A randomized study of a best practice alert for platelet transfusions

Vox Sanguinis ◽  
2021 ◽  
Author(s):  
Colin Murphy ◽  
Eric Mou ◽  
Emily Pang ◽  
Lisa Shieh ◽  
Jason Hom ◽  
...  
2018 ◽  
Vol 122 (9) ◽  
pp. 1574-1577 ◽  
Author(s):  
Adam Fleddermann ◽  
Steve Jones ◽  
Sarah James ◽  
Kevin F. Kennedy ◽  
Michael L. Main ◽  
...  

2020 ◽  
Vol 11 ◽  
pp. 147-159
Author(s):  
Pushkar Singh Raikhola ◽  
Krishna Prasad Pathak ◽  
Tara Gaire

The aim of this review was to synthesize the aggregated studies aimed at improving health care knowledge, detection practices and management of dementia among healthcare professionals (HPs). Healthcare professionals play a key role in the detection and management of dementia. However, there is a gap in the literature as to what represents best practice with regard to educating HPs in this area. We searched citation index Google scholar, Scopus and Pub Med, Medline, were searched for relevant articles from 2000-2019 without data limit. Inclusion criteria were (1) intervention studies aimed at improving HPs practices concerning dementia care (2) the educational intervention focused on knowledge, detection practice and management of dementia, and (3) peer-reviewed and written in English. Of 4968 articles identified, only 13 articles (six GPs, two clinical/organization care based, one nurse, one physician and affiliated staff and one with physician, manager and therapists based studies) were suitable for inclusion and these all were from developed countries. Seven studies were randomized controlled trials (RCTs), 1 prospective, 2 GPs and supervisors intervention, 1 cohort study, and 2 clinical /organizational care services clustered randomized study. Overall, the methodological quality of these studies was poor, particularly with regard to the methods utilized and sample sizes however, combined programs of, practice based workshops with community and multi-faced educational program were the most effective. The continuous educational intervention program can improve the health professionals’ diagnosis and management knowledge, confidents and negative perception of dementia. HPs should be Interventions Aimed at Improving Knowledge, Detection Practices and Management of Dementia among Health Professionals. Dr. Pushkar Singh Raikhola1 Dr. Krishna Prasad Pathak2 Tara Gaire3 1 Monitoring Directorate, Tribhuban University, Nepal 2 Nepal Open University, Nepal. Alzheimer Related Dementia Society Nepal. 3 Department of Nursing, Innovative health science college THE SAPTAGANDAKI JOURNAL 2055 B.S. Review Article148 The Saptagandaki Journal / Vol.Xi / Issue 11/ November 2020 / ISSN 2594-3243 (Print) supported to improve their knowledge, tackle behavioral problems associated with dementia, be made aware of services and be enabled to engage in more early diagnosis in primary care. Further intervention program should address the cultural change to facilitate long term improvements. Educational intervention program is crucial to the health professionals to get close to the diagnostic confidence.


Blood ◽  
1983 ◽  
Vol 62 (2) ◽  
pp. 473-479 ◽  
Author(s):  
J Gmur ◽  
A von Felten ◽  
B Osterwalder ◽  
H Honegger ◽  
A Hormann ◽  
...  

Abstract A randomized study was performed in 54 thrombocytopenic patients with acute leukemia. Alloimmunization of recipients of random multiple-donor platelet concentrates (MD group) was compared to that of patients receiving random single-donor platelets (SD group). In the SD patients, formation of alloantibodies (mostly anti-HLA) occurred less frequently (p less than 0.002), after a longer time period (p less than 0.002), and after a higher number of transfusions (p less than 0.005) as compared to MD patients. SD patients also became refractory to random platelets less frequently (p less than 0.005), after a longer time period, and after a higher number of transfusions (p less than 0.02). In SD patients, the increments after the first and the last transfusion were in the same range, whereas in MD patients, the 1-hr (p less than 0.001) and the 24-hr (p less than 0.025) increments decreased from the first to the last transfusion. Thus, the use of random SD platelet transfusions postponed alloimmunization.


2015 ◽  
Vol 126 (2) ◽  
pp. 333-337 ◽  
Author(s):  
Jamie L. Morgan ◽  
Sangameshwar R. Baggari ◽  
Wendy Chung ◽  
Julia Ritch ◽  
Donald D. McIntire ◽  
...  

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