Determination of minimum inhibitory concentrations for silver sulfadiazine and other topical antimicrobial agents against strains of Pseudomonas aeruginosa isolated from canine otitis externa

2019 ◽  
Vol 30 (2) ◽  
pp. 145-e42 ◽  
Author(s):  
Maritta S. E. Silva‐Tarouca ◽  
Georg Wolf ◽  
Ralf S. Mueller
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Otitis Externa ◽  
Antimicrobial Agents ◽  
Silver Sulfadiazine ◽  
Minimum Inhibitory Concentrations ◽  
Topical Antimicrobial

scholarly journals Determination of N-acylhomoserine lactones of Pseudomonas aeruginosa in clinical samples from dogs with otitis externa

2016 ◽  
Vol 12 (1) ◽  
Author(s):  
Darja Kušar ◽  
Karin Šrimpf ◽  
Petra Isaković ◽  
Lina Kalšek ◽  
Javid Hosseini ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Otitis Externa ◽  
Clinical Samples

Plaquelike Clearings Induced by Antimicrobial Agents on Lawns of Pseudomonas aeruginosa

1970 ◽  
Vol 1 (2) ◽  
pp. 190-194
Author(s):  
Marian W. Wolfe ◽  
Daniel Amsterdam
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antimicrobial Susceptibility ◽  
Antimicrobial Agents ◽  
Biochemical Properties ◽  
Plaque Formation ◽  
Previous Exposure ◽  
Susceptibility Pattern ◽  
Antimicrobial Susceptibility Pattern ◽  
The Relationship

Plaques similar in appearance to those induced by phage were observed adjacent to chloramphenicol and tetracycline discs on Pseudomonas aeruginosa lawns used for the determination of antibiotic susceptibility. Thirteen strains were selected for study, 10 of which exhibited the plaquing phenomenon. The ability to form plaques induced by tetracycline was not related to any of the biochemical properties of the strains studied, their overall antimicrobial susceptibility pattern, or their pathological source. Some pseudomonad strains were capable of pyocin production; however, the relationship between plaque formation and pyocin production was not apparent. Supernatant fluids of resuspended plaque contents of eight strains originally demonstrating clearings could induce plaques on sensitive indicator lawns only when collected from tetracycline-induced plaque areas; supernatant fluids of the same strains could not produce clearings without previous exposure to the drug. Of the eight supernatant fluids capable of plaque induction, three were active on their homologous indicator lawns. In a subsequent survey of 95 P. aeruginosa strains, it was found that 28 isolates exhibited plaques. Of these, 17 were associated with tetracycline, 7 were associated with chloramphenicol, 3 were associated with triple sulfa; and 1 was associated with nalidixic acid.

Efficacy of Topical Antimicrobial Agents Against Bacterial Isolates From Burn Wounds

2020 ◽  
Vol 41 (4) ◽  
pp. 739-742
Author(s):  
William Nethery ◽  
Petra Warner ◽  
Paula Durkee ◽  
Angela Dwyer ◽  
Jacquelyn Zembrodt ◽  
...  
Keyword(s):  
Antimicrobial Agents ◽  
Polymyxin B ◽  
Silver Sulfadiazine ◽  
Bacterial Isolates ◽  
Prevention Of Infection ◽  
Burn Care ◽  
Topical Antimicrobials ◽  
Neomycin Sulfate ◽  
Topical Antimicrobial

Abstract Topically applied antimicrobials are key to the prevention of infection and mortality in the acute burn population. The purpose of this study was to determine the in vitro effectiveness of commercially available topical antimicrobials, as well as topical preparations that were compounded in our burn care institution. One-hundred twenty microorganisms were tested against these topical antimicrobials and in vitro effectiveness was observed. Results showed that compounded preparations of 1:1:1 + Double Antibiotic (1 part bacitracin: 1 part silver sulfadiazine: 100,000 units/g nystatin + 5 mg/g neomycin sulfate + 500 units/g polymyxin B) and 3:1 + Double Antibiotic (3 part bacitracin: 1 part silver sulfadiazine + 5mg/g neomycin sulfate + 500 units/g polymyxin B) were effective against 100% of the isolates tested. Other topical agents showed moderate effectiveness, thus demonstrating the need for multiple topical agents to reach a broad spectrum of microorganisms. However, the development of topical antimicrobial resistance needs further study.

scholarly journals Comparative diffusion assay to assess efficacy of topical antimicrobial agents against Pseudomonas aeruginosa in burns care

2011 ◽  
Vol 10 (1) ◽  
pp. 27 ◽  
Author(s):  
Fabien Aujoulat ◽  
Françoise Lebreton ◽  
Sara Romano ◽  
Milena Delage ◽  
Hélène Marchandin ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antimicrobial Agents ◽  
Diffusion Assay ◽  
Topical Antimicrobial
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