scholarly journals Long-term patient survival and kidney allograft survival in post-transplant diabetes mellitus: a single-center retrospective study

2016 ◽  
Vol 29 (9) ◽  
pp. 1017-1028 ◽  
Author(s):  
Thomas Dienemann ◽  
Naohiko Fujii ◽  
Yimei Li ◽  
Shivali Govani ◽  
Nikitha Kosaraju ◽  
...  
2009 ◽  
Vol 70 ◽  
pp. S52
Author(s):  
Patricia Grenzi ◽  
Erika F. Campos ◽  
Helio Tedesco-Silva ◽  
Marcello Franco ◽  
Jose O. Medina-Pestana ◽  
...  

Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 413
Author(s):  
Theerawut Klangjareonchai ◽  
Natsuki Eguchi ◽  
Ekamol Tantisattamo ◽  
Antoney J. Ferrey ◽  
Uttam Reddy ◽  
...  

Hyperglycemia after kidney transplantation is common in both diabetic and non-diabetic patients. Both pretransplant and post-transplant diabetes mellitus are associated with increased kidney allograft failure and mortality. Glucose management may be challenging for kidney transplant recipients. The pathophysiology and pattern of hyperglycemia in patients following kidney transplantation is different from those with type 2 diabetes mellitus. In patients with pre-existing and post-transplant diabetes mellitus, there is limited data on the management of hyperglycemia after kidney transplantation. The following article discusses the nomenclature and diagnosis of pre- and post-transplant diabetes mellitus, the impact of transplant-related hyperglycemia on patient and kidney allograft outcomes, risk factors and potential pathogenic mechanisms of hyperglycemia after kidney transplantation, glucose management before and after transplantation, and modalities for prevention of post-transplant diabetes mellitus.


2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Yuan-Feng Liang ◽  
Feier Song ◽  
Huixia Liu ◽  
Jian Liu ◽  
Yu-Yuan Zhang ◽  
...  

Background. Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease (VHD) patients is unclear. This study aimed to investigate the effect of DM on the long-term outcome of elderly VHD patients. Methods. This single-center, observational study enrolled patients aged 65 and older consecutively with confirmed VHD using echocardiography. Patients, divided into the DM group and non-DM group, were followed up for major adverse cardiac and cerebrovascular events (MACCEs), including all-cause death, ischemic stroke, and heart failure rehospitalization. Results. Our study consisted of 532 patients over a median follow-up of 52.9 months. Compared with the non-DM group (n = 377), the DM group (n = 155) had higher incidences of ischemic stroke (25.2% vs. 13.5%, P = 0.001 ), heart failure rehospitalization (37.4% vs. 20.7%, P < 0.001 ), and MACCEs (60.0% vs. 35.8%, P < 0.001 ). After adjustment of confounders by the multivariable cox regression, DM appeared as an independent predictor for MACCEs (adjusted hazard ratio, aHR: 1.88; 95% confidence interval 1.42–2.48; P < 0.001 ). In the subgroup analysis of VHD etiology and functional style, conversely, DM was a protective factor for MACCEs in the patients with rheumatic VHD compared with those without rheumatic VHD (aHR: 0.43 vs. 2.27, P = 0.004 ). Conclusions. DM was an independent predictor for ischemic stroke and heart failure rehospitalization in elderly VHD patients undergoing conservative treatment.


PLoS ONE ◽  
2020 ◽  
Vol 15 (7) ◽  
pp. e0235680
Author(s):  
Anne-Sophie Mehdorn ◽  
Stefan Reuter ◽  
Barbara Suwelack ◽  
Katharina Schütte-Nütgen ◽  
Felix Becker ◽  
...  

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