Reduced risk of vasovagal reactions in Australian whole blood donors after national implementation of applied muscle tension and water loading

Transfusion ◽  
2020 ◽  
Vol 60 (5) ◽  
pp. 918-921
Author(s):  
Amanda Thijsen ◽  
Barbara Masser ◽  
Tanya E. Davison
2019 ◽  
Vol 15 (2) ◽  
pp. 253-260
Author(s):  
Karan Kumar ◽  
Suchet Sachdev ◽  
Neelam Marwaha ◽  
Ratti Ram Sharma

2013 ◽  
Vol 3 (6) ◽  
pp. 459-463 ◽  
Author(s):  
S Mangwana

Background: Hemovigilance like quality systems and audits have become an integral part of Blood Transfusion Services in the developed countries and has contributed greatly to its development. Hemovigilance begins with donors and must enable the collection of information on reactions occurring during the donation of blood, selections of donors and to prevent such incidents. The aim of study was to help identify the trends of adverse events , occurring in blood donors at a tertiary-care hospital, to recommend best practices to improve donor care and safety Materials and Methods: This record-based study was conducted on all adverse events related to allogenic whole blood donations performed over 24 months. All whole blood donations were analyzed. All adverse events occurring during or at the end of the donation were noted using a standardized format and analyzed determining significance at p<0.05. Results: Overall rate was 0.3% with vasovagal reactions constituting 82%, and 18% mild syncopal reactions (p<0.001). Immediate vasovagal reaction with injury was very rare (0.007%). Vasovagal reactions showed a significant association with young age, female gender, first time donation status. Mean age of persons recording adverse effects was 30.23 ± 7.49 years as compared to those without adverse effects, 31.14 ± 8.56 years. Conclusion: Donor safety is an essential perquisite to increase voluntary blood donation. AE analysis helps in identifying the blood donors at risk of AE, applying appropriate motivational strategies, predonation counseling, care during and after donation, developing guidelines and hemovigilance programme in countries with limited resources. DOI: http://dx.doi.org/10.3126/jpn.v3i6.8993   Journal of Pathology of Nepal (2013) Vol. 3, 459-463


Transfusion ◽  
2011 ◽  
Vol 52 (5) ◽  
pp. 1070-1078 ◽  
Author(s):  
Thelma T. Gonçalez ◽  
Ester C. Sabino ◽  
Karen S. Schlumpf ◽  
David J. Wright ◽  
Silvana Leao ◽  
...  

Transfusion ◽  
2015 ◽  
Vol 56 (1) ◽  
pp. 179-185 ◽  
Author(s):  
Christopher R. France ◽  
Janis L. France ◽  
Terri A. Frame-Brown ◽  
Geri A. Venable ◽  
Jay E. Menitove

Transfusion ◽  
2018 ◽  
Vol 59 (2) ◽  
pp. 555-565 ◽  
Author(s):  
Johanna Wiersum‐Osselton ◽  
Bas Romeijn ◽  
Elise Brekel ◽  
Anne Dongen ◽  
Frank Hermans ◽  
...  

Transfusion ◽  
2011 ◽  
Vol 51 (8) ◽  
pp. 1802-1808 ◽  
Author(s):  
Jennifer M. Kowalsky ◽  
Janis L. France ◽  
Mary Ellen Wissel ◽  
Christopher R. France

2020 ◽  
Vol 22 (1-2) ◽  
pp. 54-61
Author(s):  
Mrigendra Amatya

Adverse effects (AE) like vasovagal reactions (presyncope and syncope) have negative impact on old as well as new blood donors. Various methods have been suggested to prevent or attenuate AE in blood donors. This study assessed the effectiveness of prehydration with different fluids or applied muscle tension (AMT) during blood donation in preventing or attenuating AE. Consenting and eligible voluntary blood donors (n=448) were randomly allocated to Control (n=115), prehydration with 500 mL plain water (PW, n=97), prehydration with oral rehydration solution (ORS, n=71), prehydration with 400 mL fruit juice (FJ, n=74), or leg muscle tensing during blood removal (AMT, n=91) groups. Donors’ hemodynamic responses to blood donation were assessed by comparing blood pressures (systolic–SBP and diastolic–DBP) and heart rate (HR) recorded before blood removal to values midway during, and at 0 min, 5 min, 10 min and 15 min after blood removal. Presyncope and syncope were defined by BP and HR changes. Subjective AE were also recorded. Overall, 35 donors (7.8%) suffered AE with highest rates in PW (13.4%) and ORS (11.3%) groups and lowest in Control (3.5%) although group differences were not significant (p>0.05, Chi square). Blood removal was associated with significant falls in SBP and DBP (mean falls by 6.63 and 3.35 mmHg, respectively; p<0.001) but an insignificant rise in HR (mean increase by 0.67 bpm, p>0.05). Hemodynamic responses showed significant differences between groups (p<0.001, repeated measures ANOVA). Therefore, role of the interventions in relation to AE in blood donors could not be established.


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