The in vitro antibacterial activity of the anthelmintic drug oxyclozanide against common small animal bacterial pathogens

2019 ◽  
Author(s):  
Matthew R. Levinson ◽  
Joseph M. Blondeau ◽  
Wayne S. Rosenkrantz ◽  
Curtis B. Plowgian
Keyword(s):  
Antibacterial Activity ◽  
Bacterial Pathogens ◽  
Small Animal ◽  
Anthelmintic Drug ◽  
In Vitro Antibacterial Activity

Synthesis and in vitro antibacterial activity of novel fluoroalkyl-substituted pyrazolyl oxazolidinones

RSC Advances ◽  
2015 ◽  
Vol 5 (90) ◽  
pp. 73660-73669 ◽  
Author(s):  
Lili Yan ◽  
Jingjing Wu ◽  
Heng Chen ◽  
Shaowu Zhang ◽  
Zhi Wang ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Bacterial Pathogens ◽  
Gram Positive ◽  
Good Antibacterial Activity ◽  
In Vitro Antibacterial Activity

A series of novel fluoroalkyl-substituted pyrazole bearing oxazolidinone derivatives were synthesized and evaluated for their antibacterial activity against six Gram-positive bacterial pathogens. Most have good antibacterial activity, three being comparable to linezolid.

COMPARATIVE IN VITRO ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACT OF PLUMBAGO ZEYLENICA

INDIAN DRUGS ◽  
2013 ◽  
Vol 50 (04) ◽  
pp. 53-55
Author(s):  
G.P Vadnere ◽  
◽  
A.R. Pathan ◽  
B.U Kulkarni ◽  
A.K. Singhai
Keyword(s):  
Antibacterial Activity ◽  
Bacterial Pathogens ◽  
Bacterial Pathogen ◽  
Ethanolic Extract ◽  
Salmonella Typhi ◽  
Gastrointestinal Disorders ◽  
Moderate Activity ◽  
White Variety ◽  
In Vitro Antibacterial Activity

Ethanolic extract of leaf, flower and root of Plumbago zeylenica L. (white variety) traditionally used in the treatment of gastrointestinal disorders were screened for antibacterial activity against bacterial pathogens Staphyllococcus aureus, Escerchia coli, Klebsiella pneumoniae, Enterobacter aurugens, Proteus vulgaris, Shigella sonnei, Salmonella typhi which are known to cause different type of gastrointestinal disorders. The results showed that leaf and root extracts exhibited strong antibacterial action at concentration of 2-8 mg/ mL of the bacterial pathogen tested. However, powdered flower extract showed moderate activity. Thus the present data reveals that leaves and flowers are equally potential for the treatment of bacterial pathogens, which causes intestinal catarrh, indigestion, and colic intestinal abscesses.

In Vitro Antibacterial activity of ethanolic extract of Myrsine africana against laboratory Strains of Pathogenic Organisms

2016 ◽  
Vol 5 (04) ◽  
pp. 4512
Author(s):  
Jackie K. Obey ◽  
Anthoney Swamy T* ◽  
Lasiti Timothy ◽  
Makani Rachel
Keyword(s):  
Antibacterial Activity ◽  
Minimum Inhibitory Concentration ◽  
Inhibitory Concentration ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
E Coli ◽  
Zones Of Inhibition ◽  
In Vitro Antibacterial Activity ◽  
Myrsine Africana

The determination of the antibacterial activity (zone of inhibition) and minimum inhibitory concentration of medicinal plants a crucial step in drug development. In this study, the antibacterial activity and minimum inhibitory concentration of the ethanol extract of Myrsine africana were determined for Escherichia coli, Bacillus cereus, Staphylococcus epidermidis and Streptococcus pneumoniae. The zones of inhibition (mm±S.E) of 500mg/ml of M. africana ethanol extract were 22.00± 0.00 for E. coli,20.33 ±0.33 for B. cereus,25.00± 0.00 for S. epidermidis and 18. 17±0.17 for S. pneumoniae. The minimum inhibitory concentration(MIC) is the minimum dose required to inhibit growth a microorganism. Upon further double dilution of the 500mg/ml of M. africana extract, MIC was obtained for each organism. The MIC for E. coli, B. cereus, S. epidermidis and S. pneumoniae were 7.81mg/ml, 7.81mg/ml, 15.63mg/ml and 15.63mg/ml respectively. Crude extracts are considered active when they inhibit microorganisms with zones of inhibition of 8mm and above. Therefore, this study has shown that the ethanol extract of M. africana can control the growth of the four organisms tested.

scholarly journals Evaluation of the in vitro antibacterial activity of some essential oils and their blends against Staphylococcus spp. isolated from episodes of sheep mastitis

2021 ◽  
Author(s):  
Filippo Fratini ◽  
Margherita Giusti ◽  
Simone Mancini ◽  
Francesca Pisseri ◽  
Basma Najar ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Essential Oils ◽  
Diffusion Method ◽  
Minimal Bactericidal Concentration ◽  
Coagulase Negative Staphylococci ◽  
Disk Diffusion Method ◽  
In Vitro Antibacterial Activity ◽  
High Concentrations ◽  
Thymus Serpyllum

AbstractStaphylococcus aureus and coagulase-negative staphylococci are among the major causes of mastitis in sheep. The main goal of this research was to determine the in vitro antibacterial activity of several essential oils (EOs, n 30), then five of them were chosen and tested alone and in blends against staphylococci isolates. Five bacteria were isolated from episodes of ovine mastitis (two S. aureus and three S. xylosus). Biochemical and molecular methods were employed to identify the isolates and disk diffusion method was performed to determine their antimicrobial-resistance profile. The relative percentage of the main constituents in the tested essential oils and their blends was detected by GC-EIMS analysis. Antibacterial and bactericidal effectiveness of essential oils and blends were evaluated through minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC). All of them showed sensitivity to the used antimicrobials. The EOs with the highest antibacterial activity were those belonging to the Lamiaceae family characterized by high concentrations of thymol, carvacrol and its precursor p-cymene, together with cinnamon EO, rich in cinnamaldehyde. In terms of both MIC and MBC values, the blend composed by Thymus capitatus EO 40%, Cinnamomum zeylanicum EO 20%, Thymus serpyllum EO 20% and Satureja montana EO 20% was found to be the most effective against all the isolates. Some essential oils appear to represent, at least in vitro, a valid tool against ovine mastitis pathogens. Some blends showed a remarkable effectiveness than the single oils, highlighting a synergistic effect in relation to the phytocomplex.

In-vitro antibacterial activity of cefoperazone, a piperazine cephalosporin

1981 ◽  
Vol 8 (2) ◽  
pp. 107-113 ◽  
Author(s):  
Anna King ◽  
Christine Warren ◽  
Kevin Shannon ◽  
Ian Phillips
Keyword(s):  
Antibacterial Activity ◽  
In Vitro Antibacterial Activity
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