An analysis of transplant glomerulopathy and thrombotic microangiopathy in kidney transplant biopsies

2014 ◽  
Vol 27 (8) ◽  
pp. 784-792 ◽  
Author(s):  
Sreejesh Sreedharanunni ◽  
Kusum Joshi ◽  
Rajan Duggal ◽  
Ritambhra Nada ◽  
Mukut Minz ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Thrombotic Microangiopathy ◽  
Transplant Glomerulopathy

Successful conversion to belatacept after thrombotic microangiopathy in kidney transplant patients

2013 ◽  
Vol 27 (4) ◽  
pp. 591-597 ◽  
Author(s):  
Sireesha Koppula ◽  
Sarah E. Yost ◽  
Amy Sussman ◽  
Erika R. Bracamonte ◽  
Bruce Kaplan
Keyword(s):  
Kidney Transplant ◽  
Thrombotic Microangiopathy ◽  
Transplant Patients ◽  
Kidney Transplant Patients

scholarly journals Use of Eculizumab in Transplant-Associated Thrombotic Microangiopathy in a Patient With Polycystic Kidney Disease Immediately Post–Kidney Transplant: A Case Report

2020 ◽  
Vol 2 (5) ◽  
pp. 652-656 ◽  
Author(s):  
Amandeep Godara ◽  
Daniel R. Migliozzi ◽  
Monika Pilichowska ◽  
Nitender Goyal ◽  
Cindy Varga ◽  
...  
Keyword(s):  
Case Report ◽  
Kidney Disease ◽  
Kidney Transplant ◽  
Polycystic Kidney Disease ◽  
Thrombotic Microangiopathy ◽  
Polycystic Kidney

scholarly journals Validation of Prognostic Index for Allograft Outcome in Kidney Transplant Recipients With Transplant Glomerulopathy

2020 ◽  
Vol 5 (6) ◽  
pp. 915-920
Author(s):  
Manish Talwar ◽  
Vasanthi Balaraman ◽  
Anshul Bhalla ◽  
Orsolya Cseprekal ◽  
Masahiko Yazawa ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Prognostic Index ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Allograft Outcome ◽  
Transplant Glomerulopathy

scholarly journals Immune Complex Mediated Glomerulonephritis with Acute Thrombotic Microangiopathy following Newly Detected Hepatitis B Virus Infection in a Kidney Transplant Recipient

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Tracey Salter ◽  
Hannah Burton ◽  
Sam Douthwaite ◽  
William Newsholme ◽  
Catherine Horsfield ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Kidney Transplant ◽  
Immune Complex ◽  
Thrombotic Microangiopathy ◽  
Hbv Infection ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Vaccine Escape Mutant ◽  
B Virus

Hepatitis B virus (HBV) presents a risk to patients and staff in renal units. To minimise viral transmission, there are international and UK guidelines recommending HBV immunisation for patients commencing renal replacement therapy (RRT) and HBV surveillance in kidney transplant recipients. We report the case of a 56-year-old male who was immunised against HBV before starting haemodialysis. He received a deceased donor kidney transplant three years later, at which time there was no evidence of HBV infection. After a further six years he developed an acute kidney injury; allograft biopsy revealed an acute thrombotic microangiopathy (TMA) with glomerulitis, peritubular capillaritis, and C4d staining. Due to a “full house” immunoprofile, tests including virological screening were undertaken, which revealed acute HBV infection. Entecavir treatment resulted in an improvement in viral load and kidney function. HBV genotyping demonstrated a vaccine escape mutant, suggesting “past resolved” infection that reactivated with immunosuppression, though posttransplant acquisition cannot be excluded. This is the first reported case of acute HBV infection associated with immune complex mediated glomerulonephritis and TMA. Furthermore, it highlights the importance of HBV surveillance in kidney transplant recipients, which although addressed by UK guidelines is not currently practiced in all UK units.

scholarly journals BK virus-related thrombotic microangiopathy in a kidney transplant recipient

2015 ◽  
Vol 9 (4) ◽  
pp. 155-158
Author(s):  
Cengiz Bulut ◽  
Ebru Gok Oguz ◽  
Basol Canbakan ◽  
Deniz Ayli
Keyword(s):  
Transplant Recipient ◽  
Kidney Transplant ◽  
Thrombotic Microangiopathy ◽  
Kidney Transplant Recipient ◽  
Bk Virus
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