Reference intervals for biochemical blood variables, packed cell volume, and body temperature in pet rats (Rattus norvegicus) using point-of-care testing

2016 ◽  
Vol 45 (4) ◽  
pp. 669-679 ◽  
Author(s):  
Anneleen Houtmeyers ◽  
Luc Duchateau ◽  
Bettina Grünewald ◽  
Katleen Hermans
Keyword(s):  
Body Temperature ◽  
Cell Volume ◽  
Packed Cell Volume ◽  
Rattus Norvegicus ◽  
Point Of Care ◽  
Reference Intervals ◽  
Point Of Care Testing ◽  
Blood Variables

scholarly journals Seasonal and geographic variation in packed cell volume and selected serum chemistry of platypuses

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jana Stewart ◽  
Gilad Bino ◽  
Tahneal Hawke ◽  
Richard T. Kingsford
Keyword(s):  
Cell Volume ◽  
Geographic Variation ◽  
Packed Cell Volume ◽  
Meta Analysis ◽  
Condition Index ◽  
Blood Chemistry ◽  
Reference Intervals ◽  
Volume Index ◽  
Serum Chemistry ◽  
Eastern Australia

AbstractPlatypuses (Ornithorhynchus anatinus) inhabit the permanent rivers and creeks of eastern Australia, from north Queensland to Tasmania, but are experiencing multiple and synergistic anthropogenic threats. Baseline information of health is vital for effective monitoring of populations but is currently sparse for mainland platypuses. Focusing on seven hematology and serum chemistry metrics as indicators of health and nutrition (packed cell volume (PCV), total protein (TP), albumin, globulin, urea, creatinine, and triglycerides), we investigated their variation across the species’ range and across seasons. We analyzed 249 unique samples collected from platypuses in three river catchments in New South Wales and Victoria. Health metrics significantly varied across the populations’ range, with platypuses from the most northerly catchment, having lower PCV, and concentrations of albumin and triglycerides and higher levels of globulin, potentially reflecting geographic variation or thermal stress. The Snowy River showed significant seasonal patterns which varied between the sexes and coincided with differential reproductive stressors. Male creatinine and triglyceride levels were significantly lower than females, suggesting that reproduction is energetically more taxing on males. Age specific differences were also found, with juvenile PCV and TP levels significantly lower than adults. Additionally, the commonly used body condition index (tail volume index) was only negatively correlated with urea, and triglyceride levels. A meta-analysis of available literature revealed a significant latitudinal relationship with PCV, TP, albumin, and triglycerides but this was confounded by variation in sampling times and restraint methods. We expand understanding of mainland platypuses, providing reference intervals for PCV and six blood chemistry, while highlighting the importance of considering seasonal variation, to guide future assessments of individual and population condition.

scholarly journals In vivo antimalarial activity of the crude leaf extract of Combretum molle against Plasmodium berghei in mice

2020 ◽  
Author(s):  
Melkamu Adigo Shibeshi ◽  
Tezera Jemere Aragaw ◽  
Getnet Mequanint Adinew ◽  
Engdaw Fentahun Enyew
Keyword(s):  
Body Temperature ◽  
Survival Time ◽  
Cell Volume ◽  
Crude Extract ◽  
Plasmodium Berghei ◽  
Packed Cell Volume ◽  
Antimalarial Activity ◽  
Swiss Albino Mice ◽  
Combretum Molle

Abstract Background Malaria is an infectious, hematologic disease causing death and illness in children and adults, especially in tropical countries. The aim of this study was to evaluate the antimalarial activity of Combretum molle extract in vivo assays against Plasmodium berghei in Swiss albino mice. Methods Plasmodium berghei a rodent malaria parasite was inoculated to healthy Swiss Albino mice age 6–8 weeks either sex, weight 20–33g. 100, 200 and 400mg/kg/day of Crude methanolic extract of Combretum molle were administered. Parameters such as Percent parasitemia, body weight, Body temperature, packed cell volume and survival time were then determined using standard tests. Data were analyzed using one-way ANOVA followed by the Post hoc Tukey HSD test with SPSS software version 24.0 and P ≤0.05 considered as statistically significant. Results Chemosuppresive effect exerted by the crude extract ranged between 27-68%. The curative effect of the crude extract was in the range of 25-49% and ptophylactic effect of the crude extract was in the range of 51–76.2%%. The maximum effect in all tests on Chemosuppresive, curative, Prophylactic, prevention of weight loss, body temperature and packed cell volume and an increase in mean survival time was observed at higher doses of the crude extract. Conclusion From the present study it can be concluded that the crude extract of Combretum molle leaves has been shown promising antimalarial activity. This finding supports the traditional use of the plant for the treatment of malaria in Ethiopia. Thus, it could be considered as a potential source to develop safe, effective and affordable antimalarial agent.

scholarly journals Effects of Nigeria Ekete light crude oil on plasma electrolytes, packed cell volume (PCV) and lipids profile in wistar (Rattus norvegicus) rats

2015 ◽  
Vol 14 (24) ◽  
pp. 2047-2051 ◽  
Author(s):  
Olumide Ojo Alaba ◽  
S I Jaja ◽  
Olubayode Bamidele ◽  
Lawrence D Babatunde ◽  
Taiye F Femmymale
Keyword(s):  
Crude Oil ◽  
Cell Volume ◽  
Packed Cell Volume ◽  
Rattus Norvegicus ◽  
Light Crude Oil ◽  
Plasma Electrolytes ◽  
Lipids Profile

Packed Cell Volume Reference Intervals to Aid in the Diagnosis of Anemia and Polycythemia in Young Leghorn Chickens

1991 ◽  
Vol 35 (4) ◽  
pp. 820 ◽  
Author(s):  
Mark A. Goodwin ◽  
John Brown ◽  
Kenneth S. Latimer ◽  
Sharon L. Miller
Keyword(s):  
Cell Volume ◽  
Packed Cell Volume ◽  
Reference Intervals
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