scholarly journals Assessing the impact of a school-based latrine cleaning and handwashing program on pupil absence in Nyanza Province, Kenya: a cluster-randomized trial

2014 ◽  
Vol 19 (10) ◽  
pp. 1185-1197 ◽  
Author(s):  
Bethany A. Caruso ◽  
Matthew C. Freeman ◽  
Joshua V. Garn ◽  
Robert Dreibelbis ◽  
Shadi Saboori ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Cluster Randomized Trial ◽  
Nyanza Province ◽  
School Based ◽  
Cluster Randomized ◽  
The Impact

scholarly journals Intermittent preventive treatment of malaria delivered to primary schoolchildren provided effective individual protection in Jinja, Uganda: secondary outcomes of a cluster-randomized trial (START-IPT)

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Andrea M. Rehman ◽  
Catherine Maiteki-Sebuguzi ◽  
Samuel Gonahasa ◽  
Jaffer Okiring ◽  
Simon P. Kigozi ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Intermittent Preventive Treatment ◽  
Preventive Treatment ◽  
Cluster Randomized Trial ◽  
Adjusted Risk ◽  
School Based ◽  
Primary Schoolchildren ◽  
Secondary Outcomes ◽  
Cluster Randomized ◽  
The Impact

Abstract Background Intermittent preventive treatment (IPT) of malaria is recommended as policy for certain high-risk populations, but not currently for schoolchildren. A cluster-randomized trial was conducted to evaluate the effect of IPT with dihydroartemisinin–piperaquine (DP) on primary schoolchildren in Jinja, Uganda. Results of the impact of IPT of schoolchildren on community-level transmission have been reported previously. Here, secondary outcomes from a school-based survey are presented. Methods Eighty-four clusters (one primary school plus 100 households) were randomized to intervention and control (1:1 ratio). Participants from intervention schools received monthly IPT with DP for up to 6 rounds (June–December 2014). At endline (November–December 2014), randomly selected children from all 84 schools were surveyed (13 per school) and thick blood smears were done. Those with fever or history of fever were tested with rapid diagnostic tests (RDTs) for malaria. Haemoglobin was measured in every fifth participant. Outcome measures included prevalence of asexual parasites and gametocytes (by microscopy), and prevalence of anaemia. Prevalence outcomes were analysed using generalized linear Poisson models with log link function, incorporating a cluster-level random intercept and quantified using prevalence risk ratios. Results Among 23,280 students listed on the 42 intervention school registers, 10,079 (43.3%) aged 5–20 years were enrolled into the IPT intervention and received at least one dose of DP; of these, 9286 (92.1%) received at least one full (3-day) course. In total, 1092 children were enrolled into the final school survey (546 per arm) and had a thick blood smear done; of these, 255 had haemoglobin measured (129 intervention, 126 control). Children in the intervention arm were less likely to have asexual parasites (9.2% intervention vs 44.1% control, adjusted risk ratio [aRR] 0.22 [95% CI 0.16–0.30] p < 0.001), gametocytes (3.1% intervention vs 9.5% control, aRR 0.34 [95% CI 0.20–0.56] p < 0.001), fever (20.2% intervention vs 56.2% control, aRR 0.35 [95% CI 0.25–0.50] p < 0.001), or symptomatic malaria (5.1% intervention vs 35.7% control, aRR 0.14 [95% CI 0.08–0.26] p < 0.001). Prevalence of anaemia and mean haemoglobin were similar in both study arms. Conclusions School-aged children are a major reservoir of malaria parasites. Delivering IPT to schoolchildren would benefit individual children and may reduce transmission. School-based IPT could help to intensify malaria control toward elimination, and should be considered for policies and programmes. Trial registration Clinicaltrials.gov (NCT02009215), Registered 11 December 2013. https://clinicaltrials.gov/ct2/show/NCT02009215

scholarly journals The impact of a school-based water supply and treatment, hygiene, and sanitation programme on pupil diarrhoea: a cluster-randomized trial

2013 ◽  
Vol 142 (2) ◽  
pp. 340-351 ◽  
Author(s):  
M. C. FREEMAN ◽  
T. CLASEN ◽  
R. DREIBELBIS ◽  
S. SABOORI ◽  
L. E. GREENE ◽  
...  
Keyword(s):  
Water Supply ◽  
Randomized Trial ◽  
Cluster Randomized Trial ◽  
Water Source ◽  
Diarrhoeal Disease ◽  
School Based ◽  
Water Supply And Treatment ◽  
Cluster Randomized ◽  
Water Scarce ◽  
The Impact

SUMMARYThe impact of improved water, sanitation, and hygiene (WASH) access on mitigating illness is well documented, although impact of school-based WASH on school-aged children has not been rigorously explored. We conducted a cluster-randomized trial in Nyanza Province, Kenya to assess the impact of a school-based WASH intervention on diarrhoeal disease in primary-school pupils. Two study populations were used: schools with a nearby dry season water source and those without. Pupils attending ‘water-available’ schools that received hygiene promotion and water treatment (HP&WT) and sanitation improvements showed no difference in period prevalence or duration of illness compared to pupils attending control schools. Those pupils in schools that received only the HP&WT showed similar results. Pupils in ‘water-scarce’ schools that received a water-supply improvement, HP&WT and sanitation showed a reduction in diarrhoea incidence and days of illness. Our study revealed mixed results on the impact of improvements to school WASH improvements on pupil diarrhoea.

scholarly journals The impact of providing rapid diagnostic malaria tests on fever management in the private retail sector in Ghana: a cluster randomized trial

BMJ ◽  
2015 ◽  
Vol 350 (mar04 8) ◽  
pp. h1019-h1019 ◽  
Author(s):  
E. K. Ansah ◽  
S. Narh-Bana ◽  
H. Affran-Bonful ◽  
C. Bart-Plange ◽  
B. Cundill ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Cluster Randomized Trial ◽  
Retail Sector ◽  
Cluster Randomized ◽  
The Impact ◽  
Fever Management

scholarly journals School-based mental health intervention for children in war-affected Burundi: a cluster randomized trial

BMC Medicine ◽  
2014 ◽  
Vol 12 (1) ◽  
Author(s):  
Wietse A Tol ◽  
Ivan H Komproe ◽  
Mark JD Jordans ◽  
Aline Ndayisaba ◽  
Prudence Ntamutumba ◽  
...  
Keyword(s):  
Mental Health ◽  
Randomized Trial ◽  
Cluster Randomized Trial ◽  
Health Intervention ◽  
Mental Health Intervention ◽  
School Based ◽  
Cluster Randomized

A theory-guided school-based intervention in order to improve adolescents' oral self-care: a cluster randomized trial

2015 ◽  
Vol 26 (2) ◽  
pp. 100-109 ◽  
Author(s):  
Jolanta Aleksejūnienė ◽  
Vilma Brukienė ◽  
Lina Džiaugyte ◽  
Vytautė Pečiulienė ◽  
Rūta Bendinskaitė
Keyword(s):  
Randomized Trial ◽  
Self Care ◽  
Cluster Randomized Trial ◽  
School Based Intervention ◽  
School Based ◽  
Cluster Randomized
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