scholarly journals New insights into structural organization and gene duplication in a 1.75-Mb genomic region harboring the α-gliadin gene family inAegilops tauschii, the source of wheat D genome

2017 ◽  
Vol 92 (4) ◽  
pp. 571-583 ◽  
Author(s):  
Naxin Huo ◽  
Lingli Dong ◽  
Shengli Zhang ◽  
Yi Wang ◽  
Tingting Zhu ◽  
...  
Keyword(s):  
Gene Duplication ◽  
Gene Family ◽  
Structural Organization ◽  
Genomic Region ◽  
D Genome

scholarly journals Identification of members of the P-glycoprotein multigene family.

1989 ◽  
Vol 9 (3) ◽  
pp. 1224-1232 ◽  
Author(s):  
W F Ng ◽  
F Sarangi ◽  
R L Zastawny ◽  
L Veinot-Drebot ◽  
V Ling
Keyword(s):  
Multidrug Resistance ◽  
Gene Duplication ◽  
Gene Family ◽  
Multigene Family ◽  
Rhesus Monkeys ◽  
Genomic Library ◽  
Duplication Event ◽  
Glycoprotein Gene ◽  
P Glycoprotein ◽  
Exon Probe

Overproduction of P-glycoprotein is intimately associated with multidrug resistance. This protein appears to be encoded by a multigene family. Thus, differential expression of different members of this family may contribute to the complexity of the multidrug resistance phenotype. Three lambda genomic clones isolated from a hamster genomic library represent different members of the hamster P-glycoprotein gene family. Using a highly conserved exon probe, we found that the hamster P-glycoprotein gene family consists of three genes. We also found that the P-glycoprotein gene family consists of three genes in mice but has only two genes in humans and rhesus monkeys. The hamster P-glycoprotein genes have similar exon-intron organizations within the 3' region encoding the cytoplasmic domains. We propose that the hamster P-glycoprotein gene family arose from gene duplication. The hamster pgp1 and pgp2 genes appear to be more closely related to each other than either gene is to the pgp3 gene. We speculate that the hamster pgp1 and pgp2 genes arose from a recent gene duplication event and that primates did not undergo this duplication and therefore contain only two P-glycoprotein genes.

scholarly journals Multi-tissue transcriptome analysis of two Begonia species reveals dynamic patterns of evolution in the chalcone synthase gene family

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Katie Emelianova ◽  
Andrea Martínez Martínez ◽  
Lucia Campos-Dominguez ◽  
Catherine Kidner
Keyword(s):  
Gene Duplication ◽  
Gene Family ◽  
Genome Size ◽  
Stress Responses ◽  
Chalcone Synthase ◽  
Expression Profiles ◽  
Rna Seq ◽  
Biotic And Abiotic Stress ◽  
Chalcone Synthase Gene ◽  
Study Species

AbstractBegonia is an important horticultural plant group, as well as one of the most speciose Angiosperm genera, with over 2000 described species. Genus wide studies of genome size have shown that Begonia has a highly variable genome size, and analysis of paralog pairs has previously suggested that Begonia underwent a whole genome duplication. We address the contribution of gene duplication to the generation of diversity in Begonia using a multi-tissue RNA-seq approach. We chose to focus on chalcone synthase (CHS), a gene family having been shown to be involved in biotic and abiotic stress responses in other plant species, in particular its importance in maximising the use of variable light levels in tropical plants. We used RNA-seq to sample six tissues across two closely related but ecologically and morphologically divergent species, Begonia conchifolia and B. plebeja, yielding 17,012 and 19,969 annotated unigenes respectively. We identified the chalcone synthase gene family members in our Begonia study species, as well as in Hillebrandia sandwicensis, the monotypic sister genus to Begonia, Cucumis sativus, Arabidopsis thaliana, and Zea mays. Phylogenetic analysis suggested the CHS gene family has high duplicate turnover, all members of CHS identified in Begonia arising recently, after the divergence of Begonia and Cucumis. Expression profiles were similar within orthologous pairs, but we saw high inter-ortholog expression variation. Sequence analysis showed relaxed selective constraints on some ortholog pairs, with substitutions at conserved sites. Evidence of pseudogenisation and species specific duplication indicate that lineage specific differences are already beginning to accumulate since the divergence of our study species. We conclude that there is evidence for a role of gene duplication in generating diversity through sequence and expression divergence in Begonia.

Two gene duplication events in the human and primate dopamine D5 receptor gene family

Gene ◽  
1995 ◽  
Vol 154 (2) ◽  
pp. 153-158 ◽  
Author(s):  
Adriano Marchese ◽  
Timothy V. Beischlag ◽  
Tuan Nguyen ◽  
Hyman B. Niznik ◽  
Richard L. Weinshank ◽  
...  
Keyword(s):  
Gene Duplication ◽  
Gene Family ◽  
Receptor Gene ◽  
Duplication Events ◽  
Dopamine D5 Receptor ◽  
Receptor Gene Family
Sign in / Sign up

Export Citation Format

Share Document