Renal insufficiency, mortality, and drug management in heart transplant. Results of the CARIN study

2014 ◽  
Vol 27 (9) ◽  
pp. 931-938 ◽  
Author(s):  
Nicolas Janus ◽  
Vincent Launay-Vacher ◽  
Laurent Sebbag ◽  
Philippe Despins ◽  
Eric Epailly ◽  
...  
Keyword(s):  
Renal Insufficiency ◽  
Heart Transplant ◽  
Drug Management

Even Mild Renal Insufficiency Is a Risk for Mortality after Heart Transplant

2013 ◽  
Vol 32 (4) ◽  
pp. S40
Author(s):  
M. Kittleson ◽  
J. Patel ◽  
M. Rafiei ◽  
A. Osborne ◽  
G. Jamero ◽  
...  
Keyword(s):  
Renal Insufficiency ◽  
Heart Transplant ◽  
Mild Renal Insufficiency

scholarly journals NSS for an RCC in a patient with renal insufficiency after heart transplant because of right ventricular tumor

2013 ◽  
Vol 65 ◽  
pp. 36-38
Author(s):  
Grzegorz Prokopowicz ◽  
Marcin Życzkowski ◽  
Krzysztof Nowakowski ◽  
Piotr Bryniarski ◽  
Andrzej Paradysz
Keyword(s):  
Renal Insufficiency ◽  
Right Ventricular ◽  
Heart Transplant

Survival of Heart Transplant Recipients With Cyclosporine-Induced Renal Insufficiency

1998 ◽  
Vol 30 (4) ◽  
pp. 1122-1123 ◽  
Author(s):  
T. van Gelder ◽  
A.H.M.M. Balk ◽  
R. Zietse ◽  
C. Hesse ◽  
B. Mochtar ◽  
...  
Keyword(s):  
Renal Insufficiency ◽  
Heart Transplant ◽  
Transplant Recipients ◽  
Heart Transplant Recipients

Outcome of heart transplant in patients with renal insufficiency

2001 ◽  
Vol 20 (2) ◽  
pp. 248 ◽  
Author(s):  
F.L. Adajar ◽  
C.E. Lawless ◽  
K. Malinowska
Keyword(s):  
Renal Insufficiency ◽  
Heart Transplant

Drug Management of Prostate Cancer: Prevalence and Consequences of Renal Insufficiency

2009 ◽  
Vol 7 (3) ◽  
pp. E83-E89 ◽  
Author(s):  
Vincent Launay-Vacher ◽  
Jorge Ayllon ◽  
Nicolas Janus ◽  
Jean-Philippe Spano ◽  
Isabelle Ray-Coquard ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Renal Insufficiency ◽  
Drug Management ◽  
Cancer Prevalence

scholarly journals The CECARI Study: Everolimus (Certican®) Initiation and Calcineurin Inhibitor Withdrawal in Maintenance Heart Transplant Recipients with Renal Insufficiency: A Multicenter, Randomized Trial

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Jan Van Keer ◽  
David Derthoo ◽  
Olivier Van Caenegem ◽  
Michel De Pauw ◽  
Eric Nellessen ◽  
...  
Keyword(s):  
Adverse Events ◽  
Renal Insufficiency ◽  
Heart Transplant ◽  
Statistical Significance ◽  
Group Versus ◽  
Study Drug ◽  
Major Adverse Cardiovascular Events ◽  
Transplant Recipients ◽  
Open Label ◽  
Heart Transplant Recipients

In this 3-year, open-label, multicenter study, 57 maintenance heart transplant recipients (>1 year after transplant) with renal insufficiency (eGFR 30–60 mL/min/1.73 m2) were randomized to start everolimus with CNI withdrawal (N=29) or continue their current CNI-based immunosuppression (N=28). The primary endpoint, change in measured glomerular filtration rate (mGFR) from baseline to year 3, did not differ significantly between both groups (+7.0 mL/min in the everolimus group versus +1.9 mL/min in the CNI group, p=0.18). In the on-treatment analysis, the difference did reach statistical significance (+9.4 mL/min in the everolimus group versus +1.9 mL/min in the CNI group, p=0.047). The composite safety endpoint of all-cause mortality, major adverse cardiovascular events, or treated acute rejection was not different between groups. Nonfatal adverse events occurred in 96.6% of patients in the everolimus group and 57.1% in the CNI group (p<0.001). Ten patients (34.5%) in the everolimus group discontinued the study drug during follow-up due to adverse events. The poor adherence to the everolimus therapy might have masked a potential benefit of CNI withdrawal on renal function.

scholarly journals Prevalence of Renal Insufficiency in cancer patients and implications for anticancer drug management

Cancer ◽  
2007 ◽  
Vol 110 (6) ◽  
pp. 1376-1384 ◽  
Author(s):  
Vincent Launay-Vacher ◽  
Stéphane Oudard ◽  
Nicolas Janus ◽  
Joseph Gligorov ◽  
Xavier Pourrat ◽  
...  
Keyword(s):  
Renal Insufficiency ◽  
Cancer Patients ◽  
Anticancer Drug ◽  
Drug Management
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