Comparison of initial leak pressures after single‐ and double‐layer cystotomy closure with barbed and nonbarbed monofilament suture material in an ex vivo ovine model

2019 ◽  
Vol 48 (3) ◽  
pp. 424-430 ◽  
Author(s):  
Daniel J. Duffy ◽  
Cameron G. Kindra ◽  
George E. Moore
Keyword(s):  
Double Layer ◽  
Suture Material ◽  
Ex Vivo ◽  
Ovine Model ◽  
Monofilament Suture

An ex vivo ruminal ovine model to study the immediate immune response in the context of bacterial lipopolysaccharide

2018 ◽  
Vol 18 (3) ◽  
pp. 277-285 ◽  
Author(s):  
Fathi Abouhajer ◽  
Saeed El-Ashram ◽  
Musafiri Karama ◽  
Shujian Huang ◽  
Jian-Feng Liu
Keyword(s):  
Immune Response ◽  
Ex Vivo ◽  
Bacterial Lipopolysaccharide ◽  
Ovine Model

scholarly journals Tensile Strength of Flexor Tendon Repair Using Barbed Suture Material in a Dynamic Ex Vivo Model

2016 ◽  
Vol 04 (01) ◽  
pp. 16-20 ◽  
Author(s):  
Philip Zeplin ◽  
M. Henle ◽  
R. Zahn ◽  
R. Meffert ◽  
K. Schmidt
Keyword(s):  
Tensile Strength ◽  
Suture Material ◽  
Flexor Tendon ◽  
Ex Vivo ◽  
Tendon Repair ◽  
Barbed Suture ◽  
Ex Vivo Model ◽  
Flexor Tendon Repair

Ex vivo ovine model for pediatric flexible endoscopy training

2015 ◽  
Vol 79 (12) ◽  
pp. 2196-2199 ◽  
Author(s):  
Glenn Isaacson ◽  
David C. Ianacone ◽  
Marla R. Wolfson
Keyword(s):  
Ex Vivo ◽  
Flexible Endoscopy ◽  
Ovine Model ◽  
Endoscopy Training

scholarly journals The Absorbable Monofilament Suture Material in the Low Pressure Circulatory System.

1996 ◽  
Vol 25 (3) ◽  
pp. 170-174
Author(s):  
Takao Togo ◽  
Tomohiro Ito ◽  
Kenji Ohsaka ◽  
Sadayuki Murata ◽  
Masaki Hata ◽  
...  
Keyword(s):  
Suture Material ◽  
Circulatory System ◽  
Low Pressure ◽  
Monofilament Suture

scholarly journals Single Layer Versus Double Layer Anastomosis of Small Intestine – A Comparative Study from Karnataka, India

2021 ◽  
Vol 10 (30) ◽  
pp. 2300-2304
Author(s):  
Tejaswini Murari Pawar ◽  
Ravikiran Hosur Ramamurthy ◽  
Shashirekha Chikkavenkataswamy Anjaneyulu
Keyword(s):  
Hospital Stay ◽  
Double Layer ◽  
Suture Material ◽  
Intestinal Anastomosis ◽  
Single Layer ◽  
Absorbable Suture ◽  
Duration Of Hospital Stay ◽  
Absorbable Suture Material ◽  
Significant Difference ◽  
Layer Technique

BACKGROUND Intestinal anastomosis is an operative procedure that is of importance in the practice of surgery. It is a very commonly performed technique in today’s surgical era. We wanted to study the postoperative complications like anastomotic leak and abscess formation and duration of hospital stay in single layer and double layer anastomosis and compare the same. METHODS In our prospective observational study, 80 patients were reviewed and were divided into 2 groups. Cases were allotted to either group based on the odd even method requiring single- and double-layer anastomosis, odd being single layer and even being double layer anastomosis. Intestinal anastomosis was carried out in single layer technique with delayed absorbable suture material and double layer technique with inner transmural layer with delayed absorbable suture material and seromuscular layer with non-absorbable suture material. RESULTS Each group had 40 patients, there was significant difference noted between the groups. Mean duration of hospital stay in single layer group was 17.85 ± 7.62 days and in double layer group was 26.20 ± 16.12 days (P = 0.043 *). In single group, mean time taken for anastomosis was 18.50 ± 1.73 and in double group was 29.05 ± 2.19. There was significant difference in time taken between two groups (P < 0.001). In single group, majority of subjects had no anastomotic Leak (95 %) and 5 % had leak. In double group 70 % had no leak and 30 % had leak. P value was statistically significant (P = 0.037). CONCLUSIONS Single layer anastomosis was better in terms of duration of hospital stay, postoperative anastomotic leaks and time taken for anastomosis. KEY WORDS Single Layer, Double Layer, Small Bowel, Duration of Hospital Stay, Anastomotic Leaks

Abstract 17116: Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_1) ◽  
Author(s):  
Jonathon P Fanning ◽  
Nchafatso G Obonyo ◽  
John-Paul Tung ◽  
Liam Byrne ◽  
Gabriela Simonova ◽  
...  
Keyword(s):  
Septic Shock ◽  
Troponin I ◽  
Ex Vivo ◽  
Venous Pressure ◽  
Haemodynamic Monitoring ◽  
Ovine Model ◽  
Storage Duration ◽  
Cardiovascular Stress ◽  
Endotoxemic Shock ◽  
And Storage

Introduction: Packed red blood cell (PRBC) transfusion in septic shock is generally reserved as a last resort hemodynamic resuscitative measure or for haemoglobin less than 7.0 g/dL. Ex-vivo preservation and storage predispose PRBCs to biochemical / mechanical changes whose impact in a septic host is unknown. This randomised pre-clinical trial specifically evaluates select markers of cardiovascular stress in an ovine model of endotoxemic shock receiving either fresh or stored blood. Methods: Twenty six anesthetised and mechanically ventilated merino ewes were randomly divided into endotoxemic shock (n = 16) or healthy (n = 10) groups. Endotoxemic shock was induced over 4 hours by infusing an escalating dose (total 11.25 mcg / kg) of lipopolysaccharide, LPS ( E.coli 055:B5 ). During the last hour of LPS infusion, 10 mls / kg of either fresh, ≤ 5 days (n = 8) or stored, ≥ 30 days (n = 8) ovine packed PRBCs were administered. Healthy ewes received either fresh, ≤ 5 days (n = 5) or stored, ≥ 30 days (n = 5) ovine PRBCs at corresponding time points. Invasive haemodynamic monitoring and serial echocardiographic assessments were performed in all. Blood samples were measured for cardiac troponin I (cTnI), atrial natriuretic peptide (ANP) and hyaluronan at baseline (T0), 1, 3, 4, 5, 10 and 16h after which the ewes were euthanized. Results: Stored versus fresh PRBCs produced raised hyaluronan levels (P < 0.001) from T3 onwards in both sepsis and healthy groups and resulted in significant (P < 0.001) adverse haemodynamic changes (cardiac index, central venous pressure, pulmonary artery pressure and mixed venous oxygen saturation). Elevated ANP was observed between T3 to T10 (P < 0.001) in septic compared to healthy ewes but there was no association with age of PRBCs. No statistical differences were observed between groups for TnI. Conclusions: Sepsis and storage duration of PRBCs are associated with increased cardiovascular stress suggesting that stored PRBCs may predispose patients with septic shock to poor clinical outcomes.

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