scholarly journals Transfusion of 28-day-old leucoreduced or non-leucoreduced stored red blood cells induces an inflammatory response in healthy dogs

Vox Sanguinis ◽  
2013 ◽  
Vol 105 (4) ◽  
pp. 319-327 ◽  
Author(s):  
M. B. Callan ◽  
R. T. Patel ◽  
A. H. Rux ◽  
S. Bandyopadhyay ◽  
A. N. Sireci ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Healthy Dogs

Nucleated red blood cells after cardiopulmonary bypass in infants and children: is there a relationship to the systemic inflammatory response syndrome?

Perfusion ◽  
1999 ◽  
Vol 14 (3) ◽  
pp. 173-180 ◽  
Author(s):  
Bernhard Frey ◽  
Trevor Duke ◽  
Stephen B Horton
Keyword(s):  
Cardiopulmonary Bypass ◽  
Systemic Inflammatory Response Syndrome ◽  
Inflammatory Response ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Systemic Inflammatory Response ◽  
Infants And Children ◽  
Retrospective Case ◽  
Nucleated Red Blood Cells ◽  
Age Range

In a retrospective case control study we aimed to evaluate whether infants and children with nucleated red blood cells (NRBCs) in their peripheral blood smears after cardiopulmonary bypass (CPB) had longer bypass times than controls without NRBCs. On review of a 3-year period, 58 children with NRBCs after CPB (and without NRBCs prior to CPB) were identified (cases). A random sample of 100 children without NRBCs after CPB over the same period served as controls. The median age (range) of the children with NRBCs and without NRBCs was 0.6 years (2 days to 20 years) and 1.4 years (2 days to 16 years), respectively ( p = 0.03). The children with NRBCs had a significantly longer bypass time than the controls (mean, standard deviation (SD): 114 min, 50 vs 79 min, 46 min; p < 0.0001). For the patients with postoperative polychromasia alone, the mean CPB time (111 min, SD 46 min) was also significantly longer than the respective time in the controls ( p < 0.001). Markers of organ dysfunction (renal failure, use of inotropic support, time of endotracheal intubation, stay in intensive care unit and stay in hospital) were significantly more frequent/longer in the NRBC group. Post-CPB release of NRBCs is associated with longer CPB time. This alteration may be part of the CPB-related systemic inflammatory response syndrome.

Anti-inflammatory activity of Buchholzia coriacea Engl. (Capparaceae) leaf extract: evaluation of components of the inflammatory response involved

2015 ◽  
Vol 12 (2) ◽  
Author(s):  
Adaobi C. Ezike ◽  
Collins A. Onyeto ◽  
Ifeoma A. Nwabunike ◽  
Florence N. Mbaoji ◽  
Blessing E. Attah ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Inflammatory Response ◽  
Red Blood Cells ◽  
Vascular Permeability ◽  
Blood Cells ◽  
Leaf Extract ◽  
Inflammatory Activity ◽  
Hypotonic Solution ◽  
Leukocyte Counts ◽  
Anti Inflammatory

Abstract: Earlier studies in our laboratory demonstrated the anti-inflammatory activity of: The effects of methanol leaf extract of: The extract (200 and 400 mg/kg) inhibited acetic acid-induced increase in vascular permeability in a non-dose-related manner and significantly (p<0.05) reduced the total and differential leukocyte counts, respectively, in a dose-related manner. It also significantly (p<0.05) inhibited complement-induced hemolysis of sheep red blood cells (40–72 %) and moderately inhibited heat- (6 %) and hypotonic solution-(24 %) induced hemolysis: Results demonstrated that the anti-inflammatory activity of

Clinical outcome and inflammatory response after transfusion of washed and unwashed red blood cells in children following cardiovascular surgery

2017 ◽  
Vol 47 ◽  
pp. 73-79
Author(s):  
Christine Busch ◽  
Constanze Pfitzer ◽  
Sonja Raschzok ◽  
Oliver Miera ◽  
Felix Berger ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Inflammatory Response ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Cardiovascular Surgery

scholarly journals ЗМІНИ ВЛАСТИВОСТЕЙ ЕРИТРОЦИТІВ У СОБАК

2016 ◽  
Vol 18 (3(71)) ◽  
pp. 3-6
Author(s):  
M.V. Anforova ◽  
V.I. Golovakha ◽  
O.V. Piddubnyak ◽  
M.J. Tyshkivskyy
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Lipid Membranes ◽  
Acid Resistance ◽  
Small Animals ◽  
Hemoglobin Content ◽  
Population Composition ◽  
Rapid Destruction ◽  
Healthy Dogs ◽  
Composition Changes

One of the most important indicators is the assessment of erythroсytopoezis is acid resistance of erythrocytes and their population composition. Changes in these parameters are the most studied in humans, cattle and horses. In small animals, including dogs, the issue is not highlighted enough. Therefore, the study of changes of erytroсytopoezis by using these tests is important. The study erythroсytopoezis parameters was performed in dogs of all ages (1.5–year, 3 – 6 years and 7 and older years of age). It was found that in clinically healthy dogs generall erythroсytopoezis indicators (total number of red blood cells, hemoglobin content, hematocrit value, the index «red» blood – МСН and МСV), regardless of age, did not significantly change. Yet in dogs older than 7 years there were found some changes on the the part of erythroсytopoezis. This was pointed by the changes of the population composition of red blood cells and their acid resistance. In particular, the animals showed an increased number of «old» populations of red blood cells and some changes of their hemolytic resistance. Particularly, the height of the erytrohram peak was 15% higher than in younger animals. The very peak was sharp, indicating the rapid destruction of the «young» red cells and degeneration of their lipid membranes. 

Leukoreduction of Packed Red Blood Cells Prior to Storage Attenuates the Inflammatory Response Following Hemorrhagic Shock and Resuscitation

2014 ◽  
Vol 186 (2) ◽  
pp. 580
Author(s):  
J.M. Sutton ◽  
J.R. Richter ◽  
T.A. Johannigman ◽  
R.M. Schuster ◽  
A.B. Lentsch ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Hemorrhagic Shock ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Packed Red Blood Cells

scholarly journals Blood Morphology in Dogs with Dirofilariasis

2020 ◽  
Vol 210 ◽  
pp. 06006
Author(s):  
Roman Slobodyanik ◽  
Svetlana Zykova ◽  
Larisa Belova ◽  
Andrey Kryazhev
Keyword(s):  
Platelet Count ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Significant Contribution ◽  
Infected Animal ◽  
Lower Boundary ◽  
Significant Difference ◽  
Blood Morphology ◽  
Healthy Dogs ◽  
Morphology Parameters

The article addresses the results of a study of blood morphology parameters in healthy dogs vs. dogs diagnosed with dirofilariasis. In the group of infected animals, the most significant difference was 4.9 higher granulocytes. Another significant contribution is eosinophils and, to a lesser extent, neutrophils and monocytes. In blood of infected and healthy animals, no difference was found in terms of the count of red blood cells, haemoglobin, and haematocrit. Anisocytosis value in red blood cells is probably related to the compensated processes, and differs insignificantly between healthy and infected animal groups. Blood morphology of infected animals is characterized by mild reticulocytosis, not exceeding 20% of physiological norm. In the group of infected dogs, platelet count corresponds to the lower boundary of physiological norm. In healthy animals’ group, platelets and platelet crit is physiologically normal. Leukopenia, lymphocytopenia are detected. Apparently, the reason behind the findings is age of the animals and degree of their adaptation to the progress of the invasive process.

Hemoglobin crystals of the red blood cells in the human renal cortex: electron microscopic observations of the renal lithiasis

1978 ◽  
Vol 36 (2) ◽  
pp. 480-481
Author(s):  
Kosuke Ueda ◽  
Hiroto Washida ◽  
Nakazo Watari
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Renal Cortex ◽  
Uranyl Acetate ◽  
Osmic Acid ◽  
Renal Lithiasis ◽  
Electron Microscopic ◽  
Hemoglobin C ◽  
First Case ◽  
Ultrathin Sections

IntroductionHemoglobin crystals in the red blood cells were electronmicroscopically reported by Fawcett in the cat myocardium. In the human, Lessin revealed crystal-containing cells in the periphral blood of hemoglobin C disease patients. We found the hemoglobin crystals and its agglutination in the erythrocytes in the renal cortex of the human renal lithiasis, and these patients had no hematological abnormalities or other diseases out of the renal lithiasis. Hemoglobin crystals in the human erythrocytes were confirmed to be the first case in the kidney.Material and MethodsTen cases of the human renal biopsies were performed on the operations of the seven pyelolithotomies and three ureterolithotomies. The each specimens were primarily fixed in cacodylate buffered 3. 0% glutaraldehyde and post fixed in osmic acid, dehydrated in graded concentrations of ethanol, and then embedded in Epon 812. Ultrathin sections, cut on LKB microtome, were doubly stained with uranyl acetate and lead citrate.

Sign in / Sign up

Export Citation Format

Share Document