Adjunctive therapy with intravenous lipid emulsion and methocarbamol for permethrin toxicity in 2 cats

2013 ◽  
Vol 23 (4) ◽  
pp. 436-441 ◽  
Author(s):  
Kendon Kuo ◽  
Adesola Odunayo
2020 ◽  
Vol 8 (2) ◽  
pp. e001041
Author(s):  
Matthew A Kopke ◽  
Ivayla D Yozova

A seven-month-old Cavalier King Charles spaniel presented with generalised, coarse muscle tremors that progressed to seizure activity, after observed ingestion (licking) of a cleaning product containing permethrin. At the time of presentation, the dog was receiving prednisone as management for masticatory muscle myositis. The dog was treated with symptomatic and supportive therapy in the form of midazolam, dexmedetomidine and intravenous lipid emulsion (ILE). This case details the first reported use of ILE as adjunctive therapy in the successful management of canine permethrin toxicosis. No further tremors or seizure activity, nor any adverse effects were observed following administration of ILE therapy.


2016 ◽  
Vol 34 (8) ◽  
pp. 1732.e3-1732.e4 ◽  
Author(s):  
James Tse ◽  
Kevin Ferguson ◽  
K. Scott Whitlow ◽  
Karly Erickson

2020 ◽  
Vol 28 (5) ◽  
pp. e612-e614
Author(s):  
Mohammed T. Awad ◽  
Mujahed Alkhathlan ◽  
Samantha L. Spetz ◽  
Michael Conley ◽  
Ragheb Assaly

2018 ◽  
Vol 6 (4) ◽  
Author(s):  
Marco Pelizzola ◽  
Clara Mattavelli ◽  
Roberta Troìa ◽  
Elsa Murgia ◽  
Massimo Giunti

2016 ◽  
Vol 34 (6) ◽  
pp. 1112-1116 ◽  
Author(s):  
Bülent Serhan Yurtlu ◽  
Şule Özbilgin ◽  
Derya Arslan Yurtlu ◽  
Nilay Boztaş ◽  
Gonca Kamacı ◽  
...  

2013 ◽  
Vol 30 ◽  
pp. 3-3
Author(s):  
J. Heinonen ◽  
E. Litonius ◽  
J. T. Backman ◽  
P. J. Neuvonen ◽  
P. H. Rosenberg

2021 ◽  
Vol 8 ◽  
Author(s):  
Amanda M. Spillane ◽  
Jenica L. Haraschak ◽  
Maureen A. McMichael

A 5-month-old male intact Great Pyrenees was presented for an acute onset of severe neurologic signs (stupor, absent menace, intermittent head turn to the left). The patient's history included possible naproxen ingestion with a maximum ingested dose of 59 mg/kg, exceeding the reported dose of >50 mg/kg known to cause neurologic signs. Blood sampling for baseline bloodwork was performed, and intravenous lipid emulsion (ILE) was subsequently administered, for treatment of the suspected toxicosis. Due to severe and life-threatening neurologic signs, other methods of decontamination were contraindicated and unlikely to be effective; extracorporeal therapy was also unavailable. Complete resolution of neurologic signs occurred 30 min after completion of ILE therapy. At this time, the owners found the missing naproxen tablets after returning home and the bloodwork results returned revealing findings consistent with hepatic encephalopathy. The fasted blood ammonia concentration immediately prior to ILE administration was 702.1 μg/dL (reference interval, RI: 24–36 μg/dL) and decreased to 194.1 μg/dL 24 h later. In the first 24 h, the patient also received three doses of lactulose, N-acetylcysteine, and intravenous fluids. The patient was subsequently diagnosed with a single, large intrahepatic portosystemic shunt via computed tomography and underwent an endovascular coil embolization procedure. Given the rapid and dramatic improvement in severe neurologic signs after ILE therapy alone, it is strongly suspected that this treatment resulted in improvement of hepatic encephalopathy.


Author(s):  
Frederick C. Cobey ◽  
Masashi Kawabori ◽  
Roman Schumann ◽  
Gregory Couper ◽  
Iwona Bonney ◽  
...  

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