scholarly journals Bariatric surgery prior to living donor nephrectomy: a solution to expand the living donor kidney pool – a retrospective study

2019 ◽  
Vol 32 (7) ◽  
pp. 702-709 ◽  
Author(s):  
Minh‐Tri J. P. Nguyen ◽  
Dustin Carpenter ◽  
Joseph Tadros ◽  
Abhishek Mathur ◽  
Pedro Rodrigo Sandoval ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Retrospective Study ◽  
Living Donor ◽  
Donor Nephrectomy ◽  
Donor Kidney ◽  
Living Donor Nephrectomy ◽  
Living Donor Kidney

scholarly journals Lower rate of delayed graft function is observed when epidural analgesia for living donor nephrectomy is administered.

2019 ◽  
Author(s):  
Wolfgang Baar ◽  
Ulrich Goebel ◽  
Hartmut Buerkle ◽  
Bernd Jaenigen ◽  
Kai Kaufmann ◽  
...  
Keyword(s):  
Epidural Analgesia ◽  
Living Donor ◽  
Graft Function ◽  
Donor Nephrectomy ◽  
Delayed Graft Function ◽  
Donor Kidney ◽  
Kidney Donors ◽  
Living Donor Nephrectomy ◽  
Kidney Transplantations ◽  
Living Donor Kidney

Abstract Background The beneficial effects of epidural analgesia (EDA) in terms of pain control and postoperative convalescence are widely known and led to a frequent use for patients who underwent living donor kidney nephrectomy. The objective of this study was to determine whether general anesthesia (GA) plus EDA compared to GA only, administered for living donor nephrectomy has effects on postoperative graft function in recipients. Methods In this monocentric, retrospective cohort analysis we analyzed the closed files of all consecutive donor- recipient pairs who underwent living donor kidney transplantations from 2008 to 2017. The outcome variable was delayed graft function (DGF), defined as at least one hemodialysis within seven days postoperatively, once hyperacute rejection, vascular or urinary tract complications were ruled out. Statistical analyses of continuous variables were calculated using the two-tail Student’s t test and Fisher exact test for categorical variables with a significance level of p<0.05, respectively. Results The study enclosed 291 consecutive living donor kidney transplantations. 99 kidney donors received epidural analgesia whereas 192 had no epidural analgesia. The groups showed balanced pretransplantational characteristics and comparable donors´ and recipients’ risk factors. 9 out of all 291 recipients needed renal replacement therapy (RRT) during the first 7 days due to delayed graft function; none of these donors received EDA. The observed rate of DGF in recipients whose kidney donors received epidural analgesia was significantly lower (0% vs. 4.6%; p=0.031). Conclusions In our cohort we observed a significantly lower rate of DGF when epidural analgesia for donor nephrectomy was administered. Due to restrictions of the study design this observation needs further confirmation by prospective studies.

scholarly journals Epidural analgesia for living donor nephrectomy is associated with better early graft function in recipients after transplantation

2018 ◽  
Author(s):  
Wolfgang Baar ◽  
Ulrich Goebel ◽  
Hartmut Buerkle ◽  
Bernd Jaenigen ◽  
Kai Kaufmann ◽  
...  
Keyword(s):  
Epidural Analgesia ◽  
Living Donor ◽  
Graft Function ◽  
Donor Nephrectomy ◽  
Delayed Graft Function ◽  
Donor Kidney ◽  
Kidney Donors ◽  
Living Donor Nephrectomy ◽  
Kidney Transplantations ◽  
Living Donor Kidney

Abstract Background: The beneficial effects of epidural analgesia (EDA) in terms of pain control and postoperative convalescence are widely known and led to a frequent use for patients who underwent living donor kidney nephrectomy. The objective of this study was to determine whether general anesthesia (GA) plus EDA compared to GA only, administered for living donor nephrectomy has effects on postoperative graft function in recipients. Methods: In this monocentric, retrospective cohort analysis we analyzed the closed files of all consecutive donor- recipient pairs who underwent living donor kidney transplantations from 2008 to 2017. The outcome variable was delayed graft function (DGF), defined as at least one hemodialysis within seven days postoperatively, once hyperacute rejection, vascular or urinary tract complications were ruled out. Statistical analyses of continuous variables were calculated using the two-tail Student’s t test and Fisher exact test for categorical variables with a significance level of p<0.05, respectively. Results: The study enclosed 291 consecutive living donor kidney transplantations. 99 kidney donors received epidural analgesia whereas 192 denied epidural analgesia. The groups showed balanced pretransplantational characteristics and comparable donors´ and recipients’ risk factors. 9 out of all 291 recipients needed renal replacement therapy (RRT) during the first 7 days due to delayed graft function; all of these donors received no EDA. The observed rate of DGF in recipients whose kidney donors received epidural analgesia was significantly lower (0% vs. 4.6%; p<0.031). Conclusions: In our cohort we observed a significantly lower rate of DGF when epidural analgesia for donor nephrectomy was administered. Du to restrictions of the study design this observation needs further confirmation by prospective studies. Key words: Kidney transplantation, delayed graft function, epidural analgesia, donor nephrectomy

scholarly journals Lower rate of delayed graft function is observed when epidural analgesia for living donor nephrectomy is administered

2019 ◽  
Author(s):  
Wolfgang Baar ◽  
Ulrich Goebel ◽  
Hartmut Buerkle ◽  
Bernd Jaenigen ◽  
Kai Kaufmann ◽  
...  
Keyword(s):  
Epidural Analgesia ◽  
Living Donor ◽  
Graft Function ◽  
Donor Nephrectomy ◽  
Delayed Graft Function ◽  
Donor Kidney ◽  
Kidney Donors ◽  
Living Donor Nephrectomy ◽  
Kidney Transplantations ◽  
Living Donor Kidney

Abstract Background The beneficial effects of epidural analgesia (EDA) in terms of pain control and postoperative convalescence are widely known and led to a frequent use for patients who underwent living donor kidney nephrectomy. The objective of this study was to determine whether general anesthesia (GA) plus EDA compared to GA only, administered for living donor nephrectomy has effects on postoperative graft function in recipients. Methods In this monocentric, retrospective cohort analysis we analyzed the closed files of all consecutive donor- recipient pairs who underwent living donor kidney transplantations from 2008 to 2017. The outcome variable was delayed graft function (DGF), defined as at least one hemodialysis within seven days postoperatively, once hyperacute rejection, vascular or urinary tract complications were ruled out. Statistical analyses of continuous variables were calculated using the two-tail Student’s t test and Fisher exact test for categorical variables with a significance level of p<0.05, respectively. Results The study enclosed 291 consecutive living donor kidney transplantations. 99 kidney donors received epidural analgesia whereas 192 had no epidural analgesia. The groups showed balanced pretransplantational characteristics and comparable donors´ and recipients’ risk factors. 9 out of all 291 recipients needed renal replacement therapy (RRT) during the first 7 days due to delayed graft function; none of these donors received EDA. The observed rate of DGF in recipients whose kidney donors received epidural analgesia was significantly lower (0% vs. 4.6%; p=0.031). Conclusions In our cohort we observed a significantly lower rate of DGF when epidural analgesia for donor nephrectomy was administered. Due to restrictions of the study design this observation needs further confirmation by prospective studies.

Long-term outcomes of living donor kidney transplants in pediatric recipients following laparoscopic vs. open donor nephrectomy

2012 ◽  
Vol 16 (8) ◽  
pp. 894-900 ◽  
Author(s):  
Lyubov Chaykovska ◽  
Serdar Deger ◽  
Jan Roigas ◽  
Andre Lenz ◽  
Poline Lioudmer ◽  
...  
Keyword(s):  
Living Donor ◽  
Donor Nephrectomy ◽  
Kidney Transplants ◽  
Long Term Outcomes ◽  
Donor Kidney ◽  
Pediatric Recipients ◽  
Living Donor Kidney
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