Transfusion-associated hyperkalemic cardiac arrest in pediatric patients receiving massive transfusion

Transfusion ◽  
2013 ◽  
Vol 54 (1) ◽  
pp. 244-254 ◽  
Author(s):  
Angela C. Lee ◽  
Leila L. Reduque ◽  
Naomi L.C. Luban ◽  
Paul M. Ness ◽  
Blair Anton ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Pediatric Patients ◽  
Massive Transfusion

Massive Transfusion Protocols for Pediatric Patients

2016 ◽  
Vol 6 (2) ◽  
pp. 60 ◽  
Author(s):  
Hwan Tae Lee ◽  
Pil-Whan Park ◽  
Yiel-Hea Seo ◽  
Jeong-Yeal Ahn ◽  
Ja Young Seo ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Massive Transfusion

Abstract 168: Association Between Prehospital Advanced Airway Management for Pediatric Out-of-Hospital Cardiac Arrest and Survival

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
Masashi Okubo ◽  
Sho Komukai ◽  
Junichi Izawa ◽  
Koichiro Gibo ◽  
Kosuke Kiyohara ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Propensity Score ◽  
Airway Management ◽  
Patient Outcomes ◽  
Odds Ratio ◽  
Pediatric Patients ◽  
Time Dependent ◽  
Advanced Airway ◽  
Hospital Cardiac Arrest ◽  
Favorable Functional Outcome

Introduction: It is unclear whether prehospital advanced airway management (AAM: endotracheal intubation and supraglottic airway device placement) for pediatric patients with out-of-hospital cardiac arrest (OHCA) improves patient outcomes. Objective: To test the hypothesis that prehospital advanced airway management during pediatric OHCA is associated with patient outcomes. Methods: We conducted a secondary analysis of a nationwide, prospective, population-based OHCA registry in Japan. We included pediatric patients (<18 years) with OHCA in whom emergency medical services (EMS) personnel resuscitated and transported to medical institutions during 2014 and 2015. The primary outcome was one-month survival. Secondary outcome was one-month survival with favorable functional outcome, defined as cerebral performance category score 1 or 2. Patients who received AAM during cardiopulmonary resuscitation by EMS personnel at any given minute were sequentially matched with patients at risk of receiving AAM within the same minutes based on time-dependent propensity score calculated from a competing risk regression model in which we treated prehospital return of spontaneous circulation as a competing risk event. Results: We included 2,548 patients; 1,017 (39.9%) were infants (<1 year), 839 (32.9%) were children (1 year to 12 years), and 692 (27.2%) were adolescents. Of the 2,548, included patients, 336 (13.2%) underwent prehospital AAM during cardiac arrest. In the time-dependent propensity score matched cohort (n = 642), there were no significant differences in one-month survival (AAM: 32/321 [10.0%] vs. no AAM: 27/321 [8.4%]; odds ratio, 1.33 [95% CI, 0.80 to 2.21]) and one-month survival with favorable functional outcome (AAM: 6/321 [1.9%] vs. no AAM: 5/321 [1.6%]; odds ratio, 1.48 [95% CI, 0.41 to 5.40]). Conclusions: Among pediatric patients with OHCA, we found no associations between prehospital AAM and favorable patient outcomes.

scholarly journals Massive Transfusion Protocols for Pediatric Patients: Current Perspectives

2020 ◽  
Vol Volume 11 ◽  
pp. 163-172
Author(s):  
Meagan E Evangelista ◽  
Michaela Gaffley ◽  
Lucas P Neff
Keyword(s):  
Pediatric Patients ◽  
Massive Transfusion

scholarly journals ECMO for Cardiac Rescue after Accidental Intravenous Mepivacaine Application

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Michael Froehle ◽  
Nikolaus A. Haas ◽  
Guenther Kirchner ◽  
Deniz Kececioglu ◽  
Eugen Sandica
Keyword(s):  
Cardiac Arrest ◽  
Local Anaesthetic ◽  
Regional Anaesthesia ◽  
Pediatric Patients ◽  
Rare Complication ◽  
Treatment Options ◽  
Management Strategies ◽  
Lipid Emulsions ◽  
Neurological Damage ◽  
Broad Complex

Mepivacaine is a potent local anaesthetic and used for infiltration and regional anaesthesia in adults and pediatric patients. Intoxications with mepivacaine affect mainly the CNS and the cardiovascular system. We present a case of accidental intravenous mepivacaine application and intoxication of an infant resulting in seizure, broad complex bradyarrhythmia, arterial hypotension and finally cardiac arrest. The patient could be rescued by prolonged resuscitations and a rapid initiation of ECMO and survived without neurological damage. The management strategies of this rare complication including promising other treatment options with lipid emulsions are discussed.

scholarly journals Survival of pediatric patients after cardiopulmonary resuscitation for in-hospital cardiac arrest: a systematic review and meta-analysis

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Melaku Bimerew ◽  
Adam Wondmieneh ◽  
Getnet Gedefaw ◽  
Teshome Gebremeskel ◽  
Asmamaw Demis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cardiac Arrest ◽  
Cardiopulmonary Resuscitation ◽  
Hospital Discharge ◽  
Pediatric Patients ◽  
Meta Analysis ◽  
Cochrane Review ◽  
Probability Of Survival ◽  
Pooled Prevalence ◽  
Hospital Cardiac Arrest

Abstract Background In-hospital cardiac arrest is a major public health issue. It is a serious condition; most probably end up with death within a few minutes even with corrective measures. However, cardiopulmonary resuscitation is expected to increase the probability of survival and prevent neurological disabilities in patients with cardiac arrest. Having a pooled prevalence of survival to hospital discharge after cardiopulmonary resuscitation is vital to develop strategies targeted to increase probability of survival among patients with cardiac arrest. Therefore, this systematic review and meta-analysis was aimed to assess the pooled prevalence of survival to hospital discharge among pediatric patients who underwent cardiopulmonary resuscitation for in-hospital cardiac arrest. Methods PubMed, Google Scholar, and Cochrane review databases were searched. To have current (five-year) evidence, only studies published in 2016 to 2020 were included. The weighted inverse variance random-effects model at 95%CI was used to estimate the pooled prevalence of survival. Heterogeneity assessment, test of publication bias, and subgroup analyses were also employed accordingly. Results Twenty-five articles with a total sample size of 28,479 children were included in the final analysis. The pooled prevalence of survival to hospital discharge was found to be 46% (95% CI = 43.0–50.0%; I2 = 96.7%; p < 0.001). Based on subgroup analysis by “continent” and “income level”, lowest prevalence of pooled survival was observed in Asia (six studies; pooled survival =36.0% with 95% CI = 19.01–52.15%; I2 = 97.4%; p < 0.001) and in low and middle income countries (six studies, pooled survival = 34.0% with 95% CI = 17.0–51.0%, I2 = 97.67%, p < 0.001) respectively. Conclusion Although there was an extremely high heterogeneity among reported results (I2 = 96.7%), in this meta-analysis more than half of pediatric patients (54%) who underwent cardiopulmonary resuscitation for in-hospital cardiac arrest did not survived to hospital discharge. Therefore, developing further strategies and encouraging researches might be crucial.

scholarly journals Neuron-Specific Enolase, Serum-100B, Electroencephalogram as Indicators of Extent of Brain Damage in Post Cardiac Arrest Patients

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M Y Elseify ◽  
A R Ahmed ◽  
M O Shattah ◽  
S A Salaheldin
Keyword(s):  
Cardiac Arrest ◽  
Prospective Observational Study ◽  
Pediatric Patients ◽  
Neuron Specific Enolase ◽  
Pediatric Intensive Care ◽  
P Value ◽  
Study Group ◽  
Significant Relation ◽  
Mortality And Morbidity ◽  
Risk Of Mortality

Abstract Background Post cardiac arrest patients have high risk of mortality and morbidity. Brain injury plays an important role in determining patients’ outcome. Aim of the Work: To correlate the levels of Neuron-specific enolase (NSE), Serum-100B (S100B) and Electroencephalogarm patterns in post cardiac arrest pediatric patients with cardiac arrest circumstances and patients’ outcome. Patients and Methods: This prospective observational study was conducted in Pediatric Intensive Care Unit, Ain Shams University. It included 41 post cardiac arrest patients who underwent serum sampling for NSE, Serum 100B and Electroencephalogram. Results: In our study, 19.5% of patients survived to hospital discharge. Convulsions and sepsis were present in 21.9% and 82.9% of the study group respectively. Convulsions and sepsis were associated with higher mortality with relative risk 1.33 and 1.99 respectively. Serum NSE and serum 100B showed no statistically significant relation with outcome. NSE levels were positively correlated with duration of arrest. EEG patterns showed statistically significant differences when related to outcome with p value of 0.01. Conclusion: Post cardiac arrest patients need intense care especially regarding sepsis and convulsions. NSE levels are related to duration of arrest but not survival. S100B levels aren’t related to survival or duration of arrest. Different EEG Patterns are related to patients’ outcome.

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