canine cadavers after closure of skin defects to replicate tumor excision

2020 ◽  
Vol 49 (4) ◽  
pp. 728-735 ◽  
Author(s):  
Devin P. Cunningham ◽  
Owen T. Skinner
2021 ◽  
pp. 106689692199072
Author(s):  
Jingjing Hu ◽  
Kojo R. Rawish ◽  
Mariah Leivo ◽  
Dennis Adams ◽  
Somaye Y. Zare ◽  
...  

When more than one focus of stromal invasion is present in a superficially invasive cervical squamous cell carcinoma (SCC), determination of the tumoral lateral extent/horizontal extension, and hence tumor-nodes-metastases (TNM) staging, can be problematic. In recent years, a diagnostic approach to distinguish multifocal pT1a1 from pT1b cases has gained increased attention. These criteria call for classifying SCC as multifocal when invasive foci are separated by blocks of uninvolved cervical tissues, and/or are located on separated cervical lips in a tumor that is discontinuous, and/or are situated far apart (≥2 mm) from each other. In this study, we assess our experience with multifocal stage pT1a1 cervical SCC that was retrospectively classified as such using these criteria. Slides from the loop electrosurgical excision or conization specimens, comprising 212 pT1a1, 173 pT1a2, and 206 pT1b cases, were reviewed. Twenty-four (11%) of the 212 pT1a1 cases were classified as multifocal after review. The 24 multifocal pT1a1 cases were compared with the 188 unifocal pT1a1 cases regarding a variety of clinicopathologic parameters. Notably, these 2 groups showed no significant differences regarding all parameters that were evaluated, including patient age, recurrence rate, primary tumoral features in the primary excision specimen (rate of positive margins, median depth of stromal invasion, frequency of lymphovascular invasion), and frequency of residual disease in additional excisions. In summary, we demonstrate comparably favorable patient outcomes in both unifocal and multifocal cases of pT1a1 SCC of the cervix, and, accordingly, we conclusively affirm the validity of the aforementioned criteria for establishing multifocality.


Medicine ◽  
2017 ◽  
Vol 96 (48) ◽  
pp. e8978
Author(s):  
Bin Fan ◽  
Jian-Ju Liu ◽  
Bei-Fen Wang ◽  
Ying-Jian Sun ◽  
Guang-Yu Li

Skin Cancer ◽  
2006 ◽  
Vol 21 (2) ◽  
pp. 215-219
Author(s):  
Yasuhiro NAKAMURA ◽  
Xuezhu XU ◽  
Takenori TAKAHASHI ◽  
Fujio OTSUKA

2018 ◽  
Vol 68 (3) ◽  
pp. 445
Author(s):  
O. GAVRIILIDOU (Ο. ΓΑΒΡΙΗΛΙΔΟΥ) ◽  
L. G. PAPAZOGLOU (Λ.Γ. ΠΑΠΑΖΟΓΛΟΥ) ◽  
M. KOUKI (Μ. ΚΟΥΚΗ) ◽  
E. STRANTZIA (Ε. ΣΤΡΑΝΤΖΙΑ) ◽  
M. GIANNOULI (Μ. ΓΙΑΝΝΟΥΛΗ) ◽  
...  

Eight female cats of various breeds and median age of 4.5 years, with cutaneous defects in the limbs and trunk which were managed with axial pattern flaps, are described. Skin defects were caused by trauma or tumor excision. The defects were located in the medial aspect of the thigh in 2 cats, the lateral aspect of the thigh in 2, the left axilla in 2, the sternal and inguinal area in 2 and the dorsolateral abdomen and lumbar region in 1 cat. Totally 9 flaps were used including caudal superficial epigastric flap (4), thoracodorsal flap alone (1) or combined with omentalization (1), elbow fold flap and flank fold flap (2). All flaps survived and small dehiscences were found in 2 cats. All cats were healthy after a median follow up time of 13 months. The use of axial pattern flaps is a very effective method for the coverage of large skin defects in cats.


2017 ◽  
Vol 10 (12) ◽  
pp. 1521-1528
Author(s):  
Sabarish Babu Malli Sadhasivan ◽  
Mohamed Shafiuzama ◽  
Mala Shammi ◽  
Ganne Venkata Sudhakar Rao ◽  
Nitin J D Souza ◽  
...  

2018 ◽  
Vol 54 (4) ◽  
pp. 213-218
Author(s):  
Jacqueline V.J. Cavalcanti ◽  
Sabrina L. Barry ◽  
Otto I. Lanz ◽  
Katherine Barnes ◽  
Julia V. Coutin

ABSTRACT The purpose of this retrospective study was to report the outcomes of 19 dogs and 1 cat undergoing reverse saphenous conduit flap between 1999 and 2016. Reverse saphenous conduit flap was used to treat traumatic wounds and wounds resulting from tumor excision in the hind limb; the majority of cases had medial shearing injuries. All animals had complete flap survival. In five animals (20%), minor donor site dehiscence occurred, which did not require surgery. Other postoperative complications included signs of severe venous congestion in one dog. Reverse saphenous conduit flap is a useful technique to repair skin defects of the distal hind limb.


2007 ◽  
pp. S99-S105
Author(s):  
J Růžička ◽  
P Nový ◽  
F Vávra ◽  
L Bolek ◽  
J Beneš

This paper presents a new method for the determination of the volume, surface area and depth of skin defects. The method is based on the description of a spatial defect using a pyramid (made, for example, from injection needles), which is placed over the defect. The projection of the pyramid on to the defect is photographed using a digital camera and subsequently compared with the projection of the same pyramid on to a sheet of grid paper. The defect is mathematically reconstructed on a computer, and an optimal body shape describing the defect is found, using a number of simplifications and assumptions. The method was then validated using a plaster mold of a real foot with 19 defects simulating real wounds. These plaster wounds were molded using alginate hydrocolloid, and the volume, surface area and depth were measured and compared with the results of the pyramid projection by means of regression analysis.This method correlates in all variables with correlation coefficients higher than 0.9. It can be concluded that the projection pyramid method correlates well with the reference mold method and can be used with good results for a whole range of variables.


2009 ◽  
Vol 28 (3) ◽  
pp. 312-317 ◽  
Author(s):  
Paul Thompson ◽  
Jim Jason Hartman ◽  
Muhammad Anun Anung Anandito ◽  
Dhananjay Kumar ◽  
Jim Magill ◽  
...  

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