scholarly journals Profiling thimet oligopeptidase‐mediated proteolysis in Arabidopsis thaliana

2021 ◽  
Author(s):  
Anthony A. Iannetta ◽  
Holden T. Rogers ◽  
Thualfeqar Al‐Mohanna ◽  
Juliana N. O’Brien ◽  
Andrew J. Wommack ◽  
...  
2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Holden Rogers ◽  
Leslie Hicks ◽  
Anthony Iannetta ◽  
Sorina Popescu

Author(s):  
Ruiying Wang ◽  
Krithika Rajagopalan ◽  
Kianoush Sadre-Bazzaz ◽  
Magali Moreau ◽  
Daniel F. Klessig ◽  
...  

Thimet oligopeptidase (TOP) is a zinc-dependent metallopeptidase. Recent studies suggest thatArabidopsis thalianaTOP1 and TOP2 are targets for salicylic acid (SA) binding and participate in SA-mediated plant innate immunity. The crystal structure ofA. thalianaTOP2 has been determined at 3.0 Å resolution. Comparisons to the structure of human TOP revealed good overall structural conservation, especially in the active-site region, despite their weak sequence conservation. The protein sample was incubated with the photo-activated SA analog 4-azido-SA and exposed to UV irradiation before crystallization. However, there was no conclusive evidence for the binding of SA based on the X-ray diffraction data. Further studies are needed to elucidate the molecular mechanism of how SA regulates the activity ofA. thalianaTOP1 and TOP2.


1994 ◽  
Vol 5 (4) ◽  
pp. 551-558 ◽  
Author(s):  
Seok So Chang ◽  
Soon Ki Park ◽  
Byung Chul Kim ◽  
Bong Joong Kang ◽  
Dal Ung Kim ◽  
...  

1995 ◽  
Vol 95 (2) ◽  
pp. 260-266 ◽  
Author(s):  
Maarten Koornneef ◽  
Corrie Hanhart ◽  
Patty van Loenen-Martinet ◽  
Hetty Blankestijn de Vries

1992 ◽  
Vol 84 (4) ◽  
pp. 561-567 ◽  
Author(s):  
Poul E. Jensen ◽  
Michael Kristensen ◽  
Tine Hoff ◽  
Jan Lehmbeck ◽  
Bjarne M. Stummann ◽  
...  

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
F Nabbie ◽  
O Shperdheja ◽  
J Millot ◽  
J Lindberg ◽  
B Peethambaran

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