Reexamination of the chromium‐51–labeled posttransfusion red blood cell recovery method

Transfusion ◽  
2019 ◽  
Vol 59 (7) ◽  
pp. 2264-2275 ◽  
Author(s):  
Richard O. Francis ◽  
Sonia Mahajan ◽  
Francesca Rapido ◽  
Francesca La Carpia ◽  
Mark Soffing ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Recovery ◽  
Recovery Method

Biochemical stabilization enhances red blood cell recovery and stability following cryopreservation

Cryobiology ◽  
2002 ◽  
Vol 45 (2) ◽  
pp. 153-166 ◽  
Author(s):  
Christopher T Wagner ◽  
Melissa L Martowicz ◽  
Stephen A Livesey ◽  
Jerome Connor
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Recovery

The Mobilization Effects of G-CSF, GM-CSF and Darbepoetin-α for Allogeneic Peripheral Blood Stem Cell Transplantation.

Blood ◽  
2007 ◽  
Vol 110 (11) ◽  
pp. 4932-4932
Author(s):  
Shi Nae Kim ◽  
Sang Kyun Sohn ◽  
Jong Gwang Kim ◽  
Yee Soo Kim ◽  
Yoon Young Cho ◽  
...  
Keyword(s):  
Stem Cells ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Red Blood Cell Transfusion ◽  
Combination Group ◽  
Combination Regimen ◽  
Cell Recovery ◽  
Hematopoietic Stem ◽  
Gm Csf ◽  
Cell Counts

Abstract Background: Granulocyte colony-stimulating-factor (G-CSF) is widely used for the mobilization of hematopoietic stem cells from normal donors. It has been reported that the addition of granulocyte-macrophage CSF (GM-CSF) to G-CSF mobilized more primitive CD34+ subsets than did G-CSF alone. We investigated the effects of combination regimen (GM-CSF + G-CSF + darbepoetin-α) for mobilization in normal healthy donors and compared its efficacy in mobilizing stem cells with G-CSF alone. Methods: Thirty donors were randomly assigned to one of the following regimens for mobilization: G-CSF group (G-CSF 5ug/kg/day for 5 to 7 days) and combination group (GM-CSF 10ug/kg/day on 1st and 2nd days, G-CSF 5ug/kg/day for 5 to 7 days and 40mg of dalbepoetin-α on day 1) Results: The counts of MNC and CD34+ cells/kg were not significantly different between two groups (p=0.129 and p=0.651). The CD3+ cell counts per kilogram were 3.48±1.45×108/kg and 2.54±0.94×108/kg in a G-CSF group and a combination group, respectively (p=0.04). Red blood cell transfusion requirement was not different between two groups (p=0.469). The median time to neutrophil and platelet engraftment was 12.5 vs. 12.0 days (p=0.443) and 11.5 vs. 11.0 days (p=0.752). Red blood cell recovery was 7.5 days and 7 days in G-CSF group and combination group, respectively (p=0.231). Grade II–IV acute graft-versus-host disease (GVHD) was observed in 20% in G-CSF group and 13% in combination group (p=0.50). Conclusion: The combination regimen was not superior to G-CSF alone in terms of acute GVHD and CD34+ cell dose. But CD3+ cell count was significantly lower in combination regimen group. The role of lower CD3+ cells in the graft need to be elucidated in the future.

scholarly journals Analysis of Cell Saver use and mortality in liver transplant

2017 ◽  
Vol 20 (3) ◽  
pp. 11-13
Author(s):  
André Ibrahim David ◽  
Catiana Mitica Gritti ◽  
André Gustavo Santos Pereira ◽  
Tiago Emanuel de Souza ◽  
Felipe Sbrolini Borges ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Similar Amount ◽  
Blood Transfusions ◽  
Cell Saver ◽  
Cell Recovery ◽  
Liver Transplants ◽  
Perioperative Mortality ◽  
Transplant Patients ◽  
Multiple Blood

Introduction: Liver transplantation is considered the best treatment for irreversible liver disease. Due to the complexity of the procedure generally multiple blood transfusions are required. One option to reduce this need is the use of Cell Saver providing blood cell recovery and reinfusion. Purpose: to evaluate mortality in the number of washed red blood cell units recovered by Cell Saver and perioperative mortality. Methods: Data collection of transplant patients using CellSaver on the period from July 2014 to February 2017. Results: Performed 56 liver transplants, the diagnosis prevalent was liver cirrhosis by hepatitis C virus (37,5%). Of these 45 (80,4%) of the transplants used Cell Saver, which had a median MELD of 24,5 (range 7-50). Taking into account the use of Cell Saver in washed red blood cell units and recovered notes a median of four (range 1-45). 12 died (26,7%), the average of these MELD was 25,5 (range 1-50) and the use of washed red blood cell and recovered was a median of 4,5. Conclusion: Patients who died used a similar amount of washed and recovered erythrocyte units.

scholarly journals In premature infants there is no decrease in 24-hour posttransfusion allogeneic red blood cell recovery after 42 days of storage

Transfusion ◽  
2017 ◽  
Vol 58 (2) ◽  
pp. 352-358 ◽  
Author(s):  
Demet Nalbant ◽  
José A. Cancelas ◽  
Donald M. Mock ◽  
Svetlana V. Kyosseva ◽  
Robert L. Schmidt ◽  
...  
Keyword(s):  
Blood Cell ◽  
Premature Infants ◽  
Red Blood Cell ◽  
Cell Recovery

Red Blood Cell Recovery and Reinfusion

2005 ◽  
Vol 23 (2) ◽  
pp. 283-294 ◽  
Author(s):  
Jonathan H. Waters
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Recovery

Processing of Human Cord Blood by Three Different Procedures for Red Blood Cell Depletion and Mononuclear Cell Recovery

Vox Sanguinis ◽  
1999 ◽  
Vol 76 (4) ◽  
pp. 237-240 ◽  
Author(s):  
Paolo Perutelli ◽  
Silvia Catellani ◽  
Lucia Scarso ◽  
Paolo Cornaglia-Ferraris ◽  
Giorgio Dini
Keyword(s):  
Blood Cell ◽  
Cord Blood ◽  
Mononuclear Cell ◽  
Red Blood Cell ◽  
Cell Depletion ◽  
Cell Recovery ◽  
Human Cord Blood

Retrospective analysis of community hospital red blood cell recovery procedures: improved utilization needed for effectiveness

Transfusion ◽  
2015 ◽  
Vol 55 (8) ◽  
pp. 1972-1979
Author(s):  
Michael Bellone ◽  
Huy P. Pham ◽  
Beth H. Shaz ◽  
Patricia A. Shi
Keyword(s):  
Blood Cell ◽  
Retrospective Analysis ◽  
Red Blood Cell ◽  
Community Hospital ◽  
Cell Recovery

Equine bone marrow volume reduction, red blood cell depletion, and mononuclear cell recovery using the PrepaCyte-CB processing system

2015 ◽  
Vol 44 (2) ◽  
pp. 188-193 ◽  
Author(s):  
Andrew G. Burton ◽  
Kaitlin C. Clark ◽  
Dori L. Borjesson ◽  
Danielle D. Carrade ◽  
Julie Burges ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Blood Cell ◽  
Mononuclear Cell ◽  
Red Blood Cell ◽  
Processing System ◽  
Volume Reduction ◽  
Cell Depletion ◽  
Cell Recovery ◽  
Equine Bone
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