scholarly journals A randomized, controlled, behavioral intervention to promote walking after abdominal organ transplantation: results from the LIFT study

2020 ◽  
Vol 33 (6) ◽  
pp. 632-643 ◽  
Author(s):  
Marina Serper ◽  
Iwan Barankay ◽  
Sakshum Chadha ◽  
Justine Shults ◽  
Lauren S. Jones ◽  
...  
Keyword(s):  
Organ Transplantation ◽  
Behavioral Intervention ◽  
Abdominal Organ ◽  
Randomized Controlled

Clinical Outcomes in Patients Receiving Simultaneous Heart and Abdominal Organ Transplantation

2015 ◽  
Vol 34 (4) ◽  
pp. S176-S177
Author(s):  
S. Fedson ◽  
C. Murks ◽  
L. Potter ◽  
s. Qamar ◽  
T. Riley ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Organ Transplantation ◽  
Abdominal Organ

scholarly journals Randomized Controlled Pilot Study of Antiretrovirals and a Behavioral Intervention for Persons With Acute HIV Infection: Opportunity for Interrupting Transmission

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
William C Miller ◽  
Sarah E Rutstein ◽  
Sam Phiri ◽  
Gift Kamanga ◽  
Dominic Nsona ◽  
...  
Keyword(s):  
Pilot Study ◽  
Hiv Infection ◽  
Behavioral Intervention ◽  
Sexually Transmitted Infection ◽  
Health Benefit ◽  
Acute Hiv Infection ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Randomized Controlled ◽  
Acute Hiv

Abstract Background Persons with acute HIV infection (AHI) have heightened transmission risk. We evaluated potential transmission reduction using behavioral and biomedical interventions in a randomized controlled pilot study in Malawi. Methods Persons were randomized 1:2:2 to standard counseling (SC), 5-session behavioral intervention (BI), or behavioral intervention plus 12 weeks of antiretrovirals (ARVs; BIA). All were followed for 26–52 weeks and, regardless of arm, referred for treatment according to Malawi-ARV guidelines. Participants were asked to refer partners for testing. Results Among 46 persons (9 SC, 18 BI, 19 BIA), the average age was 28; 61% were male. The median viral load (VL) was 5.9 log copies/mL at enrollment. 67% (10/15) of BIA participants were suppressed (<1000 copies/mL) at week 12 vs 25% BI and 50% SC (P = .07). Although the mean number of reported condomless sexual acts in the past week decreased from baseline across all arms (1.5 vs 0.3 acts), 36% experienced incident sexually transmitted infection by 52 weeks (12% SC, 28% BI, 18% BIA). Forty-one percent (19/46) of participants referred partners (44% SC, 44% BI, 37% BIA); 15 of the partners were HIV-infected. Conclusions Diagnosis of AHI facilitates behavioral and biomedical risk reduction strategies during a high-transmission period that begins years before people are typically identified and started on ARVs. Sexually transmitted infection incidence in this cohort suggests ongoing risk behaviors, reinforcing the importance of early intervention with ARVs to reduce transmission. Early diagnosis coupled with standard AHI counseling and early ARV referral quickly suppresses viremia, may effectively change behavior, and could have tremendous public health benefit in reducing onward transmission.

scholarly journals The Behavioral Wellness in Pregnancy study: a randomized controlled trial of a multi-component intervention to promote appropriate weight gain

2019 ◽  
Vol 109 (4) ◽  
pp. 1071-1079
Author(s):  
Lyndi M Buckingham-Schutt ◽  
Laura D Ellingson ◽  
Spyridoula Vazou ◽  
Christina G Campbell
Keyword(s):  
Weight Gain ◽  
Gestational Weight Gain ◽  
Behavioral Intervention ◽  
Controlled Trial ◽  
Institute Of Medicine ◽  
Weight Retention ◽  
Gestational Weight ◽  
Randomized Controlled ◽  
Prepregnancy Weight ◽  
The Face

ABSTRACT Background Adequate weight gain during pregnancy is important to both maternal and fetal outcomes. To date, randomized controlled trials have not been effective at increasing the proportion of women meeting gestational weight-gain guidelines. Objectives The aim of this study was to determine whether a multi-component behavioral intervention with a Registered Dietitian Nutritionist significantly improves the proportion of women who adhere to the 2009 Institute of Medicine weight-gain guidelines. Methods Participants were randomly assigned to usual care (UC; n = 24) or intervention (n = 23) between 8 and 14 weeks of gestation. The intervention included a minimum of 6 one-on-one counseling sessions over ∼30 wk focusing on healthy diet and physical activity (PA) goals. In addition to the face-to-face visits, weekly communication via email supported healthy eating, PA, and appropriate weight gain. Gestational weight gain, PA, and diet were assessed at 8–14, 26–28, and 34–36 weeks of gestation; weight retention was measured 2 mo postpartum. Results The proportion of women meeting the guidelines was significantly greater in those receiving the intervention than UC (60.8% compared with 25.0%, OR: 4.7; 95% CI: 1.3, 16.2; P = 0.019). Furthermore, 36.4% of the intervention women were at or below their prepregnancy weight at 2 mo postpartum compared with 12.5% in the UC group (P = 0.05). Conclusions A multi-component behavioral intervention improved adherence to the 2009 Institute of Medicine weight-gain guidelines. This trial was registered with clinicaltrials.gov as NCT02168647.

Abdominal Organ Transplantation: An Overview

2015 ◽  
pp. 489-510
Author(s):  
Jan P. M. Lerut ◽  
Laurent Coubeau ◽  
Robert J. Stratta ◽  
Giuseppe Orlando
Keyword(s):  
Organ Transplantation ◽  
Abdominal Organ
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