Hepatitis B virus DNA viral load determination in hepatitis B surface antigen-negative Swiss blood donors

Transfusion ◽  
2014 ◽  
Vol 54 (11) ◽  
pp. 2961-2967 ◽  
Author(s):  
Martin Stolz ◽  
Caroline Tinguely ◽  
Stefano Fontana ◽  
Christoph Niederhauser
Keyword(s):  
Viral Load ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Hepatitis B Virus Dna ◽  
B Virus ◽  
Viral Load Determination

scholarly journals Hepatitis B virus DNA and e antigen in serum from blood donors in the United Kingdom positive for hepatitis B surface antigen.

BMJ ◽  
1985 ◽  
Vol 290 (6469) ◽  
pp. 663-664 ◽  
Author(s):  
T J Harrison ◽  
V Bal ◽  
E G Wheeler ◽  
T J Meacock ◽  
J F Harrison ◽  
...  
Keyword(s):  
United Kingdom ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Hepatitis B Virus Dna ◽  
The United Kingdom ◽  
B Virus

Lack of correlation between hepatitis B surface antigen and hepatitis B virus DNA levels in blood donors

Transfusion ◽  
2005 ◽  
Vol 45 (6) ◽  
pp. 1039-1040 ◽  
Author(s):  
Jean-Pierre Allain ◽  
Francis Sarkodie ◽  
Daniel Candotti ◽  
Ohene Opare-Sem
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Hepatitis B Virus Dna ◽  
B Virus

scholarly journals Assessment of hepatitis B surface antigen negative blood units for HBV DNA among replacement blood donors in a hospital based blood bank in Nigeria

2021 ◽  
Vol 21 (3) ◽  
pp. 1141-1147
Author(s):  
Foluke Atinuke Fasola ◽  
Adeola Fowotade ◽  
Adedayo Faneye
Keyword(s):  
Viral Load ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Hbv Dna ◽  
Blood Safety ◽  
Infected Blood ◽  
B Virus

Background: Hepatitis B virus infection is one of the greatest threats to blood safety all over the world. The laboratory algorithm based on only the detection of hepatitis B surface antigen (HBsAg) leaves a gap for infected HBsAg negative donors to donate blood during the “window period” (WP) and late stages of infection. Objective: To estimate the frequency of the presence of HBV deoxyribonucleic acid (DNA) in HBsAg negative blood units screened using two different assays for HBsAg in a high endemic region. Methods: Frozen serum aliquot of 100 replacement blood donors who donated blood units that were HBsAg negative were retrieved and tested for HBV DNA. Sample positive for HBV DNA was sequenced by Sanger’s method, genotyped and the viral load was determined. Results: One sample (1%) was positive for HBV DNA. The HBV viral load of the sample was 768,000 IU/ml. The partial S-gene of the Hepatitis B virus isolated was genotype E using the NCBI viral genotyping tool. Conclusions: There is still a risk of HBV infected blood unit escaping detection when donor testing is limited to HBsAg screening. The use of NAT which can substantially reduce HBV infected blood donors from the donor pool should be considered. Keywords: Hepatitis B surface Antigen; Hepatitis B Virus; DNA; blood donors; blood safety.

scholarly journals Significance of hepatitis B surface antigen, IgM/IgG core antibody and hepatitis B virus DNA in blood donors

2021 ◽  
Vol 157 (1) ◽  
Author(s):  
Rosa F. Chiriboga-Ponce ◽  
Gabriela Cueva-Tirira ◽  
Carolina Crespo-Proaño ◽  
Andrés González-Rodríguez ◽  
Pedro Pineda-Males ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Hepatitis B Virus Dna ◽  
B Virus

Sensitivity of hepatitis B virus DNA transcription-mediated amplification testing in hepatitis B surface antigen?positive blood donations

Transfusion ◽  
2006 ◽  
Vol 46 (12) ◽  
pp. 2047-2052 ◽  
Author(s):  
Françoise Bouchardeau ◽  
Annie Girault ◽  
Annie Razer ◽  
Annabelle Servant-Delmas ◽  
Mélanie Mercier ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Hepatitis B Surface Antigen ◽  
Blood Donations ◽  
Dna Transcription ◽  
Hepatitis B Virus Dna ◽  
B Virus
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