Retrospective evaluation of the use of hydrocortisone for treatment of suspected critical illness–related corticosteroid insufficiency (CIRCI) in dogs with septic shock (2010–2017): 47 cases

2021 ◽  
Author(s):  
April M. Summers ◽  
Christine Culler ◽  
Page E. Yaxley ◽  
Julien Guillaumin
Keyword(s):  
Septic Shock ◽  
Critical Illness ◽  
Retrospective Evaluation ◽  
Corticosteroid Insufficiency

scholarly journals Hydrocortisone therapy in a cat with vasopressor-refractory septic shock and suspected critical illness-related corticosteroid insufficiency

2017 ◽  
Vol 5 (7) ◽  
pp. 1123-1129 ◽  
Author(s):  
Simone R. R. Pisano ◽  
Judith Howard ◽  
Horst Posthaus ◽  
Alan Kovacevic ◽  
Ivayla D. Yozova
Keyword(s):  
Septic Shock ◽  
Critical Illness ◽  
Refractory Septic Shock ◽  
Corticosteroid Insufficiency

Prognostic Significance of Different Subgroup Classifications of Critical Illness-Related Corticosteroid Insufficiency in Patients With Septic Shock

Shock ◽  
2011 ◽  
Vol 36 (4) ◽  
pp. 345-349 ◽  
Author(s):  
So Yeon Lim ◽  
Yong Soo Kwon ◽  
Maeng Real Park ◽  
Seo Goo Han ◽  
Kyeongman Jeon ◽  
...  
Keyword(s):  
Septic Shock ◽  
Critical Illness ◽  
Prognostic Significance ◽  
Corticosteroid Insufficiency

scholarly journals Healthcare trajectories before and after critical illness: population-based insight on diverse patients clusters

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Youenn Jouan ◽  
Leslie Grammatico-Guillon ◽  
Noémie Teixera ◽  
Claire Hassen-Khodja ◽  
Christophe Gaborit ◽  
...  
Keyword(s):  
Septic Shock ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Critical Illness ◽  
Length Of Stay ◽  
Population Based ◽  
Hospital Length Of Stay ◽  
Healthcare Use ◽  
Icu Admission ◽  
Icu Discharge

Abstract Background The post intensive care syndrome (PICS) gathers various disabilities, associated with a substantial healthcare use. However, patients’ comorbidities and active medical conditions prior to intensive care unit (ICU) admission may partly drive healthcare use after ICU discharge. To better understand retative contribution of critical illness and PICS—compared to pre-existing comorbidities—as potential determinant of post-critical illness healthcare use, we conducted a population-based evaluation of patients’ healthcare use trajectories. Results Using discharge databases in a 2.5-million-people region in France, we retrieved, over 3 years, all adult patients admitted in ICU for septic shock or acute respiratory distress syndrome (ARDS), intubated at least 5 days and discharged alive from hospital: 882 patients were included. Median duration of mechanical ventilation was 11 days (interquartile ranges [IQR] 8;20), mean SAPS2 was 49, and median hospital length of stay was 42 days (IQR 29;64). Healthcare use (days spent in healthcare facilities) was analyzed 2 years before and 2 years after ICU admission. Prior to ICU admission, we observed, at the scale of the whole study population, a progressive increase in healthcare use. Healthcare trajectories were then explored at individual level, and patients were assembled according to their individual pre-ICU healthcare use trajectory by clusterization with the K-Means method. Interestingly, this revealed diverse trajectories, identifying patients with elevated and increasing healthcare use (n = 126), and two main groups with low (n = 476) or no (n = 251) pre-ICU healthcare use. In ICU, however, SAPS2, duration of mechanical ventilation and length of stay were not different across the groups. Analysis of post-ICU healthcare trajectories for each group revealed that patients with low or no pre-ICU healthcare (which represented 83% of the population) switched to a persistent and elevated healthcare use during the 2 years post-ICU. Conclusion For 83% of ARDS/septic shock survivors, critical illness appears to have a pivotal role in healthcare trajectories, with a switch from a low and stable healthcare use prior to ICU to a sustained higher healthcare recourse 2 years after ICU discharge. This underpins the hypothesis of long-term critical illness and PICS-related quantifiable consequences in healthcare use, measurable at a population level.

Critical Illness–Related Corticosteroid Insufficiency in Cirrhotic Patients With Acute Gastroesophageal Variceal Bleeding

2014 ◽  
Vol 42 (12) ◽  
pp. 2546-2555 ◽  
Author(s):  
Ming-Hung Tsai ◽  
Hui-Chun Huang ◽  
Yun-Shing Peng ◽  
Yung-Chang Chen ◽  
Ya-Chung Tian ◽  
...  
Keyword(s):  
Critical Illness ◽  
Variceal Bleeding ◽  
Cirrhotic Patients ◽  
Corticosteroid Insufficiency

scholarly journals Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part I)

2017 ◽  
Vol 45 (12) ◽  
pp. 2078-2088 ◽  
Author(s):  
Djillali Annane ◽  
Stephen M. Pastores ◽  
Bram Rochwerg ◽  
Wiebke Arlt ◽  
Robert A. Balk ◽  
...  
Keyword(s):  
Critical Illness ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Diagnosis And Management ◽  
Corticosteroid Insufficiency
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