scholarly journals Occurrence of newly discovered human polyomaviruses in skin of liver transplant recipients and their relation with squamous cell carcinoma in situ and actinic keratosis – a single‐center cohort study

2019 ◽  
Vol 32 (5) ◽  
pp. 516-522 ◽  
Author(s):  
Yilin Wang ◽  
Anne Keinonen ◽  
Sari Koskenmies ◽  
Sari Pitkänen ◽  
Nanna Fyhrquist ◽  
...  
2021 ◽  
Vol 12 (2) ◽  
pp. 147-154
Author(s):  
Eden Sharabi ◽  
Allison Carroll ◽  
Peter Cummings ◽  
Josh Levitsky

Immunosuppression withdrawal (ISW) is considered in liver transplant recipients (LTRs) and autoimmune hepatitis patients (AIHPs). Immunosuppressive therapy (IST) can be burdensome both financially and due to its side effect profile, making ISW an important intervention to consider. Data on patient interest in ISW would be helpful to providers in ISW decision-making. We conducted independent single-center surveys of LTR and AIHP attitudes on IST and withdrawal interest. Of 325 LTRs screened, 120 completed the survey (50% female, mean age 58 ± 14 years, mean time since transplant 8 ± 10.5 years and 79.5% Caucasian). Of 100 AIHPs screened, 45 completed the survey (77.8% female, mean age 54 ± 2 and 82.2% Caucasian). A higher percentage of AIHPs expressed concern with their IST and were interested in ISW compared with LTRs. However, over a third of LTRs were interested in ISW, particularly those with knowledge of this potential intervention. LTRs who discussed ISW with a physician were more likely to desire withdrawal (p = 0.02; OR = 2.781 (95% CI = 1.125, 6.872)). As patient interest in ISW is of growing interest, investigators should continue to assess patient-reported desires and outcomes and pursue strategies to achieve immunological tolerance.


2021 ◽  
Author(s):  
Jacob Guorgui ◽  
Takahiro Ito ◽  
Daniela Markovic ◽  
Antony Aziz ◽  
Stephanie Younan ◽  
...  

2010 ◽  
Vol 42 (7) ◽  
pp. 2579-2584 ◽  
Author(s):  
M. Vivarelli ◽  
A. Dazzi ◽  
A. Cucchetti ◽  
A. Gasbarrini ◽  
M. Zanello ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document