scholarly journals Cytochrome P450 CYP81A10v7 in Lolium rigidum confers metabolic resistance to herbicides across at least five modes of action

2020 ◽  
Author(s):  
Heping Han ◽  
Qin Yu ◽  
Roland Beffa ◽  
Susana González ◽  
Frank Maiwald ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Lolium Rigidum ◽  
Metabolic Resistance ◽  
Modes Of Action ◽  
Resistance To Herbicides

scholarly journals Cross-Resistance to Herbicides in Annual Ryegrass (Lolium rigidum)

1990 ◽  
Vol 94 (3) ◽  
pp. 1180-1186 ◽  
Author(s):  
John M. Matthews ◽  
Joseph A. M. Holtum ◽  
David R. Liljegren ◽  
Barbara Furness ◽  
Stephen B. Powles
Keyword(s):  
Cross Resistance ◽  
Annual Ryegrass ◽  
Lolium Rigidum ◽  
Resistance To Herbicides

scholarly journals Evaluating insecticide resistance across African districts to aid malaria control decisions

2020 ◽  
Vol 117 (36) ◽  
pp. 22042-22050 ◽  
Author(s):  
Catherine L. Moyes ◽  
Duncan K. Athinya ◽  
Tara Seethaler ◽  
Katherine E. Battle ◽  
Marianne Sinka ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Pyrethroid Resistance ◽  
Resistance Mechanisms ◽  
World Health ◽  
Malaria Vector Control ◽  
Ensemble Model ◽  
Metabolic Resistance ◽  
The World ◽  
Susceptibility Tests ◽  
Health Organization

Malaria vector control may be compromised by resistance to insecticides in vector populations. Actions to mitigate against resistance rely on surveillance using standard susceptibility tests, but there are large gaps in the monitoring data across Africa. Using a published geostatistical ensemble model, we have generated maps that bridge these gaps and consider the likelihood that resistance exceeds recommended thresholds. Our results show that this model provides more accurate next-year predictions than two simpler approaches. We have used the model to generate district-level maps for the probability that pyrethroid resistance inAnopheles gambiaes.l. exceeds the World Health Organization thresholds for susceptibility and confirmed resistance. In addition, we have mapped the three criteria for the deployment of piperonyl butoxide-treated nets that mitigate against the effects of metabolic resistance to pyrethroids. This includes a critical review of the evidence for presence of cytochrome P450-mediated metabolic resistance mechanisms across Africa. The maps for pyrethroid resistance are available on the IR Mapper website, where they can be viewed alongside the latest survey data.

scholarly journals Correction: Cytochrome P450 metabolic resistance (CYP6P9a) to pyrethroids imposes a fitness cost in the major African malaria vector Anopheles funestus

Heredity ◽  
2020 ◽  
Vol 125 (5) ◽  
pp. 371-371 ◽  
Author(s):  
Magellan Tchouakui ◽  
Jacob Riveron Miranda ◽  
Leon M. J. Mugenzi ◽  
Doumani Djonabaye ◽  
Murielle J. Wondji ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Malaria Vector ◽  
Anopheles Funestus ◽  
Fitness Cost ◽  
Metabolic Resistance

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

scholarly journals Monitoring Insecticide Susceptibility in Aedes Aegypti Populations from the Two Biggest Cities, Ouagadougou and Bobo-Dioulasso, in Burkina Faso: Implication of Metabolic Resistance

2020 ◽  
Vol 5 (2) ◽  
pp. 84
Author(s):  
Moussa Namountougou ◽  
Dieudonné Diloma Soma ◽  
Mahamoudou Balboné ◽  
Didier Alexandre Kaboré ◽  
Mahamadi Kientega ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Aedes Aegypti ◽  
West Africa ◽  
Insecticide Resistance ◽  
Burkina Faso ◽  
Urban Areas ◽  
Mortality Rates ◽  
Metabolic Resistance ◽  
Bobo Dioulasso ◽  
Glutathione S Transferases

In West Africa, Aedes aegypti remains the major vector of dengue virus. Since 2013, dengue fever has been reemerging in Burkina Faso with annual outbreaks, thus becoming a major public health problem. Its control relies on vector control, which is unfortunately facing the problem of insecticide resistance. At the time of this study, although data on phenotypic resistance were available, information related to the metabolic resistance in Aedes populations from Burkina Faso remained very scarce. Here, we assessed the phenotypic and the metabolic resistance of Ae. aegypti populations sampled from the two main urban areas (Ouagadougou and Bobo-Dioulasso) of Burkina Faso. Insecticide susceptibility bioassays to chlorpyriphos-methyl 0.4%, bendiocarb 0.1% and deltamethrin 0.05% were performed on natural populations of Ae. aegypti using the WHO protocol. The activity of enzymes involved in the rapid detoxification of insecticides, especially non-specific esterases, oxidases (cytochrome P450) and glutathione-S-transferases, was measured on individual mosquitos. The mortality rates for deltamethrin 0.05% were low and ranged from 20.72% to 89.62% in the Bobo-Dioulasso and Ouagadougou sites, respectively. When bendiocarb 0.1% was tested, the mortality rates ranged from 7.73% to 71.23%. Interestingly, in the two urban areas, mosquitoes were found to be fully susceptible to chlorpyriphos-methyl 0.4%. Elevated activity of non-specific esterases and glutathione-S-transferases was reported, suggesting multiple resistance mechanisms involved in Ae. aegypti populations from Bobo-Dioulasso and Ouagadougou (including cytochrome P450). This update to the insecticide resistance status within Ae. aegypti populations in the two biggest cities is important to better plan dengue vectors control in the country and provides valuable information for improving vector control strategies in Burkina Faso, West Africa.

Sign in / Sign up

Export Citation Format

Share Document