Morphometric evaluation of the fetal rat liver after maternal dexamethasone treatment: effect on the maturation of erythroid and megakaryocytic cells

2013 ◽  
Vol 42 (4) ◽  
pp. 483-489
Author(s):  
Flávia Macedo de Oliveira Neves ◽  
Camila Cicconi Paccola ◽  
Sandra Maria Miraglia ◽  
Ivone Cipriano
Keyword(s):  
Rat Liver ◽  
Treatment Effect ◽  
Dexamethasone Treatment ◽  
Fetal Rat ◽  
Fetal Rat Liver ◽  
Morphometric Evaluation

Effects of Steroids on Fetal Rat Liver

1969 ◽  
Vol 27 ◽  
pp. 350-351
Author(s):  
F. G. Zaki
Keyword(s):  
Liver Injury ◽  
Rat Liver ◽  
Fetal Liver ◽  
Dosage Level ◽  
Maternal Plasma ◽  
Methyl Prednisolone ◽  
Fetal Rat ◽  
Toxic Agents ◽  
Fetal Rat Liver ◽  
Neonatal Liver

Fetal and neonatal liver injury induced by agents circulating in maternal plasma, even though well recognized, its morphological manifestations are not yet established. As part of our studies of fetal and neonatal liver injury induced by maternal nutritional disorders, metabolic impairment and toxic agents, the effects of two anti-inflammatory steroids have been recently inves tigated.Triamcinolone and methyl prednisolone were injected each in a group of rats during pregnancy at a-dosage level of 2 mgm three times a week. Fetal liver was studied at 18 days of gestation. Litter size and weight markedly decreased than those of control rats. Stillbirths and resorption were of higher incidence in the triamcinolone group than in those given the prednisolone.

Changes in the properties of fetal rat liver during organ culture

In Vitro ◽  
1979 ◽  
Vol 15 (8) ◽  
pp. 579-586
Author(s):  
Carl Monder ◽  
Alena Hatle Coufalik
Keyword(s):  
Organ Culture ◽  
Rat Liver ◽  
Fetal Rat ◽  
Fetal Rat Liver

Hormonal control of fructose 2,6-bisphosphate concentration and of phosphofructokinase 2 in the rat liver during development

1986 ◽  
Vol 6 (6) ◽  
pp. 513-518 ◽  
Author(s):  
Christian Schubert ◽  
Hans-Joachim Boehme ◽  
Eberhard Hofmann
Keyword(s):  
Rat Liver ◽  
Total Activity ◽  
Hormonal Control ◽  
Developmental Changes ◽  
Adrenal Hormones ◽  
Phosphorylation State ◽  
Exogenous Glucose ◽  
Substrate Supply ◽  
Fetal Rat ◽  
Fetal Rat Liver

In fetal rat liver the concentration of fructose 2,6-bisphosphate is decreased by administration of glucagon. The glucagon effect, i.e., the phosphorylation state of phosphofructokinase 2, dominates over the substrate supply. Insulin was found to increase fructose 2,6-bisphosphate only when exogenous glucose is supplied simultaneously. The total activity of phosphofructokinase 2 exhibits remarkable developmental changes. It is high at term, moderate in the fetal as well as in the mature organ, and low during suckling. The level of the enzyme during development is controlled by pancreatic and adrenal hormones.

Sign in / Sign up

Export Citation Format

Share Document