The effects of topical parasympatholytic drugs on pupil diameter and intraocular pressure in healthy dogs treated with 0.005% latanoprost

2015 ◽  
Vol 19 (6) ◽  
pp. 464-472 ◽  
Author(s):  
Nili Kahane ◽  
Hilli Raskansky ◽  
Tali Bdolah-Abram ◽  
Ron Ofri
Keyword(s):  
Intraocular Pressure ◽  
Pupil Diameter ◽  
Healthy Dogs

Comparison of intraocular pressure and pupil diameter after sedation with either acepromazine or dexmedetomidine in healthy dogs

2018 ◽  
Vol 45 (5) ◽  
pp. 667-672 ◽  
Author(s):  
Fabiana Micieli ◽  
Ludovica Chiavaccini ◽  
Barbara Lamagna ◽  
Giancarlo Vesce ◽  
Bruna Santangelo
Keyword(s):  
Intraocular Pressure ◽  
Pupil Diameter ◽  
Healthy Dogs

scholarly journals Effects of tramadol on tear production, intraocular pressure, and pupil size in dogs: clinical study

2015 ◽  
Vol 45 (4) ◽  
pp. 724-729 ◽  
Author(s):  
Thaís Ruiz ◽  
Thalita Priscila da Silva Peres ◽  
Wilma Neres da Silva Campos ◽  
Eveline da Cruz Boa Sorte ◽  
Alexandre Pinto Ribeiro
Keyword(s):  
Intraocular Pressure ◽  
Repeated Measures ◽  
Pupil Diameter ◽  
Keratoconjunctivitis Sicca ◽  
Applanation Tonometry ◽  
Tramadol Hydrochloride ◽  
Tear Production ◽  
Schirmer Tear Test ◽  
Healthy Dogs ◽  
To Receive

This study aimed to evaluate the effects of tramadol on tear production, intraocular pressure (IOP) and pupil diameter (PD) in healthy dogs. Dogs were randomly assigned to receive 4mg kg-1 (n=11) and 6mg kg-1 (n=11) of tramadol hydrochloride intramuscularly. Tear production (Schirmer tear test, STT-1), IOP (applanation tonometry) and the PD (electronic pachymetry) were assessed before, 30 and 60 minutes after administration of tramadol. Data were compared by analysis of variance for repeated measures (P<0.05). Parameters evaluated before, at 30 and 60min, in dogs treated with 4 and 6mg kg-1, were respectively: (STT-1) 22.50±3.38, 21.14±3.94 and 21.09±2.99mm min-1; and 23.05±3.73,22.64±3.76 and 22.82±3.25mm min-1. (IOP) 18.14±2.68, 17.68±2.59 and 18.23±3.84mmHg; and 19.05±2.27, 18.91±2.74 and 17.64±2.34mmHg. (PD) 6.71±0.65, 7.22±1.42 and 6.90±1.39mm; and 6.25±1.08, 6.80±1.27 and 6.49±0.90mm. All parameters evaluated did not change significantly among time points and dose regimen. Based on the conditions under which the experiments were conducted, tramadol did not affect tear production, IOP and PD in dogs, and could be used as a preoperative analgesic for intraocular surgery and pain control for any cause in patients affected by uveitis, glaucoma and keratoconjunctivitis sicca

scholarly journals Effects of dorzolamide/timolol and tafluprost on intraocular pressure and pupil diameter in healthy dogs

2017 ◽  
Vol 47 (9) ◽  
Author(s):  
Nathalie Moro Bassil Dower ◽  
Alexandre Pinto Ribeiro ◽  
Camila do Espirito Santo Maciel ◽  
Paulo Roberto Spiller ◽  
Geovanna Barreira Monteiro ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Treatment Period ◽  
Fixed Combination ◽  
Pupil Diameter ◽  
Cumulative Effect ◽  
Treatment Phase ◽  
Post Treatment ◽  
Healthy Dogs

ABSTRACT: This study aimed to evaluate and compare the effects of the fixed combination of dorzolamide/timolol with those of tafluprost on intraocular pressure (IOP) and pupil diameter (PD) in healthy dogs (n=10). Two experiments were conducted with an interval of 30 days. In both, IOP and PD were assessed at 8, 11, 14, 17, and 20h. Parameters were evaluated during baseline, treatment period of four days, and one day of post-treatment. During treatment phase, IOP decreased by 0.74 (P<0.05), 1.88 (P<0.01), 2.94 (P<0.001), and 3.10mmHg (P<0.01), in dorzolamide/timolol-treated eyes; and by 1.50, 2.18, 2.14, and 2.18mmHg (P<0.001), in tafluprost-treated eyes. PD decreased by 0.24 (P<0.01), 0.32 (P<0.01), 0.49 (P<0.001), and 0.40mm (P<0.001), in dorzolamide/timolol treated eyes; and by 2.31, 2.55, 2.43, and 2.70mm (P<0.001), in tafluprost-treated eyes. Dorzolamide/timolol and tafluprost were able to decrease IOP and PD in healthy dogs. However, a cumulative effect of the fixed combination of dorzolamide/timolol was more effective in reducing IOP, than tafluprost. Comparisons between treatments showed that tafluprost was more effective in reducing PD throughout the treatment phase.

Effects of different mydriatics on intraocular pressure, pupil diameter, and ruminal and intestinal motility in healthy sheep

2013 ◽  
Vol 17 (6) ◽  
pp. 397-402 ◽  
Author(s):  
Alexandre P. Ribeiro ◽  
Roberta M. Crivelaro ◽  
Pedro Paulo M. Teixeira ◽  
Dunia Y. Trujillo ◽  
Patrícia J. Guimarães ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Intestinal Motility ◽  
Pupil Diameter ◽  
Healthy Sheep

The effects of ketamine hydrochloride and diazepam on the intraocular pressure and pupil diameter of the dog’s eye

2012 ◽  
Vol 16 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Liga Kovalcuka ◽  
Edite Birgele ◽  
Dace Bandere ◽  
David L. Williams
Keyword(s):  
Intraocular Pressure ◽  
Pupil Diameter ◽  
Ketamine Hydrochloride

Morphine-Induced Reduction of Intraocular Pressure and Pupil Diameter: Role of Nitric Oxide

Pharmacology ◽  
2006 ◽  
Vol 77 (1) ◽  
pp. 17-24 ◽  
Author(s):  
Juanita Dortch-Carnes ◽  
Karen R.M. Russell
Keyword(s):  
Nitric Oxide ◽  
Intraocular Pressure ◽  
Pupil Diameter
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